Comparison of SPECT findings and neuropsychological sequelae in carbon monoxide and organophosphate poisoning
dc.contributor.buuauthor | Özyurt, Gürayten | |
dc.contributor.buuauthor | Kaya, Fatma Nur | |
dc.contributor.buuauthor | Kahveci, Sohret Ferda | |
dc.contributor.buuauthor | Alper, Eray | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0003-4820-2288 | tr_TR |
dc.contributor.researcherid | AAG-9356-2021 | tr_TR |
dc.contributor.researcherid | AAI-8213-2021 | tr_TR |
dc.contributor.scopusid | 6603035486 | tr_TR |
dc.contributor.scopusid | 7003619647 | tr_TR |
dc.contributor.scopusid | 6602405968 | tr_TR |
dc.contributor.scopusid | 7006827670 | tr_TR |
dc.date.accessioned | 2024-03-21T06:00:50Z | |
dc.date.available | 2024-03-21T06:00:50Z | |
dc.date.issued | 2008 | |
dc.description.abstract | Abnormal regional cerebral blood flow in patients with acute carbon monoxide (CO) and organophosphate (OP) poisoning was examined using (99m) Tc-hexamethylpropylene amine oxime (HMPAO) brain single photon emission computed tomography (SPECT) in fourteen patients. We evaluated the predictive significance of acute phase brain SPECT findings for long-term neuropsychological sequelae. Changes were found in the frontal, temporal, parietal lobes within the first week after both types of poisoning. The distribution of the hypoperfused cerebral areas as demonstrated by (99m) Tc-HMPAO imaging was similar in the two groups during the acute phase. Neuropsychological sequelae developed in five patients poisoned with OP and six with CO. Patients who had SPECT findings heterogeneously or in the temporal or frontal lobes displayed disorientation. Those with fronto-parietal and frontal lobe changes displayed mental confusion. Parkinsonism also was observed in patients with parieto-occipital, parietal and frontal lobe lesions. The distribution of these lesions appears to predict the long term sequelae of these poisonings, though additional studies with larger numbers of patients are needed to confirm the role of SPECT imaging in both OP and CO poisonings. | en_US |
dc.identifier.citation | Özyurt, G. vd. (2008). "Comparison of SPECT findings and neuropsychological sequelae in carbon monoxide and organophosphate poisoning". Clinical Toxicology, 46(3), 218-221. | en_US |
dc.identifier.doi | https://doi.org/10.1080/15563650701378704 | en_US |
dc.identifier.endpage | 221 | tr_TR |
dc.identifier.issn | 1556-3650 | |
dc.identifier.issue | 3 | tr_TR |
dc.identifier.pubmed | 18344103 | tr_TR |
dc.identifier.scopus | 2-s2.0-40849094313 | tr_TR |
dc.identifier.startpage | 218 | tr_TR |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1080/15563650701378704 | en_US |
dc.identifier.uri | https://hdl.handle.net/11452/40537 | en_US |
dc.identifier.volume | 46 | tr_TR |
dc.identifier.wos | 000254043000007 | tr_TR |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Taylor | en_US |
dc.relation.journal | Clinical Toxicology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Carbon monoxide poisoning | en_US |
dc.subject | Neuropsychological sequelae | en_US |
dc.subject | Organophosphate poisoning | en_US |
dc.subject | SPECT | en_US |
dc.subject | Emission computed-tomography | en_US |
dc.subject | Hmpao brain spect | en_US |
dc.subject | Nitric-oxide | en_US |
dc.subject | Intoxication | en_US |
dc.subject | Encephalopathy | en_US |
dc.subject | Neuropathology | en_US |
dc.subject | Features | en_US |
dc.subject | Mri | en_US |
dc.subject | Toxicology | en_US |
dc.subject.emtree | Carbon monoxide | en_US |
dc.subject.emtree | Hexamethylpropylene amine oxime technetium tc 99m | en_US |
dc.subject.emtree | Organophosphate | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Brain blood flow | en_US |
dc.subject.emtree | Brain perfusion | en_US |
dc.subject.emtree | Carbon monoxide intoxication | en_US |
dc.subject.emtree | Clinical article | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Disorientation | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Frontal cortex | en_US |
dc.subject.emtree | Frontal lobe | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Mental disease | en_US |
dc.subject.emtree | Neurotoxicity | en_US |
dc.subject.emtree | Occipital cortex | en_US |
dc.subject.emtree | Parietal lobe | en_US |
dc.subject.emtree | Parkinsonism | en_US |
dc.subject.emtree | Single photon emission computer tomography | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Brain | en_US |
dc.subject.mesh | Carbon monoxide poisoning | en_US |
dc.subject.mesh | Carboxyhemoglobin | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Neuropsychological tests | en_US |
dc.subject.mesh | Phosphorica acid esters | en_US |
dc.subject.mesh | Poisoning | en_US |
dc.subject.mesh | Radiopharmaceuticals | en_US |
dc.subject.mesh | Technetium tc 99m exametazime | en_US |
dc.subject.mesh | Tomography, emission-computed, single-photon | en_US |
dc.subject.scopus | Carbon Monoxide Intoxication; Acute; Hyperbaric Oxygen Therapy | en_US |
dc.subject.wos | Toxicology | en_US |
dc.title | Comparison of SPECT findings and neuropsychological sequelae in carbon monoxide and organophosphate poisoning | en_US |
dc.type | Article | en_US |
dc.wos.quartile | Q3 (Toxicology) | en_US |
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