1996 Cilt 15 Sayı 1-2-3

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Sivrisinek kovucu likid piretroid insektisid preparatının (bioalletrin) ratlarda kronik toksik etkileri
(Uludağ Üniversitesi, 1996) Özbilgin, Selda; Sonal, Songül; Mor, Firdevs; Uludağ Üniversitesi/Veteriner Fakültesi.
Chronic toxicological effects and histopathologic aspects of liquid mosquito repellent which contains bioallethrin, a pyrethroid insecticide, was administered to rats by inhalation for eight hours daily for four months were examined. Smoke-exposed rats clinically showed signs of chronic neurotoxicity. In the lavage fluid of lungs of smoke-exposed rats, the levels of total protein were significantly higher and the levels of acid phosphatase were significantly lower (p < 0.01) than those of controls. There were significant increases ofsenlm enzymes, including total protein, globulin (p < 0.001) and acid phosphatase (p < 0.05), but there were no significant increases of serum urea and urea nitrogen, albumin, aspartate aminotranferase and gamma glutamyltranspeptidase. The level of serum thyroxine were decreased significantly (p < 0.05), but no significant decrease was observed in triiodothyronin