Pediatrik Behçet hastalarının klinik ve demografik özellikleri
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Date
2008
Authors
Toker, Semra Çıkman
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Publisher
Uludağ Üniversitesi
Abstract
Amaç: Bu çalışmada; pediatrik Behçet hastalarının erişkin yaş grubu ile klinikdemografik özelliklerinin karşılaştırılması amaçlandı. Gereç ve Yöntem: 1992-2007 yılları arasında Uludağ Üniversitesi Tıp Fakültesi Dermatoloji AD Behçet Polikliniğinde takip edilen 18 yaş ve altı çocukların klinikdemografik özellikleri retrospektif olarak incelendi. Olguların yaş, cinsiyet, oral aft, genital ülser, eritema nodosum, papülopüstül varlığı; paterji testi pozitişiği; göz, eklem, nörolojik, gastrointestinal sistem ve renal tutulumları ve HLA-B5 pozitişiği ile ilgili bilgiler dosyalarından kayıt edildi. Bulgular: Uluslararası Behçet Çalışma Grubu tanı kriterlerine göre tanı konulduğu tarih itibariyle 0-18 yaş arasında olduğu belirlenen 30 olgu bulunmakta idi. Hastaların yaş ortalaması 15,9 idi. Tanı konulduğu anda olguların büyük kısmı 17-18 yaşlarındaydı (%43,3). On yaşın altında sadece 1 olgu vardı. Oral aft olguların tamamında, genital ülser ya da skarı 15’i kız 8’i erkek toplam 23 hastada saptandı (%76,6). Göz tutulumu 8’i kız 10’u erkek 18 hastada (%60); eritema nodosum 8’i kız 5’i erkek 13 hastada (%43,3), papülopüstül 10’u kız 6’sı erkek 16 hastada (%53,3), paterji pozitişiği 7’si kız 5’i erkek 12 hastada (%36,6) vardı. Vasküler semptomlar 2 hastada, artralji-artrit 15 hastada, nörolojik tutulum 4 hastada saptandı. Sonuç: Bu çalışmada, 0-18 yaş grubu Behçet hastalarının göz tutulumunun erişkin yaş grubundan daha sık olduğu, ancak diğer mukokutanöz bulguların benzer oranlarda görüldüğü sonucuna varıldı.
Aim: In this study, we aimed to compare the clinical and demographic features of pediatric Behçet’s patients with those of adult age. Materials and Method: We examined the clinical and demographic features of the 18 and under 18-year-old children who were followed-up in the Behçet's Center of Uluda¤ University Medical Faculty between 1992 and 2007, retrospectively. The information of age, sex, presence of oral aphthous ulcers, genital ulcers, erythema nodosum, papulopustular eruption, pathergy test positivity, ocular, articular, neurological, gastrointestinal, renal involvements and HLA-B5 positivity were obtained from the medical charts of the patients. Results: There were 30 pediatric Behçet diagnosed according to the diagnostic criteria of International Study Group for Behçet's Disease. The mean age of the patients was 15.9. At the time of the diagnosis, most of the patients were aged between 17-18 (43.3%). There was only one patient under 10. Oral aphthae was observed in all, and genital ulceration or the scar of the ulcer was observed in 23 patients; 15 females, 8 males (76.6%). Ocular involvement was present in 18 patients; 8 females, 10 males (60%); erythema nodosum in 13 patients; 8 females, 5 males (43.3%), papulopustular eruption in 16 patients; 10 females, 6 males and pathergy test positivity in 12 patients; 7 females, 5 males (36.6%). Vascular symptoms were observed in 2 patients, arthralgia-arthritis in 15 patients and neurological involvement in 4 patients. Conclusion: In this study, it was concluded that ocular involvement was more frequent in Behçet’s patients aged between 0-18 than adult Behçet’s patients, but mucocutaneous findings had similar frequency.
Aim: In this study, we aimed to compare the clinical and demographic features of pediatric Behçet’s patients with those of adult age. Materials and Method: We examined the clinical and demographic features of the 18 and under 18-year-old children who were followed-up in the Behçet's Center of Uluda¤ University Medical Faculty between 1992 and 2007, retrospectively. The information of age, sex, presence of oral aphthous ulcers, genital ulcers, erythema nodosum, papulopustular eruption, pathergy test positivity, ocular, articular, neurological, gastrointestinal, renal involvements and HLA-B5 positivity were obtained from the medical charts of the patients. Results: There were 30 pediatric Behçet diagnosed according to the diagnostic criteria of International Study Group for Behçet's Disease. The mean age of the patients was 15.9. At the time of the diagnosis, most of the patients were aged between 17-18 (43.3%). There was only one patient under 10. Oral aphthae was observed in all, and genital ulceration or the scar of the ulcer was observed in 23 patients; 15 females, 8 males (76.6%). Ocular involvement was present in 18 patients; 8 females, 10 males (60%); erythema nodosum in 13 patients; 8 females, 5 males (43.3%), papulopustular eruption in 16 patients; 10 females, 6 males and pathergy test positivity in 12 patients; 7 females, 5 males (36.6%). Vascular symptoms were observed in 2 patients, arthralgia-arthritis in 15 patients and neurological involvement in 4 patients. Conclusion: In this study, it was concluded that ocular involvement was more frequent in Behçet’s patients aged between 0-18 than adult Behçet’s patients, but mucocutaneous findings had similar frequency.
Description
Keywords
Behçet hastalığı, Pediatrik yaş grubu, Behçet’s disease, Pediatric age group
Citation
Sarıcaoğlu, H. vd. (2008). "Pediatrik Behçet hastalarının klinik ve demografik özellikleri". Güncel Pediatri, 6(3), 89-93.