Arterial lesions in Behcet's disease

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dc.contributor.buuauthorSaba, Davit
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.buuauthorBayram, Ahmet Sami
dc.contributor.buuauthorErdoğan, Cüneyt
dc.contributor.buuauthorDilek, Kamil
dc.contributor.buuauthorGebitekin, Cengiz
dc.contributor.buuauthorÖzkan, Hayati
dc.contributor.buuauthorÖzer, Z. Gökalp
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Romatoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kalp Damar Cerrahisi Anabilim Dalı.tr_TR
dc.contributor.researcheridABB-7580-2020tr_TR
dc.contributor.scopusid55987378200tr_TR
dc.contributor.scopusid6603722836tr_TR
dc.contributor.scopusid8347194000tr_TR
dc.contributor.scopusid8293835700tr_TR
dc.contributor.scopusid56005080200tr_TR
dc.contributor.scopusid6602156436tr_TR
dc.contributor.scopusid7103355993tr_TR
dc.contributor.scopusid6701509634tr_TR
dc.date.accessioned2021-09-08T08:53:15Z
dc.date.available2021-09-08T08:53:15Z
dc.date.issued2003-05
dc.description.abstractBackground: Arterial involvement is a rare but serious condition in the course of Behcet's disease. We aimed to assess the results of therapeutic approaches in our patients with arterial lesions caused by Behcet's disease. Patients and methods: The records of 534 patients with Behcet's disease between 1987 and 2002 were retrospectively evaluated for the presence of arterial lesions. All patients were followed up regularly, at 3 to 6 months intervals. Results: Arterial lesions were diagnosed in 21 (3.9%) patients. Eight of these patients had pulmonary artery aneurysms (PAA), and the other 13 patients had non-pulmonary arterial lesions. Urgent surgical intervention was performed in three patients with PAA leading to death in all three. In addition, three other patients died due to massive haemoptysis at home despite to immunosuppressive therapy. Only two out of eight patients with PAA are still alive who were treated with cyclophophamide and corticosteroids. Thirteen operations were performed in 7 out of 13 patients having non-puhnonary arterial lesions. Although ten of the operations were primary operations, three reoperations had to be performed. A stent-graft was applied for the management of an iliac artery aneurysm in one patient. Only one patient died 8 years after the first non-pulmonary arterial involvement following a type IV thoracoabdominal aortic aneurysm repair Five patients with arterial occlusive lesions were successfully treated by corticosteroids. Conclusions: Pulmonary artery aneurysms in Behcet's disease patients have a poor prognosis despite any form of therapy. High dose corticosteroids alone can be successfully used for isolated non-pulmonary arterial occlusive lesions, unless disabling symptoms occur. Surgery or stent-graft insertion is indicated,for non-pulmonary arterial aneurysms because these aneurysms entail high risk of complications.en_US
dc.identifier.citationSaba, D. vd. (2003). “Arterial lesions in Behcet's disease”. Vasa-Journal of Vascular Diseases, 32(2), 75-81.en_US
dc.identifier.endpage81tr_TR
dc.identifier.issn0301-1526
dc.identifier.issue2tr_TR
dc.identifier.pubmed12945099tr_TR
dc.identifier.scopus2-s2.0-0037524304tr_TR
dc.identifier.startpage75tr_TR
dc.identifier.urihttps://doi.org/10.1024/0301-1526.32.2.75
dc.identifier.urihttps://econtent.hogrefe.com/doi/10.1024/0301-1526.32.2.75
dc.identifier.urihttp://hdl.handle.net/11452/21765
dc.identifier.volume32tr_TR
dc.identifier.wos000183487300004tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherVerlag Hans Huberen_US
dc.relation.journalVasa - Journal of Vascular Diseasesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCardiovascular system & cardiologyen_US
dc.subjectBehcet's diseaseen_US
dc.subjectArterial lesionsen_US
dc.subjectPulmonary artery aneurysmen_US
dc.subjectVascular involvementen_US
dc.subjectPulmonary manifestationsen_US
dc.subjectAneurysmsen_US
dc.subjectManagementen_US
dc.subjectDiagnosisen_US
dc.subject.emtreeAzathioprineen_US
dc.subject.emtreeCorticosteroiden_US
dc.subject.emtreeCyclophosphamideen_US
dc.subject.emtreeImmunosuppressive agenten_US
dc.subject.emtreePrednisoloneen_US
dc.subject.emtreeAbdominal aorta aneurysmen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArtery diseaseen_US
dc.subject.emtreeArtery occlusionen_US
dc.subject.emtreeBehcet diseaseen_US
dc.subject.emtreeBlood vessel graften_US
dc.subject.emtreeCause of deathen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCorticosteroid therapyen_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeHemoptysisen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeImmunosuppressive treatmenten_US
dc.subject.emtreeLobectomyen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreePulmonary artery aneurysmen_US
dc.subject.emtreeReoperationen_US
dc.subject.emtreeStenten_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.scopusBehcet syndrome; False aneurysm; Systemic vasculitisen_US
dc.subject.wosPeripheral vascular diseaseen_US
dc.titleArterial lesions in Behcet's diseaseen_US
dc.typeArticle

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