Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea

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dc.contributor.buuauthorEryılmaz, Salih
dc.contributor.buuauthorAydınlar, Ali
dc.contributor.buuauthorŞentürk, Tunay
dc.contributor.buuauthorUrsavaş, Ahmet
dc.contributor.buuauthorAydın, Aysel Kaderli
dc.contributor.buuauthorÖzdemir, Bülent
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalıtr_TR
dc.contributor.orcid0000-0002-8974-8837tr_TR
dc.contributor.researcheridAAI-3169-2021tr_TR
dc.contributor.researcheridAAI-6632-2021tr_TR
dc.contributor.researcheridC-1517-2017tr_TR
dc.contributor.scopusid37037269800tr_TR
dc.contributor.scopusid6603131517tr_TR
dc.contributor.scopusid8342098300tr_TR
dc.contributor.scopusid8329319900tr_TR
dc.contributor.scopusid36460564300tr_TR
dc.contributor.scopusid7004168959tr_TR
dc.date.accessioned2022-07-04T10:11:01Z
dc.date.available2022-07-04T10:11:01Z
dc.date.issued2010-10
dc.description.abstractBackground: Reduced arterial elasticity is an important mediator of accelerated atherogenesis and consequent increased cardiovascular morbidity in obstructive sleep apnea (OSA). The aim of our study was to investigate whether continuous positive airway pressure (CPAP) therapy may improve arterial elasticity in subjects with OSA. Methods: In 44 subjects with OSA, we measured arterial elasticity by applanation tonometry before and after 6 months of treatment with CPAP. Nine OSA+ subjects withdrew from the study. Results: The 35 patients with OSA who completed the 6-month CPAP treatment showed a marked reduction in both the large artery (LAEI, P = 0.001) and small artery (SAEI, P = 0.009) elasticity indices, independent of potential confounders. In OSA+ subjects who withdrew from the study, SAEI and LAEI did not change significantly over time. Conclusions: Six months of CPAP therapy improves arterial elasticity in subjects with OSA.en_US
dc.identifier.citationEryılmaz, S. vd. (2010). "Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea". Respiratory Medicine, 104(10), 1571-1576.en_US
dc.identifier.endpage1576tr_TR
dc.identifier.issn0954-6111
dc.identifier.issn1532-3064
dc.identifier.issue10tr_TR
dc.identifier.pubmed20570124tr_TR
dc.identifier.scopus2-s2.0-77956340887tr_TR
dc.identifier.startpage1571tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2010.05.002
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0954611110002167
dc.identifier.urihttp://hdl.handle.net/11452/27648
dc.identifier.volume104tr_TR
dc.identifier.wos000282247300024tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherW B Saunders COen_US
dc.relation.journalRespiratory Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObstructive sleep apnea syndromeen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectArterial elasticityen_US
dc.subjectContinuous positive airway pressureen_US
dc.subjectPulse-wave velocityen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectNitric-oxideen_US
dc.subjectStiffnessen_US
dc.subjectAtherosclerosisen_US
dc.subjectAssociationen_US
dc.subjectModerateen_US
dc.subjectCPAPen_US
dc.subjectCardiovascular system & cardiologyen_US
dc.subjectRespiratory systemen_US
dc.subject.emtreeArtery elasticityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCardiovascular risken_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeElasticityen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreePositive end expiratory pressureen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeSleep apnea syndromeen_US
dc.subject.emtreeTherapy effecten_US
dc.subject.meshArteriesen_US
dc.subject.meshContinuous positive airway pressureen_US
dc.subject.meshElasticityen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPolysomnographyen_US
dc.subject.meshSleep apnea, obstructiveen_US
dc.subject.meshTime factorsen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.scopusObstructive Sleep Apnea; Positive End Expiratory Pressure; Pressure Treatmenten_US
dc.subject.wosCardiac & cardiovascular systemsen_US
dc.subject.wosRespiratory systemen_US
dc.titleContinuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apneaen_US
dc.typeArticle
dc.wos.quartileQ2en_US

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