Determination of phenolic compounds in Prunella L. by liquid chromatography-diode array detection

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dc.contributor.buuauthorŞahin, Saliha
dc.contributor.buuauthorDemir, Cevdet
dc.contributor.buuauthorMalyer, Hulusi M.
dc.contributor.departmentUludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-1508-0181tr_TR
dc.contributor.orcid0000-0002-9381-0410tr_TR
dc.contributor.researcheridAAH-2892-2021tr_TR
dc.contributor.researcheridABA-2005-2020tr_TR
dc.contributor.scopusid15027401600tr_TR
dc.contributor.scopusid7003565902tr_TR
dc.contributor.scopusid6602736554tr_TR
dc.date.accessioned2021-12-13T12:19:45Z
dc.date.available2021-12-13T12:19:45Z
dc.date.issued2011-07-15
dc.description.abstractFour species of Prunella L. (Prunella vulgaris L., Prunella laciniata L., Prunella grand:flora L. and Prunella orientalis Bornm.) belong to the family of Lamiaceae and representing popular Western and Chinese herbal medicine were examined for the content of phenolic compounds. Phenolic acids (rosmarinic acid, caffeic acid, ferulic acid, chlorogenic acid, protocatechuic acid), flavonoids (rutin, quercetin) in different quantitative proportions depending on extracts were determined by the rapid, selective and accurate method combining solvent/acid hydrolysis extraction and high performance liquid chromatographydiode array detection (HPLC-DAD). Water, methanol, butanol, acetonitrile, ethyl acetate, hexane and their acidic solutions were used to examine the efficiency of different solvent systems for the extraction of phenolic compounds. Acid hydrolysis extraction was established as the most suitable extraction method for phenolic compounds.en_US
dc.identifier.citationŞahin, S. vd. (2011). "Determination of phenolic compounds in Prunella L. by liquid chromatography-diode array detection". Journal of Pharmaceutical and Biomedical Analysis, 55(5), 1227-1230.en_US
dc.identifier.endpage1230tr_TR
dc.identifier.issn0731-7085
dc.identifier.issn1873-264X
dc.identifier.issue5tr_TR
dc.identifier.pubmed21498022tr_TR
dc.identifier.scopus2-s2.0-79956123222tr_TR
dc.identifier.startpage1227tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2011.03.016
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0731708511001506
dc.identifier.urihttp://hdl.handle.net/11452/23212
dc.identifier.volume55tr_TR
dc.identifier.wos000291129700050tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.bap2009/38tr_TR
dc.relation.journalJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChemistryen_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectPrunella L.en_US
dc.subjectPhenolic compoundsen_US
dc.subjectHPLC-DADen_US
dc.subjectSolvent extractionen_US
dc.subjectHydrolysisen_US
dc.subjectPlant extracten_US
dc.subjectFlavonoidsen_US
dc.subjectHPLCen_US
dc.subject.emtreeAcetic acid ethyl esteren_US
dc.subject.emtreeAcetonitrileen_US
dc.subject.emtreeButanolen_US
dc.subject.emtreeCaffeic aciden_US
dc.subject.emtreeChlorogenic aciden_US
dc.subject.emtreeFerulic aciden_US
dc.subject.emtreeHexaneen_US
dc.subject.emtreeMethanolen_US
dc.subject.emtreeProtocatechuic aciden_US
dc.subject.emtreePhenol derivativeen_US
dc.subject.emtreePrunella vulgaris extracten_US
dc.subject.emtreeQuercetinen_US
dc.subject.emtreeRosmarinic aciden_US
dc.subject.emtreeRutosideen_US
dc.subject.emtreeSolventen_US
dc.subject.emtreeWateren_US
dc.subject.emtreeAccuracyen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeDiodeen_US
dc.subject.emtreeDrug determinationen_US
dc.subject.emtreeExaminationen_US
dc.subject.emtreeHerbal medicineen_US
dc.subject.emtreeHigh performance liquid chromatographen_US
dc.subject.emtreeHydrolysisen_US
dc.subject.emtreeLiquid chromatographyen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreePrunellaen_US
dc.subject.emtreePrunella grandifloraen_US
dc.subject.emtreePrunella laciniataen_US
dc.subject.emtreePrunella orientalien_US
dc.subject.emtreeQuantitative analysisen_US
dc.subject.emtreeSolution and solubilityen_US
dc.subject.meshChemistry techniques, analyticalen_US
dc.subject.meshChemistry, pharmaceuticalen_US
dc.subject.meshChromatography, high pressure liquiden_US
dc.subject.meshChromatography, liquiden_US
dc.subject.meshHydrolysisen_US
dc.subject.meshPhenolen_US
dc.subject.meshPlant extractsen_US
dc.subject.meshPrunellaen_US
dc.subject.meshSolventsen_US
dc.subject.meshWateren_US
dc.subject.scopusPrunella; Machaeranthera; Derrisen_US
dc.subject.wosChemistry, analyticalen_US
dc.subject.wosPharmacology & pharmacyen_US
dc.titleDetermination of phenolic compounds in Prunella L. by liquid chromatography-diode array detectionen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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