Neonatal outcomes of pregnancy complicated by idiopathic thrombocytopenic purpura

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dc.contributor.buuauthorÖzkan, Hilal
dc.contributor.buuauthorÇetinkaya, Merih
dc.contributor.buuauthorKöksal, Nilgün
dc.contributor.buuauthorAli, Rıdvan
dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorÖzkalemkaş, Fahri
dc.contributor.buuauthorÖzkocaman, Vildan
dc.contributor.buuauthorÖzçelik, Tülay
dc.contributor.buuauthorGünay, Ünsal
dc.contributor.buuauthorTunalı, Ahmet
dc.contributor.buuauthorKimya, Yalçın
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.tr_TR
dc.contributor.researcheridAAH-1854-2021tr_TR
dc.contributor.researcheridAAG-8495-2021tr_TR
dc.contributor.scopusid16679325400tr_TR
dc.contributor.scopusid23994946300tr_TR
dc.contributor.scopusid7003323615tr_TR
dc.contributor.scopusid7201813027tr_TR
dc.contributor.scopusid36087235900tr_TR
dc.contributor.scopusid6506622162tr_TR
dc.contributor.scopusid36087855600tr_TR
dc.contributor.scopusid6603145040tr_TR
dc.contributor.scopusid7005424333tr_TR
dc.contributor.scopusid6603885274tr_TR
dc.contributor.scopusid6602797853tr_TR
dc.contributor.scopusid6603919968tr_TR
dc.date.accessioned2022-08-18T12:59:12Z
dc.date.available2022-08-18T12:59:12Z
dc.date.issued2010-01
dc.description.abstractObjective: The aim of this study was to determine the factors associated with the prognosis of newborns born to mothers with idiopathic thrombocytopenic purpura (ITP), and to compare the infants with/without thrombocytopenia in terms of maternal and neonatal characteristics. Study Design: We reviewed the charts of 29 parturients with ITP and their newborns who were born between January 1998 and December 2008. Result: A total of 16 (55%) gravidas had been diagnosed with ITP before pregnancy and 13 (45%) were diagnosed during pregnancy. Thrombocytopenia was observed in 21 gravidas. In total, 17 (58%) gravidas received treatment to increase the platelet count. The majority of deliveries (72.5%) were vaginal. The infant platelet counts at birth ranged from 20 to 336 x 10(9) per liter. None of the neonates had complications attributable to the mode of delivery. Normal platelet counts were determined in 15 newborns, whereas 14 infants had thrombocytopenia at birth. Three (10.3%) neonates had mild, four neonates (13.7%) had moderate and seven neonates (24.1%) had severe thrombocytopenia. The age of the mothers having infants with thrombocytopenia was significantly higher (30 +/- 5.3 vs 25.3 +/- 3.8 years), most of the infants (10/14 (71%)) were males (P<0.05). Conclusion: Pregnancy complicated with ITP generally has a good outcome. Although ITP in pregnancy carries a low risk, careful observation is required for the newborn of gravidas with ITP even when the infant has no bleeding complications at delivery, and infants may require treatment for thrombocytopenia.en_US
dc.identifier.citationÖzkan, H. vd. (2010). "Neonatal outcomes of pregnancy complicated by idiopathic thrombocytopenic purpura". Journal of Perinatology, 30(1), 38-44.en_US
dc.identifier.endpage44tr_TR
dc.identifier.issn0743-8346
dc.identifier.issn1476-5543
dc.identifier.issue1tr_TR
dc.identifier.pubmed19776752tr_TR
dc.identifier.scopus2-s2.0-76849108040tr_TR
dc.identifier.startpage38tr_TR
dc.identifier.urihttps://doi.org/10.1038/jp.2009.134
dc.identifier.urihttps://www.nature.com/articles/jp2009134
dc.identifier.urihttp://hdl.handle.net/11452/28258
dc.identifier.volume30tr_TR
dc.identifier.wos000273441700010tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSpringernatureen_US
dc.relation.journalJournal of Perinatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIdiopathic thrombocytopenic purpuraen_US
dc.subjectITPen_US
dc.subjectPregnancyen_US
dc.subjectNeonatal thrombocytopeniaen_US
dc.subjectNeonatal outcomeen_US
dc.subjectRisken_US
dc.subjectManagementen_US
dc.subjectMothersen_US
dc.subjectWomenen_US
dc.subjectObstetrics & gynecologyen_US
dc.subjectPediatricsen_US
dc.subject.emtreeImmunoglobulinen_US
dc.subject.emtreePrednisoneen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeClinical observationen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeErythrocyte concentrateen_US
dc.subject.emtreeErythrocyte transfusionen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeIdiopathic thrombocytopenic purpuraen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical record reviewen_US
dc.subject.emtreeMultiple cycle treatmenten_US
dc.subject.emtreeNewbornen_US
dc.subject.emtreePregnancyen_US
dc.subject.emtreePregnancy outcomeen_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreeRisk assessmenten_US
dc.subject.emtreeSex differenceen_US
dc.subject.emtreeSplenectomyen_US
dc.subject.emtreeThrombocyte counten_US
dc.subject.emtreeThrombocyte transfusionen_US
dc.subject.emtreeVaginal deliveryen_US
dc.subject.meshAdulten_US
dc.subject.meshFemaleen_US
dc.subject.meshGestational ageen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunoglobulins, intravenousen_US
dc.subject.meshInfant, newbornen_US
dc.subject.meshMaleen_US
dc.subject.meshPlatelet counten_US
dc.subject.meshPregnancyen_US
dc.subject.meshPregnancy complications, hematologicen_US
dc.subject.meshPurpura, thrombocytopenic, idiopathicen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshSex factorsen_US
dc.subject.meshThrombocytopenia, neonatal alloimmuneen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusIdiopathic Thrombocytopenic Purpura; Platelet Count; Thrombocytopeniaen_US
dc.subject.wosObstetrics & gynecologyen_US
dc.subject.wosPediatricsen_US
dc.titleNeonatal outcomes of pregnancy complicated by idiopathic thrombocytopenic purpuraen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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