Comparison of lipid emulsions on antioxidant capacity in preterm infants receiving parenteral nutrition

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dc.contributor.buuauthorKöksal, Nilgün
dc.contributor.buuauthorKavurt, Ahmet Vedat
dc.contributor.buuauthorÇetinkaya, Merih
dc.contributor.buuauthorİlçöl, Yeşim Özarda
dc.contributor.buuauthorÖzkan, Hilal
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatri Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Neontoloji Anabilim Dalı.tr_TR
dc.contributor.researcheridAAG-8393-2021tr_TR
dc.contributor.researcheridAAL-8873-2021tr_TR
dc.contributor.scopusid7003323615tr_TR
dc.contributor.scopusid48361292600tr_TR
dc.contributor.scopusid23994946300tr_TR
dc.contributor.scopusid35741320500tr_TR
dc.contributor.scopusid16679325400tr_TR
dc.date.accessioned2021-12-22T12:27:32Z
dc.date.available2021-12-22T12:27:32Z
dc.date.issued2011-08
dc.description.abstractBackground: Although a variety of different lipid emulsions with varying fatty acid contents have been developed, there are some concerns about the administration of these lipid emulsions because of potential adverse effects, including oxidative stress-related morbidity. The aim of the present study was to evaluate and compare the effects of the standard soybean oil-based and olive oil-based i.v. lipid emulsions (ILE) on oxidative stress, determined by total antioxidant capacity (TAC), and to investigate the safety of the use of these two emulsions in terms of biochemical indices. Methods: In this prospective study, premature infants were randomly assigned to two groups, each group consisting of 32 patients who received parenteral ILE of either 20% olive oil or 20% soybean oil. They were given ILE for 7 days and then were evaluated with regard to TAC. Results: No statistically significant difference was observed between the groups in terms of routine biochemical parameters. TAC for both groups on day 7 was significantly lower compared with that on day 0. Although the decrease in TAC within 7 days of ILE administration was greater in the soybean group compared with that in the olive oil group, it was not statistically significant. Conclusions: Olive oil-based ILE exhibit similar antioxidant activity and can be used as an alternative to soybean oil-based ILE. TAC significantly decreased in infants following administration of either lipid emulsion, and premature infants tolerated either ILE well, both biochemically and clinically.en_US
dc.identifier.citationKöksal, N. vd. (2011). "Comparison of lipid emulsions on antioxidant capacity in preterm infants receiving parenteral nutrition". Pediatrics International, 53(4), 562-566.en_US
dc.identifier.endpage566tr_TR
dc.identifier.issn1328-8067
dc.identifier.issn1442-200X
dc.identifier.issue4tr_TR
dc.identifier.pubmed21342355tr_TR
dc.identifier.scopus2-s2.0-80051960086tr_TR
dc.identifier.startpage562tr_TR
dc.identifier.urihttps://doi.org/10.1111/j.1442-200X.2011.03335.x
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1111/j.1442-200X.2011.03335.x
dc.identifier.urihttp://hdl.handle.net/11452/23465
dc.identifier.volume53tr_TR
dc.identifier.wos000294026800025tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPediatricsen_US
dc.subjectLipid emulsionen_US
dc.subjectOlive oilen_US
dc.subjectPrematureen_US
dc.subjectTotal parenteral nutritionen_US
dc.subjectSoybean oilen_US
dc.subjectSafetyen_US
dc.subject.emtreeClinoleicen_US
dc.subject.emtreeIntralipiden_US
dc.subject.emtreeLipid emulsionen_US
dc.subject.emtreeOlive oilen_US
dc.subject.emtreeSoybean oilen_US
dc.subject.emtreeAntioxidant activityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChemical analysisen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInfanten_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeOxidative stressen_US
dc.subject.emtreeParenteral nutritionen_US
dc.subject.emtreePrematurityen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProspective studyen_US
dc.subject.meshAntioxidantsen_US
dc.subject.meshDouble-blind methoden_US
dc.subject.meshFat emulsions, intravenousen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, newbornen_US
dc.subject.meshInfant, prematureen_US
dc.subject.meshInfant, premature, diseasesen_US
dc.subject.meshMaleen_US
dc.subject.meshOxidative stressen_US
dc.subject.meshParenteral nutritionen_US
dc.subject.meshPlant oilsen_US
dc.subject.meshProspective studiesen_US
dc.subject.meshSoybean oilen_US
dc.subject.scopusLipid Emulsion; Intravenous Feeding; Clinoleicen_US
dc.subject.wosPediatricsen_US
dc.titleComparison of lipid emulsions on antioxidant capacity in preterm infants receiving parenteral nutritionen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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