Comparison of topical and subconjunctival anesthesia in intravitreal injection administrations

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dc.contributor.buuauthorKaderli, Berkant
dc.contributor.buuauthorAvcı, Remzi
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı.tr_TR
dc.date.accessioned2021-09-10T11:31:49Z
dc.date.available2021-09-10T11:31:49Z
dc.date.issued2006
dc.description.abstractPURPOSE. To compare the effectiveness of topical and subconjunctival anesthesia in intravitreal injection administrations. METHODS. Twenty-eight patients from a university clinic with bilateral diabetic macular edema were prospectively randomized to receive intravitreal injection of 4 mg triamcinolone under topical anesthesia for one eye and subconjunctival anesthesia for the other eye by using lidocaine 4%. Patients were asked to grade the pain they experienced during administration of both anesthesia and intravitreal injection by using a 4-point pain scale: from 0=no pain to 3=severe pain. Complications that developed during both procedures were recorded. RESULTS. The mean pain score experienced during subconjunctival injections was 0. 78 0. 62, whereas no anesthesia-related pain was reported in the topical group. The mean pain score experienced during intravitreal injection was 1.64 +/- 0.67 in the topical and 0.85 +/- 0.52 in the subconjunctival group (p < 0.001). The mean total pain scores of both procedures were 0.82 +/- 0.34 in the topical and 0.82 +/- 0.51 in the subconjunctival group (p > 0.05). Nine eyes (32%) developed subconjunctival haemorrhage after subconjunctival injection, whereas no anesthesia-related complication developed in the topical group. Subconjunctival haemorrhage was also observed in 5 eyes (18%) in the topical group and in 11 eyes (40%) in the subconjunctival group (p > 0.05) after intravitreal injection. CONCLUSIONS. Although subconjunctival anesthesia provides better pain control during intravitreal injections, its application is more painful and leads to subconjunctival haemorrhage. Moreover, the mean total pain scores are similar in both methods. Therefore, topical anesthesia may be more suitable for daily practice.en_US
dc.identifier.citationKaderli, B. ve Avcı, R. (2006). ''Comparison of topical and subconjunctival anesthesia in intravitreal injection administrations''. European Journal of Ophthalmology, 16(5), 718-721.en_US
dc.identifier.endpage721tr_TR
dc.identifier.issn1120-6721
dc.identifier.issue5tr_TR
dc.identifier.pubmed17061223tr_TR
dc.identifier.scopus2-s2.0-33845299506tr_TR
dc.identifier.startpage718tr_TR
dc.identifier.urihttps://doi.org/10.1177/112067210601600509
dc.identifier.urihttps://journals.sagepub.com/doi/10.1177/112067210601600509
dc.identifier.urihttp://hdl.handle.net/11452/21859
dc.identifier.volume16tr_TR
dc.identifier.wos000242895900010tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSage Publicationsen_US
dc.relation.journalEuropean Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOphthalmologyen_US
dc.subjectTopical anesthesiaen_US
dc.subjectSubconjunctival anesthesiaen_US
dc.subjectIntravitreal injectionen_US
dc.subjectGelen_US
dc.subjectGasen_US
dc.subjectTrialen_US
dc.subjectTherapyen_US
dc.subjectDegenerationen_US
dc.subjectCataract-surgeryen_US
dc.subjectSubmacular hemorrhageen_US
dc.subjectTriamcinolone acetonideen_US
dc.subjectDiabetic macular edemaen_US
dc.subjectTissue-plasminogen activatoren_US
dc.subject.scopusIntravitreal Drug Administration; Endophthalmitis; Ranibizumaben_US
dc.subject.wosOphthalmologyen_US
dc.titleComparison of topical and subconjunctival anesthesia in intravitreal injection administrationsen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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