Adiponectin, leptin, nitric oxide, and C-reactive protein levels in kidney transplant recipients: Comparison with the hemodialysis and chronic renal failure

Simple item page
dc.contributor.buuauthorOcak, Nihal
dc.contributor.buuauthorDirican, Melahat
dc.contributor.buuauthorErsoy, Alparslan
dc.contributor.buuauthorSarandöl, Emre
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-0710-0923tr_TR
dc.contributor.orcid0000-0002-2593-7196tr_TR
dc.contributor.researcheridAAH-5054-2021tr_TR
dc.contributor.researcheridABE-1716-2020tr_TR
dc.contributor.scopusid23989248600tr_TR
dc.contributor.scopusid6601919847tr_TR
dc.contributor.scopusid35612977100tr_TR
dc.contributor.scopusid55943324800tr_TR
dc.date.accessioned2022-11-28T11:48:33Z
dc.date.available2022-11-28T11:48:33Z
dc.date.issued2016-08-20
dc.description.abstractBackground: Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in patients with chronic kidney disease (CKD) including kidney transplant recipients (KTR). Secondary lipid metabolism disorders, endothelial dysfunction, and inflammation enhance the risk of CVD development in these patients. The aim of the present study was to investigate the lipid profile, adiponectin, leptin, nitric oxide (NO), and high sensitivity C-reactive protein (hs-CRP) levels in KTR and to compare these parameters with those of the patients with chronic renal failure (CRF), hemodialysis (HD) patients, and healthy controls.Methods: Serum adiponectin and leptin levels were measured by radioimmunoassay; hs-CRP was determined immunoturbidimetrically. Determination of NO was based on the Griess reaction.Results: Compared with the control group, serum NO and adiponectin levels were significantly higher in the KTR, CRF, and HD groups; hs-CRP levels were significantly higher in the KTR and HD groups; leptin levels were significantly higher in the KTR. In addition, serum NO level was significantly higher in the KTR compared to CRF cases. Adiponectin correlated positively with high density lipoprotein-cholesterol in the control and patient groups. A positive correlation was observed between hs-CRP and NO in the KTR and the patients with CRF. Serum adiponectin levels were inversely correlated with hs-CRP and leptin in the HD group.Conclusion: KTR suffer from inflammation and accompanying changes in levels of adipocytokines and NO which contribute to the increased risk of CVD in these patients.en_US
dc.identifier.citationOcak, N. vd. (2016). "Adiponectin, leptin, nitric oxide, and C-reactive protein levels in kidney transplant recipients: cComparison with the hemodialysis and chronic renal failure". Renal Failure, 38(10), 1639-1646.en_US
dc.identifier.endpage1646tr_TR
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue10tr_TR
dc.identifier.pubmed27764985tr_TR
dc.identifier.scopus2-s2.0-84992107620tr_TR
dc.identifier.startpage1639tr_TR
dc.identifier.urihttps://doi.org/10.1080/0886022X.2016.1229965
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/0886022X.2016.1229965
dc.identifier.urihttp://hdl.handle.net/11452/29596
dc.identifier.volume38tr_TR
dc.identifier.wos000392430900012tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.bap2010/2tr_TR
dc.relation.journalRenal Failureen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUrology & nephrologyen_US
dc.subjectKidney transplantationen_US
dc.subjectNitric oxideen_US
dc.subjectC-reactive proteinen_US
dc.subjectAdiponectinen_US
dc.subjectLeptinen_US
dc.subjectCoronary-artery-diseaseen_US
dc.subjectMetabolic risk-factorsen_US
dc.subjectPlasma adiponectinen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectCardiovascular-diseaseen_US
dc.subjectLipid-metabolismen_US
dc.subjectAdipose-tissueen_US
dc.subjectSerum leptinen_US
dc.subjectAtherosclerosisen_US
dc.subjectHomocysteineen_US
dc.subject.emtreeAdiponectinen_US
dc.subject.emtreeApolipoprotein A1en_US
dc.subject.emtreeApolipoprotein Ben_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeCholesterolen_US
dc.subject.emtreeCreatinineen_US
dc.subject.emtreeCyclosporinen_US
dc.subject.emtreeHigh density lipoprotein cholesterolen_US
dc.subject.emtreeHigh sensitivity c reactive proteinen_US
dc.subject.emtreeLeptinen_US
dc.subject.emtreeLipoprotein Aen_US
dc.subject.emtreeLow density lipoprotein cholesterolen_US
dc.subject.emtreeNitrateen_US
dc.subject.emtreeNitric oxideen_US
dc.subject.emtreeNitriteen_US
dc.subject.emtreeTacrolimusen_US
dc.subject.emtreeTriacylglycerolen_US
dc.subject.emtreeUnclassified drugen_US
dc.subject.emtreeUreaen_US
dc.subject.emtreeAdiponectinen_US
dc.subject.emtreeBiological markeren_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeLeptinen_US
dc.subject.emtreeNitric oxideen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChronic kidney failureen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeClinical studyen_US
dc.subject.emtreeConservative treatmenten_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGraft recipienten_US
dc.subject.emtreeHemodialysisen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHypertensionen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProtein blood levelen_US
dc.subject.emtreeRadioimmunoassayen_US
dc.subject.emtreeBlooden_US
dc.subject.emtreeCardiovascular diseasesen_US
dc.subject.emtreeCase control studyen_US
dc.subject.emtreeHemodialysisen_US
dc.subject.emtreeInflammationen_US
dc.subject.emtreeKidney failure, chronicen_US
dc.subject.emtreeKidney transplantationen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreeTurkeyen_US
dc.subject.meshAdiponectinen_US
dc.subject.meshAdulten_US
dc.subject.meshBiomarkersen_US
dc.subject.meshC-reactive proteinen_US
dc.subject.meshCardiovascular diseasesen_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInflammationen_US
dc.subject.meshKidney failure, chronicen_US
dc.subject.meshKidney transplantationen_US
dc.subject.meshLeptinen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNitric oxideen_US
dc.subject.meshRenal dialysisen_US
dc.subject.meshTransplant recipientsen_US
dc.subject.meshTurkeyen_US
dc.subject.scopusImpotence; Sexual Dysfunction; Chronic Kidney Failureen_US
dc.subject.wosUrology & nephrologyen_US
dc.titleAdiponectin, leptin, nitric oxide, and C-reactive protein levels in kidney transplant recipients: Comparison with the hemodialysis and chronic renal failureen_US
dc.typeArticle
dc.wos.quartileQ4en_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Ocak_vd_2016.pdf
Size:
1.04 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Web of Science
Scopus