After the eradication of helicobacter pylori infection, relapse is a serious problem in Turkey

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dc.contributor.authorBesisk, Fatih
dc.contributor.authorDemir, Kadir
dc.contributor.authorMungan, Zeynel
dc.contributor.authorKaymakoğlu, Sabahattin
dc.contributor.authorBozta, Güngör
dc.contributor.authorÇakaloğlu, Yilmaz
dc.contributor.authorYeğinsu, Oktay
dc.contributor.authorÖkten, Atilla
dc.contributor.buuauthorGürel, Selim
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Gastroenteroloji Anabilim Dalı.tr_TR
dc.date.accessioned2021-07-05T11:20:52Z
dc.date.available2021-07-05T11:20:52Z
dc.date.issued1999
dc.description.abstractEradication of Helicobacter pylori (Hp) infection is strongly recommended in duodenal and gastric ulcer. In developed countries the recurrence rate is low; however, in Turkey, the Hp recurrence rate is suspected to be high as the prevalence of Hp infection is-as high as 70-80% in the asymptomatic population. We planned this study to determine the relapse rate of Hp infection after successful eradication therapy in Turkey. Fifty-two cases including 24 patients with duodenal ulcer and 28 patients with nonulcer dyspepsia were examined in this study. The eradication regimen was omeprazole 20 mg twice daily, clarithromycin 500 mg twice daily, and metronidazole 500 mg three times a day for 1 week. All patients underwent upper gastrointestinal tract endoscopy. At least four samples from antrum and corpus were taken to enable histologic diagnosis of Hp infection. After the eradication therapy, endoscopy was repeated at 1, 3, 6, and 12 months, and Hp-positive patients were dropped from study. With the use of this regimen, the Hp eradication rate was 92.3% (48/52). After the eradication of Hp infection, relapse rates were 6.97%, 27.5%, and 11.11% at 3, 6, and 12 months, respectively. The cumulative relapse rate for 1 year was 41.46%. The results of this study revealed that after the eradication of Hp infection, recurrence is encountered very often as a problem in Turkey. We concluded that hygienic and environmental factors can affect these high relapse rates.en_US
dc.identifier.citationGürel, S. vd. (1999). "After the eradication of helicobacter pylori infection, relapse is a serious problem in Turkey". Journal of Clinical Gastroenterology, 28(3), 241-244.en_US
dc.identifier.endpage244tr_TR
dc.identifier.issn0192-0790
dc.identifier.issue3tr_TR
dc.identifier.pubmed10192611tr_TR
dc.identifier.scopus2-s2.0-0033038349tr_TR
dc.identifier.startpage241tr_TR
dc.identifier.urihttps://doi.org/10.1097/00004836-199904000-00011
dc.identifier.urihttps://europepmc.org/article/med/10192611
dc.identifier.urihttp://hdl.handle.net/11452/21066
dc.identifier.volume28tr_TR
dc.identifier.wos000079294100011tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalJournal of Clinical Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastroenterology & hepatologyen_US
dc.subjectHelicobacter pylori eradicationen_US
dc.subjectRelapseen_US
dc.subjectDuodenal-ulceren_US
dc.subjectRecrudescenceen_US
dc.subjectReinfectionen_US
dc.subject.wosGastroenterology & hepatologyen_US
dc.titleAfter the eradication of helicobacter pylori infection, relapse is a serious problem in Turkeyen_US
dc.typeArticle

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