The effects on metabolism of glucosinolates and theirs hydrolysis products

dc.contributor.buuauthorPolat, Umit
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi.tr_TR
dc.date.accessioned2021-03-08T07:42:38Z
dc.date.available2021-03-08T07:42:38Z
dc.date.issued2010
dc.description.abstractGlucosinolates in the nutrition are very important molecules and widely found in Brassicaceae species (brussels sprouts, Dijon mustard, broccoli, cress etc.). Depending on the amount of these kinds of vegetables consumed by humans and animals, some positive or negative metabolic effects of this molecule may occur. Chemically GLS’s are the anticarsinogenic molecules that increase the antioxidan effect, the antibiotic activity and induced the phase-II detoxification enzymes. However, there are the studies shown that I3C, a member of the hydrolysis products of GLS’s, stimulated and inhibited the carsinogenesis. While the low doses of GLS's may be the antiostrogenic effect, the high doses can an estrogen agonist. Due to the lack of scientific data regarding the dose of the molecule that induces favorable and unfavorable effects on the target tissue, our knowledge of this molecule on induction of potential carcinogenic/anticarcinogenic, estrogenic/antiestrogenic, antibiotic effects as well as on regulation of energy balance remains largely insufficient. They constitute the liver, thyroid, rectum abnormalities, and deterioration in the development and reproductive performance. Especially the biological effects, that defines the need to study GLS bioavailability, critically assess the current state of the art on GLS bioavailability, indicate human and animal data on important individual compounds and structural groups, and give recommendations for future research.en_US
dc.identifier.citationPolat, U. (2010). "The effects on metabolism of glucosinolates and theirs hydrolysis products". Journal of Biological and Environmental Sciences, 4(10), 39-42.tr_TR
dc.identifier.endpage42tr_TR
dc.identifier.issn1307-9530
dc.identifier.issn1308-2019
dc.identifier.issue10tr_TR
dc.identifier.startpage39tr_TR
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/497790
dc.identifier.urihttp://hdl.handle.net/11452/17214
dc.identifier.volume4tr_TR
dc.language.isoenen_US
dc.publisherUludağ Üniversitesitr_TR
dc.relation.journalJournal of Biological and Environmental Sciencestr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBrassicaceaeen_US
dc.subjectCanceren_US
dc.subjectMyrosinaseen_US
dc.subjectGlucosinolateen_US
dc.titleThe effects on metabolism of glucosinolates and theirs hydrolysis productsen_US
dc.typeArticleen_US

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