Clinical value of a mucin-like carcinoma-associated antigen in monitoring breast cancer patients in comparison with CA 15-3

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dc.contributor.authorMiserez, Andre R.
dc.contributor.authorMüllerbrand, Jan
dc.contributor.authorWalther, Eike
dc.contributor.authorFridrich, Raimund
dc.contributor.authorMäcke, Helmut
dc.contributor.buuauthorGüneş, İlknur
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nükleer Tıp Anabilim Dalı.tr_TR
dc.date.accessioned2021-06-29T07:50:39Z
dc.date.available2021-06-29T07:50:39Z
dc.date.issued1991
dc.description.abstractA new tumour marker, mucin-like carcinoma-associated antigen (MCA), was evaluated in 176 breast cancer patients classified either as free of tumour (NED, n = 141) or as having metastases (PD, n = 35). During the 5 year follow-up, 842 measurements of MCA and 363 measurements of CA 15-3 were done. MCA levels were significantly increased in the PD group (P = 0.0001) but not in the NED group. The sensitivities of the MCA and the CA 15-3 assays were 84% and 78% and the specificities were 81% and 78%, respectively. The negative predictive value of 97% for MCA was significantly higher (P = 0.0001) than the 88% for CA 15-3. Thus the MCA enzyme immunoassay is at least equivalent to the CA 15-3 test and is recommended in the assessment of metastatic spread or tumour recurrence in breast cancer patients.en_US
dc.identifier.citationMiserez, A. R. vd. (1991). ''Clinical value of a mucin-like carcinoma-associated antigen in monitoring breast cancer patients in comparison with CA 15-3''. European Journal of Cancer, 27(2), 126-131.tr_TR
dc.identifier.endpage131tr_TR
dc.identifier.issn0959-8049
dc.identifier.issue2tr_TR
dc.identifier.pubmed1827273tr_TR
dc.identifier.scopus2-s2.0-0025973380en_US
dc.identifier.startpage126tr_TR
dc.identifier.urihttps://doi.org/10.1016/0277-5379(91)90468-S
dc.identifier.urihttp://hdl.handle.net/11452/20892
dc.identifier.volume27tr_TR
dc.identifier.wosA1991FD47000007en_US
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.relation.collaborationYurt dışıtr_TR
dc.relation.journalEuropean Journal of Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMonoclonal-antibodiesen_US
dc.subjectCA 15-3en_US
dc.subjectTumor-markersen_US
dc.subjectDiseaseen_US
dc.subjectDiagnosisen_US
dc.subjectEpitopesen_US
dc.subjectMCAen_US
dc.subjectOncologyen_US
dc.subject.wosOncologyen_US
dc.titleClinical value of a mucin-like carcinoma-associated antigen in monitoring breast cancer patients in comparison with CA 15-3en_US
dc.typeArticle

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