Gliadin-specific IgA antibodies in breast milk

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dc.contributor.buuauthorÖzkan, Tanju
dc.contributor.buuauthorÖzeke, Turgut
dc.contributor.buuauthorMeral, Adalet Güneş
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Çocuk Gastroenteroloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.tr_TR
dc.date.accessioned2021-09-09T10:52:48Z
dc.date.available2021-09-09T10:52:48Z
dc.date.issued2000
dc.description.abstractBreast-feeding helps to protect against coeliac disease because of the presence of antigliadin-IgA antibodies(AGA-IgA) in breast milk. The aim of this study was to assess the concentrations of AGA-IgA in breast milk during lactation, and whether these concentrations vary with the socioeconomic status of the women. Samples of serum for determination of IgA albumin and AGA-IgR, and samples of breast-milk for AGA-IgA were collected from 105 healthy mothers (aged 17 - 36 years). Women were divided into two groups: group 1 were of low and group 2 were of high socioeconomic status. No differences were observed between the study parameters in the two groups. Serum AGA-IgA in both groups was, however, significantly lower than that in colostrum. AGA-IgA concentrations in both groups gradually decreased during 45 days of lactation; the difference between colostrum and the samples taken at days 10 and 30 - 45 of lactation was significant. The encouragement of sufficient and long-term (e.g. 4 - 6 months) breast-feeding seems likely to be beneficial in preventing coeliac disease.en_US
dc.identifier.citationÖzkan, T. vd. (2000). "Gliadin-specific IgA antibodies in breast milk". Journal of International Medical Research, 28(5), 234-240.en_US
dc.identifier.endpage240tr_TR
dc.identifier.issn0300-0605
dc.identifier.issue5tr_TR
dc.identifier.pubmed11092234tr_TR
dc.identifier.scopus2-s2.0-0033760160tr_TR
dc.identifier.startpage234tr_TR
dc.identifier.urihttps://doi.org/10.1177/147323000002800506
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/147323000002800506
dc.identifier.urihttp://hdl.handle.net/11452/21806
dc.identifier.volume28tr_TR
dc.identifier.wos000165091500006tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.relation.journalJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectResearch & experimental medicineen_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectCoeliac diseaseen_US
dc.subjectAntigliadin antibodiesen_US
dc.subjectBreast-feedingen_US
dc.subjectBreast milken_US
dc.subjectCeliac-diseaseen_US
dc.subjectAntigensen_US
dc.subjectPassageen_US
dc.subjectSalivaen_US
dc.subjectSerumen_US
dc.subject.scopusHuman Milk; Colostrum; Lactation Stageen_US
dc.subject.wosMedicine, research & experimentalen_US
dc.subject.wosPharmacology & pharmacyen_US
dc.titleGliadin-specific IgA antibodies in breast milken_US
dc.typeArticle
dc.wos.quartileQ4en_US

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