Comparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trial

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dc.contributor.buuauthorArmaǧan, Erol
dc.contributor.buuauthorKocabaş, Egemen
dc.contributor.buuauthorKöksal, Özlem
dc.contributor.buuauthorŞimşek, Gözde
dc.contributor.buuauthorBal, Haldun
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Acil Tıp Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kan ve Kan Ürünleri Merkezi.tr_TR
dc.contributor.orcid0000-0003-2271-5659tr_TR
dc.contributor.researcheridAAH-8846-2021tr_TR
dc.contributor.researcheridAAK-8332-2020tr_TR
dc.contributor.scopusid6506464232tr_TR
dc.contributor.scopusid55317360100tr_TR
dc.contributor.scopusid23389880200tr_TR
dc.contributor.scopusid57225727701tr_TR
dc.contributor.scopusid57198099466tr_TR
dc.date.accessioned2022-02-15T09:37:44Z
dc.date.available2022-02-15T09:37:44Z
dc.date.issued2012-05
dc.description.abstractObjective: This study aimed to compare the efficacies of two different topical anesthetic agents and placebo in the reduction of the pain observed during intravenous (IV) cannulation. Methods: Study enrolled a total of 129 healthy male donors and IV cannulation was performed to antecubital region. The donors were assigned into three groups. Prilocaine-lidocaine mixture cream (E), lidocaine spray (X) and Placebo cream (P) were given to patients. After the administration the donors were waited for approximately 45 minutes. The pain experienced by the donors after the insertion of 16 gauge cannula in arms was recorded as "pain experienced at minute 0, 5 and 15" on 100 mm visual analog scale (VAS). Results: In the first group, there was no significant difference between mean VAS scores recorded after the administration of prilocainelidocaine mixture cream and lidocaine spray before IV cannulation. Mean VAS value was 9.1 mm with prilocaine-lidocaine mixture cream and 9.3 mm with lidocaine spray. In the second group, we detected significant difference between mean VAS scores recorded after the administration of lidocaine spray and placebo cream. Mean VAS value was 9.8 mm with lidocaine spray and 24.3 mm with placebo (p<0.05). In the third group, we found statistically significant difference between VAS scores recorded after the administration of prilocaine-lidocaine mixture cream and placebo cream. Mean VAS value was 8.8 mm with prilocaine-lidocaine mixture cream and 33.0 mm with placebo cream (p<0.05). Conclusion: Although both agents administrated before IV cannulation were superior to placebo in adult patients in this study, we can state that these drugs were not superior to each other and showed similar efficacy.en_US
dc.identifier.citationArmağan, E. vd. (2012). "Comparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trial". Hong Kong Journal of Emergency Medicine, 19(3), 183-188.en_US
dc.identifier.endpage188tr_TR
dc.identifier.issn1024-9079
dc.identifier.issue3tr_TR
dc.identifier.scopus2-s2.0-84864072170tr_TR
dc.identifier.startpage183tr_TR
dc.identifier.urihttps://doi.org/10.1177/102490791201900305
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/102490791201900305
dc.identifier.urihttp://hdl.handle.net/11452/24479
dc.identifier.volume19tr_TR
dc.identifier.wos000304644000005tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.relation.journalHong Kong Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEmergency medicineen_US
dc.subjectEfficacyen_US
dc.subjectInfiltration anesthesiaen_US
dc.subjectPeripheral catheterizationen_US
dc.subjectEmla creamen_US
dc.subjectCatheter insertionen_US
dc.subjectBuffered lidocaineen_US
dc.subjectChildrenen_US
dc.subjectVenipunctureen_US
dc.subjectLignocaineen_US
dc.subjectAnalgesiaen_US
dc.subjectChlorideen_US
dc.subjectSuccessen_US
dc.subjectGelen_US
dc.subject.emtreeEmlaen_US
dc.subject.emtreeLidocaineen_US
dc.subject.emtreePlaceboen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAnalgesiaen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCannulaen_US
dc.subject.emtreeCannulationen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHuman experimenten_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeNormal humanen_US
dc.subject.emtreePainen_US
dc.subject.emtreePain assessmenten_US
dc.subject.emtreeProspective studyen_US
dc.subject.emtreeScoring systemen_US
dc.subject.emtreeTopical anesthesiaen_US
dc.subject.emtreeVisual analog scaleen_US
dc.subject.scopusPhlebotomy; Procedural Pain; Lidocaine Plus Prilocaineen_US
dc.subject.wosEmergency medicineen_US
dc.titleComparison of the efficacies of topical anaesthetics in the reduction of the pain during peripheral intravenous cannulation: A randomised trialen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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