Kronik renal yetmezlikte balık yağının lipit metabolizması üzerine etkileri
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Date
1984
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Uludağ Üniversitesi
Abstract
Hemodiyaliz programına alınmış, 3 'ü kadın, 7 'si erkek kronik renal yetmezlikteki gönüllü hastalar üzerinde, balık yağının lipit metabolizması üzerine etkileri incelendi. Balık yağı uygulamasından önce (BYÖ), yüksek dansiteli lipoprotein (HDL) kolesterolü % 41.3 :1:1.5 mg, balık yağı uygulamasından sonra (BYS) % 34.2-2.4 mg olarak bulundu (p < 0.02). Lipoprotein elektroforezi de BY<J % 29.76. ± 2.4 olan alpha lipoproteins, BYS % 23.51. ± 1 .7 olarak bulundu (p < 0.0 1). Bı,ma karşın BY<J % 55.8 ± 3.2 olan (3-lipoproteins, BYS % 67.7 ± 4 idi (p < 0.02). BYS HDL apoprotein A -I'de anlamlı olmayan bir düşme, HDL-apoprotein A-II de ise önemli bir azalma tespit edildi (p < 0.01). Kronik renal yetmezlik te balık yağının aterojenik risk artırıcı yönde rol oynadığı sonucuna varıldı.
The effects of fish oil on the lipid metabolism were investigated in 3 female and 7 male chronic renal patients who have volunteered and who were receiving maintenance hemodialysis. High density lipoprotein (HDL) cholesterol was % 41.3 - 1,5 mg before fish oil ingestion (BFO) and % 34.2 ± 2.4 mg a{ter fish oil ingestion (AFO), (p < 0.02). In the lipoprotein electrophoresis a-lipoproteins were % 29.76 ± 2.4 BFO and 23.51. ± 1.7 AFO (p < 0.01). On the contrary lipoproteins were % 55.8- 3.2 BFO and 67.7 ± 4 AFO (p < 0.02). There was an insignificant decrease in the HDL-apoprotein A-l and there was a significant decrease in the HDL·apoprotein A-ll AFO, (p .< 0.01). Fish oil in chronic renal failure appears to increase atherogenic risk factors as a result of our findings.
The effects of fish oil on the lipid metabolism were investigated in 3 female and 7 male chronic renal patients who have volunteered and who were receiving maintenance hemodialysis. High density lipoprotein (HDL) cholesterol was % 41.3 - 1,5 mg before fish oil ingestion (BFO) and % 34.2 ± 2.4 mg a{ter fish oil ingestion (AFO), (p < 0.02). In the lipoprotein electrophoresis a-lipoproteins were % 29.76 ± 2.4 BFO and 23.51. ± 1.7 AFO (p < 0.01). On the contrary lipoproteins were % 55.8- 3.2 BFO and 67.7 ± 4 AFO (p < 0.02). There was an insignificant decrease in the HDL-apoprotein A-l and there was a significant decrease in the HDL·apoprotein A-ll AFO, (p .< 0.01). Fish oil in chronic renal failure appears to increase atherogenic risk factors as a result of our findings.
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Keywords
Kronik renal yetmezliği, Balık yağı, Lipit metabolizması, Chronic renal failure, Fish oil, Lipid metabolism
Citation
Yurtkuran, M. vd. (1984). ''Kronik renal yetmezlikte balık yağının lipit metabolizması üzerine etkileri''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 11(1), 111-115.