Is parenteral levothyroxine therapy safe in intractable hypothyroidism?
dc.contributor.author | Peynirci, Hande | |
dc.contributor.author | Taşkıran, Bengür | |
dc.contributor.buuauthor | Ertürk, Erdinç | |
dc.contributor.buuauthor | Şişman, Pınar | |
dc.contributor.buuauthor | Ersoy, Canan | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolik Bozukluklar Anabilim Dalı. | tr_TR |
dc.contributor.researcherid | AAJ-6536-2021 | tr_TR |
dc.contributor.researcherid | AAH-8861-2021 | tr_TR |
dc.contributor.scopusid | 7005488796 | tr_TR |
dc.contributor.scopusid | 57190169474 | tr_TR |
dc.contributor.scopusid | 6701485882 | tr_TR |
dc.date.accessioned | 2023-10-04T08:12:54Z | |
dc.date.available | 2023-10-04T08:12:54Z | |
dc.date.issued | 2018-06 | |
dc.description.abstract | Case: A 32-year old woman was admitted to the hospital due to intractable hypothyroidism refractory to high dose of oral L-thyroxine therapy. She underwent total thyroidectomy and radioactive iodine therapy due to papillary thyroid cancer. After excluding poor adherence to therapy and malabsorption, levothyroxine absorption test was performed. No response was detected. Transient neurologic symptoms developed during the test. She developed 3 attacks consisting of neurologic symptoms during high dose administration. The patient was considered a case of isolated L-thyroxine malabsorption. She became euthyroid after intramuscular twice weekly L-thyroxine therapy. Discussion: There are a few case reports regarding isolated L-thyroxine. We report successful long term results of twice weekly administered intramuscular L-thyroxine therapy. We also draw attention to neurologic side effects of high dose L-thyroxine therapy. | en_US |
dc.identifier.citation | Peynirci, H. vd. (2018). ''Is parenteral levothyroxine therapy safe in intractable hypothyroidism?''. Journal of the National Medical Association, 110(3), 245-249. | en_US |
dc.identifier.endpage | 249 | tr_TR |
dc.identifier.issn | 0027-9684 | |
dc.identifier.issn | 1943-4693 | |
dc.identifier.issue | 3 | tr_TR |
dc.identifier.pubmed | 29778126 | tr_TR |
dc.identifier.scopus | 2-s2.0-85020916109 | tr_TR |
dc.identifier.startpage | 245 | tr_TR |
dc.identifier.uri | https://doi.org/10.1016/j.jnma.2017.05.007 | |
dc.identifier.uri | https://www.sciencedirect.com/science/article/abs/pii/S0027968417300287 | |
dc.identifier.uri | http://hdl.handle.net/11452/34195 | |
dc.identifier.volume | 110 | tr_TR |
dc.identifier.wos | 000432909100008 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Natl Med Assoc | en_US |
dc.relation.collaboration | Sanayi | tr_TR |
dc.relation.journal | Journal of the National Medical Association | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | General & internal medicine | en_US |
dc.subject | Hypothyroidism | en_US |
dc.subject | Levothyroxine | en_US |
dc.subject | Malabsorption | en_US |
dc.subject | Neurologic manifestations | en_US |
dc.subject | Thyroxine absorption | en_US |
dc.subject | Pseudomalabsorption | en_US |
dc.subject | Malabsorption | en_US |
dc.subject | Replacement | en_US |
dc.subject | Patient | en_US |
dc.subject | Disease | en_US |
dc.subject.emtree | Acetylsalicylic acid | en_US |
dc.subject.emtree | Levothyroxine | en_US |
dc.subject.emtree | Liothyronine | en_US |
dc.subject.emtree | Thyrotropin | en_US |
dc.subject.emtree | Thyroxine | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Aphasia | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood pressure | en_US |
dc.subject.emtree | Body mass | en_US |
dc.subject.emtree | Body temperature | en_US |
dc.subject.emtree | Body weight gain | en_US |
dc.subject.emtree | Case report | en_US |
dc.subject.emtree | Clinical article | en_US |
dc.subject.emtree | Drug megadose | en_US |
dc.subject.emtree | Drug safety | en_US |
dc.subject.emtree | Dry skin | en_US |
dc.subject.emtree | Fatigue | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Free thyroxine index | en_US |
dc.subject.emtree | Heart rate | en_US |
dc.subject.emtree | Hemiparesis | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Hypertension | en_US |
dc.subject.emtree | Hypothyroidism | en_US |
dc.subject.emtree | Menstruation | en_US |
dc.subject.emtree | Physical examination | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Side effect | en_US |
dc.subject.emtree | Thyroid function test | en_US |
dc.subject.emtree | Thyrotropin blood level | en_US |
dc.subject.emtree | Transient ischemic attack | en_US |
dc.subject.emtree | Treatment response | en_US |
dc.subject.emtree | Visual impairment | en_US |
dc.subject.emtree | Hypothyroidism | en_US |
dc.subject.emtree | Intestine absorption | en_US |
dc.subject.emtree | Intramuscular drug administration | en_US |
dc.subject.emtree | Malabsorption | en_US |
dc.subject.emtree | Metabolism | en_US |
dc.subject.emtree | Oral drug administration | en_US |
dc.subject.emtree | Pathology | en_US |
dc.subject.emtree | Pathophysiology | en_US |
dc.subject.emtree | Procedures | en_US |
dc.subject.emtree | Thyroid tumor | en_US |
dc.subject.emtree | Thyroidectomy | en_US |
dc.subject.emtree | Treatment outcome | en_US |
dc.subject.mesh | Administration, oral | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hypothyroidism | en_US |
dc.subject.mesh | Injections, intramuscular | en_US |
dc.subject.mesh | Intestinal absorption | en_US |
dc.subject.mesh | Malabsorption syndromes | en_US |
dc.subject.mesh | Thyroid cancer, papillary | en_US |
dc.subject.mesh | Thyroid neoplasms | en_US |
dc.subject.mesh | Thyroidectomy | en_US |
dc.subject.mesh | Thyroxine | en_US |
dc.subject.mesh | Treatment outcome | en_US |
dc.subject.scopus | Levothyroxine Sodium; Hypothyroidism; Thyrotropin | en_US |
dc.subject.wos | Medicine, general & internal | en_US |
dc.title | Is parenteral levothyroxine therapy safe in intractable hypothyroidism? | en_US |
dc.type | Article | |
dc.wos.quartile | Q4 | en_US |
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