Androgens and sexual dysfunction in naturally and surgically menopausal women
dc.contributor.buuauthor | Alarslan, Demet | |
dc.contributor.buuauthor | Sarandol, Aslı | |
dc.contributor.buuauthor | Cengiz, Candan | |
dc.contributor.buuauthor | Develioǧlu, Osman H. | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Psikiyatri Anabilim Dalı. | tr_TR |
dc.contributor.scopusid | 50260943700 | tr_TR |
dc.contributor.scopusid | 14020405100 | tr_TR |
dc.contributor.scopusid | 6701513182 | tr_TR |
dc.contributor.scopusid | 6701315440 | tr_TR |
dc.date.accessioned | 2022-01-07T12:40:39Z | |
dc.date.available | 2022-01-07T12:40:39Z | |
dc.date.issued | 2011-08 | |
dc.description.abstract | Aim: To evaluate the influence of surgical versus natural menopause on sexual dysfunction, and the role of androgens in that context. Material & Methods: Sexual functioning and androgen levels were studied in 35 surgically and 83 naturally menopausal women. Sexual dysfunction was defined as a total score of less than 23 on the Female Sexual Function Index. Results: Sexual dysfunction was significantly more common in surgically than in naturally menopausal women (65.7% vs 44.6%; P = 0.036). The mean total testosterone level in women with sexual dysfunction was significantly lower than that in their counterparts (49.3 +/- 21.0 vs 58.8 +/- 23.6 ng/mL; P = 0.022). On the other hand, androgen levels did not differ significantly between surgically and naturally menopausal women. Androstenedione (B = 2.253; P = 0.039) and dehydroepiandrosterone sulfate levels (B = 0.222; P < 0.001), and time from menopause (B = -0.064; P = 0.040) were found to be independent determinants of total testosterone levels. While the duration of menopause was significantly longer in surgically menopausal women, this co-factor was not an independent predictor of sexual dysfunction. Logistic regression analysis proved mode of menopause and total testosterone levels to be the only two independent determinants of sexual dysfunction. Conclusions: Our findings suggest that while surgical menopause is detrimental to sexual functioning by itself, lower testosterone levels are predictive of sexual dysfunction, especially in naturally menopausal women. | en_US |
dc.identifier.citation | Alarslan, D. vd. (2011). "Androgens and sexual dysfunction in naturally and surgically menopausal women". Journal of Obstetrics and Gynaecology Research, 37(8), 1027-1034. | en_US |
dc.identifier.endpage | 1034 | tr_TR |
dc.identifier.issn | 1341-8076 | |
dc.identifier.issn | 1447-0756 | |
dc.identifier.issue | 8 | tr_TR |
dc.identifier.pubmed | 21481089 | tr_TR |
dc.identifier.scopus | 2-s2.0-80052709702 | tr_TR |
dc.identifier.startpage | 1027 | tr_TR |
dc.identifier.uri | https://doi.org/10.1111/j.1447-0756.2010.01479.x | |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/21481089/ | |
dc.identifier.uri | http://hdl.handle.net/11452/23932 | |
dc.identifier.volume | 37 | tr_TR |
dc.identifier.wos | 000293234700010 | tr_TR |
dc.indexed.pubmed | Pubmed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.relation.journal | Journal of Obstetrics and Gynaecology Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Obstetrics & gynecology | en_US |
dc.subject | Androgen | en_US |
dc.subject | Menopause | en_US |
dc.subject | Sexual dysfunction | en_US |
dc.subject | Surgical | en_US |
dc.subject | Health-related quality | en_US |
dc.subject | Postmenopausal ovary | en_US |
dc.subject | United-states | en_US |
dc.subject | Hysterectomy | en_US |
dc.subject | Testosterone | en_US |
dc.subject | Oophorectomy | en_US |
dc.subject | Estrogen | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Estradiol | en_US |
dc.subject | Life | en_US |
dc.subject.emtree | Androstenedione | en_US |
dc.subject.emtree | Estradiol | en_US |
dc.subject.emtree | Prasterone sulfate | en_US |
dc.subject.emtree | Prolactin | en_US |
dc.subject.emtree | Sex hormone binding globulin | en_US |
dc.subject.emtree | Testosterone | en_US |
dc.subject.emtree | Abdominal hysterectomy | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Androgen blood level | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Comparative study | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Female sexual dysfunction | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Logistic regression analysis | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Menopause | en_US |
dc.subject.emtree | Natural menopause | en_US |
dc.subject.emtree | Salpingooophorectomy | en_US |
dc.subject.emtree | Scoring system | en_US |
dc.subject.emtree | Sexual function | en_US |
dc.subject.emtree | Surgical menopause | en_US |
dc.subject.emtree | Vaginal hysterectomy | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Androgens | en_US |
dc.subject.mesh | Cross-sectional studies | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Hysterectomy | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Ovariectomy | en_US |
dc.subject.mesh | Postmenopause | en_US |
dc.subject.mesh | Prevalence | en_US |
dc.subject.mesh | Sexual dysfunction, physiological | en_US |
dc.subject.mesh | Testosterone congeners | en_US |
dc.subject.mesh | Turkey | en_US |
dc.subject.scopus | Psychosexual Disorder; Flibanserin; Bremelanotide | en_US |
dc.subject.wos | Obstetrics & gynecology | en_US |
dc.title | Androgens and sexual dysfunction in naturally and surgically menopausal women | en_US |
dc.type | Article | |
dc.wos.quartile | Q4 | en_US |
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