Chronic amyloid arthropathy and increased serum amyloid levels in brown layers

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dc.contributor.authorSevimli, Alper
dc.contributor.authorUğuz, Cevdet
dc.contributor.buuauthorAlasonyalılar, Aylin
dc.contributor.buuauthorMısırlıoğlu, Deniz
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı.tr_TR
dc.contributor.scopusid8529950700tr_TR
dc.contributor.scopusid6507455482tr_TR
dc.date.accessioned2021-12-06T06:57:45Z
dc.date.available2021-12-06T06:57:45Z
dc.date.issued2006
dc.description.abstractSerum amyloid-A (SAA) levels were investigated in chickens with experimentally induced amyloid arthropathy in comparison with healthy Counterparts. Forty-eight 5-week-old chickens were allocated into two equally numbered groups. Enterococcus faecalis was injected intraarticularly at concentrations of 10(9) cfu/ml, to induce amyloid arthropathy in one of the groups, whereas the other one was kept as a control and injected intraarticularly only with 0.9% NaCl (1 ml). All the chickens were necropsied at the 13(th) week after the injections. Joint sections were examined histopathologically and immunohistochemically. Blood samples were collected and SAA levels were determined by ELISA. Amyloid accumulation in joints was only seen in the experimental group (18/24). The SAA levels found were 154 +/- 20 ng/ml and 419 +/- 27 ng/ml in the control and experimental groups, respectively, and the differences were highly significant at (P < 0.001). In conclusion, SAA plasma concentrations are influenced by amyloid arthropathy. Consequently, SAA may be a sensitive variable to assess the physical welfare in chicks; and increases in these values can be suggestive of chronic inflammatory processes, including amyloid arthropathy.en_US
dc.identifier.citationAlasonyalılar, A. vd. (2006). ''Chronic amyloid arthropathy and increased serum amyloid levels in brown layers''. Bulletin of the Veterinary Institute in Pulawy, 50(4), 557-560.en_US
dc.identifier.endpage560tr_TR
dc.identifier.issn0042-4870
dc.identifier.issue4tr_TR
dc.identifier.scopus2-s2.0-33847767060tr_TR
dc.identifier.startpage557tr_TR
dc.identifier.urihttp://hdl.handle.net/11452/22997
dc.identifier.volume50tr_TR
dc.identifier.wos000243278300027tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherNatl Veterinary Research Instituteen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalBulletin of the Veterinary Institute in Pulawyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChickensen_US
dc.subjectAmyloid arthropathyen_US
dc.subjectAmyloiden_US
dc.subjectGallus gallusen_US
dc.subjectEnterococcus faecalisen_US
dc.subject.scopusSerum Amyloid A Protein; Amyloidosis; Amyloid Enhancing Factoren_US
dc.subject.wosVeterinary sciencesen_US
dc.titleChronic amyloid arthropathy and increased serum amyloid levels in brown layersen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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