The influence of risk factors in promoting thrombosis during childhood: The role of acquired factors

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dc.contributor.buuauthorGüneş, Adalet Meral
dc.contributor.buuauthorBaytan, Birol
dc.contributor.buuauthorGünay, Ünsal
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Pediatrik Hematoloji Anabilim Dalı.tr_TR
dc.contributor.scopusid24072843300tr_TR
dc.contributor.scopusid6506622162tr_TR
dc.contributor.scopusid6603885274tr_TR
dc.date.accessioned2021-11-29T06:21:00Z
dc.date.available2021-11-29T06:21:00Z
dc.date.issued2006
dc.description.abstractThrombo-embolism in childhood is a multifactorial disorder. The present study is a case-control study that investigated the role of genetic and acquired risk factors in 60 children with thrombosis and compared the results with the controls. Acquired and inherited risk factors precipitating thrombosis were present in 75 and 40% of the thrombotic children, respectively. The most frequent acquired risk factor was infection (58%). Of the genetic factors, factor V G20210A was the most common (38%). The comparison of the genetic and acquired risk factors in thrombotic versus nonthrombotic settings identified that acquired factors played a more significant role in causing thrombosis (OR:14.44; 95% CI: 7.05-29.94, p < .001). This study has clearly suggested that the prevention of acquired risk factors, particularly infection, could decrease the risk of thrombosis in pediatric cases.en_US
dc.identifier.citationGüneş, A. M. vd. (2006). ''The influence of risk factors in promoting thrombosis during childhood: The role of acquired factors''. Pediatric Hematology and Oncology, 23(5), 399-410.en_US
dc.identifier.endpage410tr_TR
dc.identifier.issn0888-0018
dc.identifier.issn1521-0669
dc.identifier.issue5tr_TR
dc.identifier.pubmed16728360tr_TR
dc.identifier.scopus2-s2.0-33746836497tr_TR
dc.identifier.startpage399tr_TR
dc.identifier.urihttps://doi.org/10.1080/08880010600646324
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/08880010600646324
dc.identifier.urihttp://hdl.handle.net/11452/22834
dc.identifier.volume23tr_TR
dc.identifier.wos000237849100004tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherTaylor & Francisen_US
dc.relation.journalPediatric Hematology and Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOncologyen_US
dc.subjectHematologyen_US
dc.subjectPediatricsen_US
dc.subjectThrombosisen_US
dc.subjectGenetic risk factorsen_US
dc.subjectChildrenen_US
dc.subjectAcquired risk factorsen_US
dc.subjectMTHFRen_US
dc.subjectPrevalenceen_US
dc.subjectIschemic-strokeen_US
dc.subjectCommon mutationen_US
dc.subjectThromboembolic complicationsen_US
dc.subjectFactor-V-leidenen_US
dc.subjectProthrombin G20210aen_US
dc.subjectMethylenetetrahydrofolate reductaseen_US
dc.subjectDeep-vein thrombosisen_US
dc.subject.emtreeThrombosisen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeNewbornen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeInfectionen_US
dc.subject.emtreeInfanten_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHeredityen_US
dc.subject.emtreeGeneticsen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeChilden_US
dc.subject.emtreeCase control studyen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAdulten_US
dc.subject.meshTurkeyen_US
dc.subject.meshThrombosisen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshMaleen_US
dc.subject.meshInfectionen_US
dc.subject.meshHumansen_US
dc.subject.meshGenetic predisposition to diseaseen_US
dc.subject.meshFemaleen_US
dc.subject.meshFactor Ven_US
dc.subject.meshChild, preschoolen_US
dc.subject.meshChilden_US
dc.subject.meshCase-control studiesen_US
dc.subject.scopusVenous Thromboembolism; Central Venous Catheters; Thrombosisen_US
dc.subject.wosOncologyen_US
dc.subject.wosHematologyen_US
dc.subject.wosPediatricsen_US
dc.titleThe influence of risk factors in promoting thrombosis during childhood: The role of acquired factorsen_US
dc.typeArticle
dc.wos.quartileQ4en_US

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