Irritated seborrhoeic keratosis presenting as a cutaneous horn

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dc.contributor.buuauthorAydoğan, Kenan
dc.contributor.buuauthorÖzbek, Serhat
dc.contributor.buuauthorBalaban Adım, Saduman
dc.contributor.buuauthorTokgöz, Necdet
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Dematoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-0193-1128tr_TR
dc.contributor.researcheridAAH-5441-2021tr_TR
dc.contributor.researcheridAAH-6216-2021tr_TR
dc.contributor.scopusid9739755800tr_TR
dc.contributor.scopusid7005245657tr_TR
dc.contributor.scopusid15730076300tr_TR
dc.contributor.scopusid8286857800tr_TR
dc.date.accessioned2022-01-11T10:44:33Z
dc.date.available2022-01-11T10:44:33Z
dc.date.issued2006-05
dc.description.abstractSeborrheic keratosis (SK) is a common benign cutaneous tumour that is frequently seen on the trunk, extremities, head and neck of geriatric population, and presents with a variety of clinical and histopathologic appearance.1 Malignant transformation of SK, although rare, appears to occur more particularly in irritated lesions of the elderly located on the head, neck and flexures.1 Premalignant skin lesions and malignant tumours reported to arise in SKs are basal cell carcinoma, Bowen's disease, keratoacanthoma, squamous cell carcinoma (SCC), adenocarcinoma, melanoma, eccrine porocarcinoma and ganglioneuroma.2-5 We describe herein a case with an irritated SK presenting as a cutaneous horn arising on her face. A 65-year-old woman presented with lesion on her left temporal area of 4 years’ duration. The mass had noticeably increased in size over several months and was accompanied by horn formation. Upon examination a dome-like yellow to black, polipoid greasy surfaced elevation with a horn formation of 2 × 5 cm in diamater was seen on the area (fig. 1). The histological appearances were consistent with irritated SK on excisional biopsy. As this lesion partly mimics SCC both clinically and histopathologically, we performed an immunohistochemical analysis of p53 and Ki-67 to see its growth potential. The percentage of p53 positive cells was > 50% in the specimen. Ki-67 reactivity was noted in the nucleus of basal or suprabasal region and the percentage of Ki-67 positive cells was 2.4%.en_US
dc.identifier.citationAydoğan, K. vd. (2006). ''Irritated seborrhoeic keratosis presenting as a cutaneous horn''. Journal of the European Academy of Dermatology and Venereology, 20(5), 626-628.en_US
dc.identifier.endpage628tr_TR
dc.identifier.issn0926-9959
dc.identifier.issue5tr_TR
dc.identifier.pubmed16684308tr_TR
dc.identifier.scopus2-s2.0-33646027871tr_TR
dc.identifier.startpage626tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1468-3083.2006.01521.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1468-3083.2006.01521.x
dc.identifier.urihttp://hdl.handle.net/11452/24004
dc.identifier.volume20tr_TR
dc.identifier.wos000237063100035tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalJournal of the European Academy of Dermatology and Venereologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDermatologyen_US
dc.subjectNeoplasmsen_US
dc.subjectSeborrheicen_US
dc.subjectKeratosisen_US
dc.subjectHumansen_US
dc.subjectFemaleen_US
dc.subjectFacial dermatosesen_US
dc.subjectDiagnosis, differentialen_US
dc.subjectAgeden_US
dc.subject.emtreeKi 67 antigenen_US
dc.subject.emtreeSquamous cellen_US
dc.subject.emtreeSkin irritationen_US
dc.subject.emtreeSkin inflammationen_US
dc.subject.emtreeSkin biopsyen_US
dc.subject.emtreeSeborrheic keratosisen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeLetteren_US
dc.subject.emtreeKeratinocyteen_US
dc.subject.emtreeImmunohistochemistryen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeDisease durationen_US
dc.subject.emtreeCell proliferationen_US
dc.subject.emtreeCell differentiationen_US
dc.subject.emtreeCell counten_US
dc.subject.emtreeCase reporten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAcantholysisen_US
dc.subject.meshKeratosis, seborrheicen_US
dc.subject.meshHumansen_US
dc.subject.meshFemaleen_US
dc.subject.meshFacial dermatosesen_US
dc.subject.meshDiagnosis, differentialen_US
dc.subject.meshAgeden_US
dc.subject.scopusSeborrheic Keratosis; Dermatosis Papulosa Nigra; Keratoderma Blennorrhagicaen_US
dc.subject.wosDermatologyen_US
dc.titleIrritated seborrhoeic keratosis presenting as a cutaneous hornen_US
dc.typeLetter
dc.wos.quartileQ2en_US

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