LC method for the analysis of acetylsalicylic acid, caffeine and codeine phosphate in pharmaceutical preparations

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dc.contributor.authorAltun, Mehmet Levent
dc.contributor.authorCeyhan, Timurhan
dc.contributor.authorKartal, Müjgan
dc.contributor.authorAtay, Tuğba
dc.contributor.authorÖzdemir, N.
dc.contributor.buuauthorCevheroğlu, Şemsettin
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi.tr_TR
dc.contributor.scopusid6602507499en_US
dc.date.accessioned2021-08-23T08:44:33Z
dc.date.available2021-08-23T08:44:33Z
dc.date.issued2001-04
dc.description.abstractAn accurate, simple, reproducible and sensitive method for the determination of acetylsalicylic acid, caffeine and codeine phosphate has been developed and validated. Acetylsalicylic acid, caffeine and codeine phosphate were separated using a mu Bofidapack C-8 column by isocratic elution with flow rate 1.0 ml/min. The mobile phase composition was 125/125/250/0.5 (v/v) isopropyl alcohol, acetonitrile. water and omicron -phosphoric acid. The samples were detected at 215 nm using photo-diode array detector. The linear range of detection for acetylsalicylic acid, caffeine and codeine phosphate were between 0.40 and 1000, 0.25 and 250, and 0.48 and 96 mug/ml, respectively. The linearity, range, selectivity, system performance parameters, precision, accuracy, and ruggedness for acetylsalicylic acid, caffeine and codeine phosphate were also shown to have acceptable values.en_US
dc.identifier.citationAltun, M. L. vd. (2001). "LC method for the analysis of acetylsalicylic acid, caffeine and codeine phosphate in pharmaceutical preparations". Journal of Pharmaceutical and Biomedical Analysis, 25(1), 93-101.en_US
dc.identifier.endpage101tr_TR
dc.identifier.issn0731-7085
dc.identifier.issue1tr_TR
dc.identifier.pubmed11274862tr_TR
dc.identifier.scopus2-s2.0-0035076243tr_TR
dc.identifier.startpage93tr_TR
dc.identifier.urihttps://doi.org/10.1016/S0731-7085(00)00488-X
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S073170850000488
dc.identifier.urihttp://hdl.handle.net/11452/21519
dc.identifier.volume25tr_TR
dc.identifier.wos000168112900012
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.collaborationSanayitr_TR
dc.relation.collaborationYurt içitr_TR
dc.relation.journalJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcetylsalicylic aciden_US
dc.subjectCaffeineen_US
dc.subjectCodeine phosphate high-performance liquid chromatographyen_US
dc.subjectValidationen_US
dc.subjectPerformance liquid-chromatographyen_US
dc.subjectAscorbic-aciden_US
dc.subjectTabletsen_US
dc.subjectAspirinen_US
dc.subjectSpectrophotometryen_US
dc.subject.scopusParacetamol; 4-Aminophenol; Glassy Carbon Electrodeen_US
dc.subject.wosChemistry, analyticalen_US
dc.subject.wosPharmacology & pharmacyen_US
dc.titleLC method for the analysis of acetylsalicylic acid, caffeine and codeine phosphate in pharmaceutical preparationsen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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