Bir kedide rastlanılan hiperşilomikronemi, feline infectious peritonıtıs (fıp) ve psoydoşiloz efuzyon olgusu

Abstract

A one year old male, domestic cat was referred for examination at the Veterinary Hospital of the Faculty ofVeterinary Medicine ofUludag University, presented with abdominal distention. Clinical examination, hematology, microscobical and biochemical analysis of abdominal fluid were performed. He had nQnregenerative aneamia, neutrophilic leukocytosis, relative lymphopenia and pseudochylous effusion. Lactascent serum was observed, he had hypertriglisedimia; chylomicron and Lipoprotein Lipaz Activity tests were positive. Serum was evaluated for FeLV, FIV and FIP serologically and PCR analysis of the serum and effusion were performed. Positive results were obtained for FIP. Histopathology revealed severe serosal and capsular pyogranulamatous inflammation. Histochemistry depicted fine cholesterol crystals, saturated lipids, ceroid pigments within the foam cells and macrophages.

Bu olgu raporunun materyalini abdominal dolgunluk şikayeti ile Uludag Universitesi Veteriner Fakultesi kliniklerine getirilen I yaşıt, yerli, erkek kedi oluşturdu. Klinik muayene ve rutin hematolojiyi takiben abdomi nal sıvının mikroskobik ve biyokimyasal analizleri yapıldı. Nonregeneratif anemi, notrofilik lokositoz, relatiflenfopeni ve psoydoşiloz efuzyon oldugu belirlenen kediye ail kanzn bulanzk oldugu dikkat çekti. Hipertrigliseridemt saptanan kedide şilomikron ve Lipoprotein Lipaz (LPL) Aktivite testi pozitif bulundu. FeLV ve FJV negatif olan kedi, serum ve peritoneal sıvıda yapzlan PCR analizleri sonucunda FIP pozitif bulundu. Histopatolojik muayene sonucunda FIP'a ozgil şiddetli serozal ve kapsuler pyogranulamatoz yangz, histokimyasal boyamalar sonucunda hipersilomikronemiyi belgeleyen ince kolesterol kristalleri, doymuş lipidler ve kopilk hucreleri içerisinde seroid pigmentler ve makrofajlar gozlendi.