Ocular surface changes with applanation contact lens and coupling fluid use after argon laser photocoagulation in noninsulin-dependent diabetes mellitus

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dc.contributor.authorAvcı, Remzi
dc.contributor.authorGoto, Eiki
dc.contributor.authorShimmura, Shigeto
dc.contributor.authorShimazaki, Jun
dc.contributor.authorTsubota, Kazuo
dc.contributor.buuauthorDoğru, Murat
dc.contributor.buuauthorKaderli, Berkant
dc.contributor.buuauthorGelişken, Öner
dc.contributor.buuauthorYücel, Ali
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid7006540932tr_TR
dc.contributor.scopusid6507602756en_US
dc.contributor.scopusid6602526353tr_TR
dc.contributor.scopusid57225839918tr_TR
dc.date.accessioned2022-03-30T12:07:58Z
dc.date.available2022-03-30T12:07:58Z
dc.date.issued2004-09
dc.description.abstractPURPOSE: To describe the effect of coupling solutions used during laser photocoagulation on the ocular surface of patients with non insulin-dependent diabetes mellitus (NIDDM). DESIGN: A prospective case-controlled study. METHODS: Ninety,two eyes of 46 NIDDM patients with clinically significant macular edema, poor metabolic control of diabetes, and peripheral neuropathy and 100 eyes of 50 normal control subjects were studied. The patients' eyes were assigned to argon green focal/grid laser photocoagulation using an applanation contact lens and one of the coupling fluids; 2% methocel, Thilo-Tears Gel, 1.4% sodium hyaluronate, or 0.9% simple saline. The control subjects received time-matched three-mirror contact lens fundus examinations. All subjects under, went corneal sensitivity measurements, Schirmer test, tear film breakup time, and corneal fluorescein staining before as well as 3 and 8 days after the laser procedures and contact lens examinations. Patients with corneal problems persisting after 8 days were followed longer. RESULTS: Diabetic eyes assigned to 2% methocel and 1.4% sodium hyaluronate had significantly lower mean corneal sensitivities and break-up time values as well as significantly higher mean fluorescein staining scores at all examination points after laser photocoagulation. All diabetic eyes with aqueous deficiency assigned to 2% methocel and 1.4% sodium hyaluronate developed delayed corneal epithelial healing. CONCLUSION: The use of viscous coupling solutions during applanation contact lens-aided laser procedures may be detrimental for the corneal epithelium in poorly controlled NIDDM patients with peripheral neuropathy and coexisting aqueous deficiency.en_US
dc.identifier.citationDoğru, M. vd. (2004). “Ocular surface changes with applanation contact lens and coupling fluid use after argon laser photocoagulation in noninsulin-dependent diabetes mellitus”. American Journal of Ophthalmology, 138(3), 381-388.en_US
dc.identifier.endpage388tr_TR
dc.identifier.issn0002-9394
dc.identifier.issue3tr_TR
dc.identifier.pubmed15364219tr_TR
dc.identifier.scopus2-s2.0-4444248169tr_TR
dc.identifier.startpage381tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.ajo.2004.04.008
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0002939404003897
dc.identifier.urihttp://hdl.handle.net/11452/25455
dc.identifier.volume138tr_TR
dc.identifier.wos000224065700008tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationYurt dışıtr_TR
dc.relation.journalAmerican Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOphthalmologyen_US
dc.subjectEpithelial barrier functionen_US
dc.subjectCorneal sensitivityen_US
dc.subjectVitrectomyen_US
dc.subjectRatsen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArgon plasma coagulationen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeContact lensen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCornea epitheliumen_US
dc.subject.emtreeCornea sensibilityen_US
dc.subject.emtreeEye diseaseen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeHealingen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMetabolic regulationen_US
dc.subject.emtreeNon insulin dependent diabetes mellitusen_US
dc.subject.emtreeOphthalmoscopyen_US
dc.subject.emtreePeripheral neuropathyen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProspective studyen_US
dc.subject.emtreeRetina macula edemaen_US
dc.subject.emtreeSchirmer testen_US
dc.subject.emtreeTear filmen_US
dc.subject.emtreeFluoresceinen_US
dc.subject.emtreeHyaluronic aciden_US
dc.subject.emtreeMethylcelluloseen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCase-control studiesen_US
dc.subject.meshContact lensesen_US
dc.subject.meshCorneal diseasesen_US
dc.subject.meshDiabetes mellitus, type 2en_US
dc.subject.meshDiabetic retinopathyen_US
dc.subject.meshEpithelium, cornealen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluoresceinen_US
dc.subject.meshFluorophotometryen_US
dc.subject.meshHumansen_US
dc.subject.meshHyaluronic aciden_US
dc.subject.meshLaser coagulationen_US
dc.subject.meshMacular edema, cystoiden_US
dc.subject.meshMaleen_US
dc.subject.meshMethylcelluloseen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshOphthalmic solutionsen_US
dc.subject.meshProspective studiesen_US
dc.subject.meshTearsen_US
dc.subject.meshWound healingen_US
dc.subject.scopusPhacoemulsification; Capillary Endothelial Cell; Eye Banksen_US
dc.subject.wosOphthalmologyen_US
dc.titleOcular surface changes with applanation contact lens and coupling fluid use after argon laser photocoagulation in noninsulin-dependent diabetes mellitusen_US
dc.typeArticle
dc.wos.quartileQ1en_US

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