Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases

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dc.contributor.authorBıyıklı, Zeynep
dc.contributor.buuauthorUslusoy, Hüseyin Saadettin
dc.contributor.buuauthorNak, Selim Giray
dc.contributor.buuauthorGülten, Macit
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Gastroenteroloji Anabilim Dalı.tr_TR
dc.contributor.scopusid8886940400tr_TR
dc.contributor.scopusid6603336505tr_TR
dc.contributor.scopusid6603629209tr_TR
dc.date.accessioned2022-01-25T11:12:25Z
dc.date.available2022-01-25T11:12:25Z
dc.date.issued2009-03-07
dc.description.abstractAIM: To investigate the histologic features of the liver in nonalcoholic fatty liver disease (NAFLD) cases according to the presence of metabolic syndrome or its individual components. METHODS: We enrolled 81 patients (40 male, 41 female) who were diagnosed with fatty liver by ultrasonographic scan and fulfilled the inclusion criteria. First anamnesis, anthropometric, clinical, laboratory and imaging features of all participants were recorded and then liver biopsy was performed after gaining consent from patients. Diagnosis of metabolic syndrome was dependent on patients having 3 or more out of 5 risk criteria defined by the WHO. Biopsy specimens were assessed according to Brunt et al's classification. RESULTS: Sixty-nine of the 81 patients had nonalcoholic steatohepatitis (NASH), 11 had simple fatty liver and 1 had cirrhosis according to histologic evaluation. Comparisons were made between two groups of NASH patients, those with and without metabolic syndrome. We did not detect statistically significant differences in liver histology between NASH patients with and without metabolic syndrome. CONCLUSION: NASH can progress without metabolic risk factors or the presence of metabolic syndrome.en_US
dc.identifier.citationUslusoy, H. S. vd. (2009). "Liver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease cases". World Journal of Gastroenterology, 15(9), 1093-1098.en_US
dc.identifier.endpage1098tr_TR
dc.identifier.issn1007-9327
dc.identifier.issue9tr_TR
dc.identifier.pubmed19266602tr_TR
dc.identifier.scopus2-s2.0-65549088089tr_TR
dc.identifier.startpage1093tr_TR
dc.identifier.urihttps://doi.org/10.3748/wjg.15.1093
dc.identifier.urihttps://www.wjgnet.com/1007-9327/full/v15/i9/1093.htm
dc.identifier.urihttp://hdl.handle.net/11452/24286
dc.identifier.volume15tr_TR
dc.identifier.wos000264152300010tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Groupen_US
dc.relation.collaborationYurt içitr_TR
dc.relation.journalWorld Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiver histologyen_US
dc.subjectMetabolic risk factorsen_US
dc.subjectMetabolic syndromeen_US
dc.subjectNonalcoholic steatohepatitisen_US
dc.subjectPatty liveren_US
dc.subjectInsulin-resistanceen_US
dc.subjectSteatohepatitisen_US
dc.subjectFibrosisen_US
dc.subjectComplicationsen_US
dc.subjectAssociationen_US
dc.subjectDefinitionen_US
dc.subjectPredictorsen_US
dc.subjectSeverityen_US
dc.subjectSpectrumen_US
dc.subjectNashen_US
dc.subjectGastroenterology & hepatologyen_US
dc.subject.emtreeAlanine aminotransferaseen_US
dc.subject.emtreeAlkaline phosphataseen_US
dc.subject.emtreeAspartate aminotransferaseen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAnamnesisen_US
dc.subject.emtreeAnthropometryen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeClinical examinationen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeEchographyen_US
dc.subject.emtreeFatty liveren_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHuman tissueen_US
dc.subject.emtreeImage analysisen_US
dc.subject.emtreeInformed consenten_US
dc.subject.emtreeLaboratory testen_US
dc.subject.emtreeLiver biopsyen_US
dc.subject.emtreeLiver cirrhosisen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical recorden_US
dc.subject.emtreeMetabolic syndrome Xen_US
dc.subject.emtreeNonalcoholic fatty liveren_US
dc.subject.emtreeRisk assessmenten_US
dc.subject.emtreeSex differenceen_US
dc.subject.emtreeBiopsyen_US
dc.subject.emtreeBlooden_US
dc.subject.emtreeBody massen_US
dc.subject.emtreeDiabetes mellitusen_US
dc.subject.emtreeDisease courseen_US
dc.subject.emtreeFatty liveren_US
dc.subject.emtreeGlucose tolerance testen_US
dc.subject.emtreeLiveren_US
dc.subject.emtreeLiver cirrhosistren_US
dc.subject.emtreeObesityen_US
dc.subject.emtreePathologyen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeWaist hip ratioen_US
dc.subject.meshAlanine transaminaseen_US
dc.subject.meshAlkaline phosphataseen_US
dc.subject.meshAspartate aminotransferasesen_US
dc.subject.meshBiopsyen_US
dc.subject.meshBody mass indexen_US
dc.subject.meshDiabetes complicationsen_US
dc.subject.meshDiabetes mellitusen_US
dc.subject.meshDisease progressionen_US
dc.subject.meshFatty liveren_US
dc.subject.meshFemaleen_US
dc.subject.meshGlucose tolerance testen_US
dc.subject.meshHumansen_US
dc.subject.meshLiveren_US
dc.subject.meshLiver cirrhosisen_US
dc.subject.meshMaleen_US
dc.subject.meshMetabolic syndrome Xen_US
dc.subject.meshObesityen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshWaist-hip ratioen_US
dc.subject.scopusFatty Liver; Proton Density (Concentration); Keratin-18en_US
dc.subject.wosGastroenterology & hepatologyen_US
dc.titleLiver histology according to the presence of metabolic syndrome in nonalcoholic fatty liver disease casesen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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