Publication:
A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide

dc.contributor.authorÖzet, Ahmet
dc.contributor.authorAtaergin, S.
dc.contributor.authorArpacı, F.
dc.contributor.authorÖzturk, Bülent
dc.contributor.authorArpacı, Fikret
dc.contributor.authorÖztürk, M.
dc.contributor.authorKomürcü, S.
dc.contributor.authorKuzhan, O.
dc.contributor.buuauthorKanat, O.
dc.contributor.departmentTıp Fakültesi
dc.contributor.scopusid6602187347
dc.date.accessioned2022-01-17T08:06:01Z
dc.date.available2022-01-17T08:06:01Z
dc.date.issued2006-06
dc.description.abstractScalp angiosarcoma is a rare and highly malignant tumour originating from endothelial cells of vessels and occurring predominantly in elderly men. Its prognosis is poor and the 5-year survival rate of patients is reported to be 12–33% [1]. Complete surgical excision with wide margins remains the cornerstone of therapy for localised tumours. Additional radiotherapy may provide improved local control. Given the rarity of this tumour, an optimum chemotherapy regimen has not yet been defined for metastatic cases. Here we report a case of scalp angiosarcoma with local recurrence and distant metastases which was successfully treated with a combination chemotherapy consisting of adriamycin, cisplatin, ifosfamide and mesna (APIM). A 24-year-old man presented to a plastic surgeon in January 2005 with a painless nodule on the scalp measuring 3 cm in diameter. Surgical total excision of the nodule was carried out, providing a negative surgical margin (2 cm). The diagnosis of angiosarcoma was confirmed pathologically. An X-ray of the scull, magnetic resonance imaging of the brain and computed tomography of the neck, thorax and abdomen revealed no evidence of local or distant metastases at the time of diagnosis. The patient was not given any adjuvant therapy. Five months after the surgery, the patient developed two new angiosarcoma lesions (1.5 and 2 cm in diameter) on different sites of the scalp. In addition, computed tomography of the neck and chest revealed conglomerate lymph nodes on the left side of the neck and five small metastatic nodules, up to 1.5 cm greatest dimension in bilateral lung fields.
dc.identifier.citationKanat, O. vd. (2006). ''A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide''. Clinical Oncology, 18(5), 426-427.
dc.identifier.endpage427
dc.identifier.issn0936-6555
dc.identifier.issue5
dc.identifier.pubmed16817336
dc.identifier.scopus2-s2.0-33646118234
dc.identifier.startpage426
dc.identifier.urihttps://doi.org/10.1016/j.clon.2006.03.002
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0936655506000951
dc.identifier.urihttp://hdl.handle.net/11452/24116
dc.identifier.volume18
dc.identifier.wos000237988700012
dc.indexed.wosSCIE
dc.language.isoen
dc.publisherElsevier
dc.relation.collaborationSanayi
dc.relation.journalClinical Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectOncology
dc.subjectMesna
dc.subjectIfosfamide
dc.subjectDoxorubicin
dc.subjectCisplatin
dc.subjectSkin neoplasms
dc.subjectScalp
dc.subjectMale
dc.subjectIfosfamide
dc.subjectHumans
dc.subject.emtreeMesna
dc.subject.emtreeIfosfamide
dc.subject.emtreeDoxorubicin
dc.subject.emtreeCisplatin
dc.subject.emtreeSkin surgery
dc.subject.emtreeSkin nodule
dc.subject.emtreeScalp tumor
dc.subject.emtreePriority journal
dc.subject.emtreeNeutropenia
dc.subject.emtreeNausea
dc.subject.emtreeMale
dc.subject.emtreeLymph node metastasis
dc.subject.emtreeLung metastasis
dc.subject.emtreeLetter
dc.subject.emtreeHuman
dc.subject.emtreeHistopathology
dc.subject.emtreeFollow up
dc.subject.emtreeDrug tolerability
dc.subject.emtreeComputer assisted tomography
dc.subject.emtreeCase report
dc.subject.emtreeCancer recurrence
dc.subject.emtreeCancer combination chemotherapy
dc.subject.emtreeAngiosarcoma
dc.subject.emtreeAdvanced cancer
dc.subject.emtreeAdult
dc.subject.meshTreatment outcome
dc.subject.meshSkin neoplasms
dc.subject.meshScalp
dc.subject.meshMale
dc.subject.meshIfosfamide
dc.subject.meshHumans
dc.subject.meshHemangiosarcoma
dc.subject.meshHead and neck neoplasms
dc.subject.meshDoxorubicin
dc.subject.meshCisplatin
dc.subject.meshAntineoplastic combined chemotherapy protocols
dc.subject.meshAdult
dc.subject.scopusAngiosarcoma; Scalp; Vascular Tumor
dc.subject.wosOncology
dc.titleA case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide
dc.typeLetter
dc.wos.quartileQ4
dc.wos.quartileQ2
dspace.entity.typePublication
local.contributor.departmentTıp Fakültesi
local.indexed.atScopus
local.indexed.atWOS

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