Audiological abnormalities in patients with vitiligo

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dc.contributor.buuauthorAydoğan, Kenan
dc.contributor.buuauthorTuran, O. F.
dc.contributor.buuauthorOnart, Selçuk
dc.contributor.buuauthorKaradoğan, Serap K.
dc.contributor.buuauthorTunalı, Şükran
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı/Baş Boyun Cerrahisi.tr_TR
dc.contributor.orcid0000-0002-0193-1128tr_TR
dc.contributor.researcheridAAH-6216-2021tr_TR
dc.date.accessioned2021-09-14T08:32:41Z
dc.date.available2021-09-14T08:32:41Z
dc.date.issued2006
dc.description.abstractBackground. Accumulating evidence suggests that vitiligo is a systemic disease affecting the entire pigmentary system. Aim. To investigate the subclinical abnormalities of melanin-containing cellular elements of the auditory system in patients with vitiligo. Methods. We studied the conventional audiometric investigations and brainstem auditory evoked responses (BAERs) of 57 active patients with vitiligo and 50 healthy human subjects. The I, III and V latencies, and I-III, III-V and I-V interpeak latencies (IPL) between the groups were compared. Results. A mild degree of sensorineural hypoacusis was found in eight patients with vitiligo (14%), whereas no controls demonstrated abnormal audiological results (P = 0.006). A statistically significant increase in both ears of the third peak latency (P = 0.02, P = 0.01, respectively) and IPL I-III (P = 0.04, P = 0.008, respectively), and a significant increase of the fifth peak latency in the right ear (P = 0.04) were found, compared with controls, but no differences were found for other latencies and IPLs. Conclusions. Melanin may play a significant role in the establishment and/or maintenance of the structure and function of the auditory system and may modulate the transduction of the auditory stimuli by the inner ear.en_US
dc.identifier.citationAydoğan, K. vd. (2006). ''Audiological abnormalities in patients with vitiligo''. Clinical and Experimental Dermatology, 31(1), 110-113.en_US
dc.identifier.endpage113tr_TR
dc.identifier.issn0307-6938
dc.identifier.issn1365-2230
dc.identifier.issue1tr_TR
dc.identifier.pubmed16309498tr_TR
dc.identifier.scopus2-s2.0-33646102236tr_TR
dc.identifier.startpage110tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2005.02004.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1365-2230.2005.02004.x
dc.identifier.urihttp://hdl.handle.net/11452/21930
dc.identifier.volume31tr_TR
dc.identifier.wos000233529300031tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileytr_TR
dc.relation.journalClinical and Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDermatologyen_US
dc.subjectMelaninen_US
dc.subjectHearingen_US
dc.subjectDisturbancesen_US
dc.subjectMelanocytesen_US
dc.subjectHuman-brainen_US
dc.subjectStria vascularisen_US
dc.subjectEvoked-potentialsen_US
dc.subjectInner-earen_US
dc.subject.scopusVitiligo; Otoacoustic Emissions; Pure Tone Audiometryen_US
dc.subject.wosDermatologyen_US
dc.titleAudiological abnormalities in patients with vitiligoen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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