Effects of green tea on serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic rats

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dc.contributor.buuauthorTaş, Sibel
dc.contributor.buuauthorSarandöl, Emre
dc.contributor.buuauthorZiyanok, Sedef
dc.contributor.buuauthorAslan, Kemal
dc.contributor.buuauthorDirican, Melahat
dc.contributor.departmentUludağ Üniversitesi/Fen Edebiyat Fakültesi/Biyoloji Bölümü.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-2593-7196tr_TR
dc.contributor.researcheridAAH-4272-2021tr_TR
dc.contributor.researcheridABE-1716-2020tr_TR
dc.contributor.researcheridAAG-6985-2021tr_TR
dc.contributor.researcheridABE-6873-2020tr_TR
dc.date.accessioned2021-08-17T08:18:54Z
dc.date.available2021-08-17T08:18:54Z
dc.date.issued2005-12
dc.description.abstractIn recent years, green tea has become a subject of interest because of its beneficial effects on human health. The purpose of this study was to determine the effects of green tea on serum paraoxonase/arylesterase activities and lipoprotein oxidizability in streptozotocin-induced diabetic rats (65 mg/kg [intraperitoneal]). Green tea was given in tap water (2%) for 3 and 6 weeks to control (CGT-3w and CGT-6w) and diabetic (DGT-3w and DGT-6w) rats, and they were compared with the control and diabetic groups (D-3w and D-6w), respectively. Serum insulin level was significantly increased in the DGT-6w group; serum lipid and plasma and tissue malondialdehyde levels were reduced in the DGT-3w and DGT-6w groups. Oxidizability of apolipoprotein B-containing lipoprotein fraction was found to be significantly reduced in the DGT-6w group. Serum total antioxidant capacity showed a significant increase in the CGT-6w and DGT-6w groups. Paraoxonase activity was significantly reduced in the D-3w and D-6w groups and increased in the DGT-6w group. We conclude that green tea might have antilryperlipidernic and antioxidative effects and may slow the progression of atherogenesis by reducing oxidation of lipoproteins and preserving paraoxonase activity.en_US
dc.identifier.citationTaş, S. vd. (2005). "Effects of green tea on serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic rats". Nutrition Research, 25(12), 1061-1074.en_US
dc.identifier.endpage1074tr_TR
dc.identifier.issn0271-5317
dc.identifier.issue12tr_TR
dc.identifier.scopus2-s2.0-28444485706tr_TR
dc.identifier.startpage1061tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.nutres.2005.10.001
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0271531705002289?via%3Dihub
dc.identifier.urihttp://hdl.handle.net/11452/21444
dc.identifier.volume25tr_TR
dc.identifier.wos000234281200004tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.relation.journalNutrition Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRaten_US
dc.subjectOxidative stressen_US
dc.subjectStreptozotocinen_US
dc.subjectDiabetesen_US
dc.subjectGreen teaen_US
dc.subjectParaoxonaseen_US
dc.subjectLow-density-lipoproteinen_US
dc.subjectProtect ldlen_US
dc.subjectParaoxonase activityen_US
dc.subjectLipid-peroxidationen_US
dc.subjectBlack teaen_US
dc.subjectCholesterol leveltr_TR
dc.subjectOxidative stressen_US
dc.subjectLdl oxidationen_US
dc.subjectIn-vitroen_US
dc.subjectPolyphenolsen_US
dc.subjectNutrition & dieteticsen_US
dc.subject.scopusAryldialkylphosphatase; Arylesterase; Human PON1 Proteinen_US
dc.subject.wosNutrition & dieteticsen_US
dc.titleEffects of green tea on serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic ratsen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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