Effect of misoprostol on acute cisplatin nephrotoxicity

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dc.contributor.authorAntypas, G.
dc.contributor.buuauthorKurt, Ender
dc.contributor.buuauthorManavoğlu, Osman
dc.contributor.buuauthorDilek, Kamil
dc.contributor.buuauthorOrhan, Bulent
dc.contributor.buuauthorEvrensel, Türkkan
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-9732-5340tr_TR
dc.contributor.researcheridAAJ-1027-2021tr_TR
dc.date.accessioned2021-12-24T06:31:04Z
dc.date.available2021-12-24T06:31:04Z
dc.date.issued1999
dc.descriptionBu çalışma, 10-14 Eylül 1998 tarihleri arasında İzmir[Türkiye]'de düzenlenen 2nd Congress of the Balkan-Union-of-Oncology'de bildiri olarak sunulmuştur.tr_TR
dc.description.abstractProtective effects of misoprostol on non steroidal antiinflammatory drugs (NSAIDs) and cyclosporine nephrotoxicity is well described in the literature, but the role of misoprostol in cisplatin nephrotoxicity is not fully understood. In our study, we planned to investigate the protective effect of misoprostol in acute cisplatin nephrotoxicity. Our patient group consisted 28 patient with lung cancer. All patients received cisplatin + etoposide chemotherapy regimen. The patients were divided into two groups. Misoprostol Group (14 patients); was given misoprostol 100 mu g qid (po) during chemotherapy. Control Group (14 patients); only received chemotherapy. Glomerular and proximal tubular functions were measured in both groups before the onset of chemotherapy and on the 2(nd) and 6(th) days of chemotherapy. As a result of our study, we have not been able to show the protective effect of misoprostol in tubular and glomerular functional disturbances due to cisplatin administration.en_US
dc.description.sponsorshipBalkan Union Oncolen_US
dc.identifier.citationKurt, E. vd. (1999). "Effect of misoprostol on acute cisplatin nephrotoxicity". ed. G Antypas. 2nd Balkan Congress of Oncology, 401-406.en_US
dc.identifier.endpage406tr_TR
dc.identifier.isbn88-323-0910-6
dc.identifier.startpage401tr_TR
dc.identifier.urihttp://hdl.handle.net/11452/23535
dc.identifier.wos000081930300062tr_TR
dc.indexed.wosCPCIStr_TR
dc.language.isoenen_US
dc.publisherMedimond S R Len_US
dc.relation.journal2nd Balkan Congress of Oncologytr_TR
dc.relation.publicationcategoryKonferans Öğesi - Uluslararasıtr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOncologyen_US
dc.subjectProstaglandin-e1 analog misoprostolen_US
dc.subjectRenal-functionen_US
dc.subjectCyclosporine nephrotoxicityen_US
dc.subjectOral misoprostolen_US
dc.subjectIndomethacin Cellsen_US
dc.subjectProtectionen_US
dc.subjectCirrhosisen_US
dc.subjectKidneysen_US
dc.subjectInjuryen_US
dc.subjectCellsen_US
dc.subject.wosOncologyen_US
dc.titleEffect of misoprostol on acute cisplatin nephrotoxicityen_US
dc.typeProceedings Paper

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