Histological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivo

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dc.contributor.buuauthorCoşkun, Gökçe
dc.contributor.buuauthorKaraca, Esra
dc.contributor.buuauthorÖzyurtlu, Mustafa
dc.contributor.buuauthorÖzbek, Serhat
dc.contributor.buuauthorYermezler, Aysun
dc.contributor.buuauthorÇavuşoğlu, İlkin
dc.contributor.departmentUludağ Üniversitesi/Mühendislik Fakültesi/Tekstil Mühendisliği Bölümü.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Plastik ve Rekonstrüktif Cerrahi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Histoloji ve Embriyoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-1777-3977tr_TR
dc.contributor.orcid0000-0002-9156-2214tr_TR
dc.contributor.researcheridAAS-8480-2020tr_TR
dc.contributor.researcheridAFT-8971-2022tr_TR
dc.contributor.researcheridAAH-5441-2021tr_TR
dc.contributor.scopusid56094840400tr_TR
dc.contributor.scopusid17344029200tr_TR
dc.contributor.scopusid39962152600tr_TR
dc.contributor.scopusid7005245657tr_TR
dc.contributor.scopusid55938747300tr_TR
dc.contributor.scopusid6602910240tr_TR
dc.date.accessioned2022-09-12T08:49:01Z
dc.date.available2022-09-12T08:49:01Z
dc.date.issued2014
dc.description.abstractPoly(vinyl alcohol)/sodium alginate nanofibrous mats were produced by electrospinning method at optimum process parameters. Evaluation of alginate-based electrospun nanofibrous mats as a wound dressing material and their comparison to commercially available wound dressings produced with conventional methods were carried out in vivo. Tissue specimens were examined histopathologically on 4th, 6th, 15th, 21st postoperative days. In contrast to other dressings it was observed that nanofibrous mat could survive on the wound crust in early stages of healing. In terms of epithelization, epidermis characteristics, vascularization and formation of hair follicles, nanofibrous mat showed the best healing performance. This could be explained with presence of nanofibrous mat acting as an artificial skin on the wound region until new tissue regenerated.en_US
dc.identifier.citationCoşkun, G. vd. (2014). "Histological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivo". Bio-Medical Materials and Engineering, 24(2), 1527-1536.en_US
dc.identifier.endpage1536tr_TR
dc.identifier.issn0959-2989
dc.identifier.issn1878-3619
dc.identifier.issue2tr_TR
dc.identifier.pubmed24642979tr_TR
dc.identifier.scopus2-s2.0-84897398165tr_TR
dc.identifier.startpage1527tr_TR
dc.identifier.urihttps://doi.org/10.3233/BME-130956
dc.identifier.urihttp://hdl.handle.net/11452/28642
dc.identifier.volume24tr_TR
dc.identifier.wos000333059600010tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherIos Pressen_US
dc.relation.journalBio-Medical Materials and Engineeringen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.relation.tubitak108M396tr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElectrospinningen_US
dc.subjectNanofiberen_US
dc.subjectAlginateen_US
dc.subjectWound dressingen_US
dc.subjectHistological evaluationen_US
dc.subjectIn vivoen_US
dc.subjectNormal human keratinocytesen_US
dc.subjectNanofibrous membraneen_US
dc.subjectSodium alginateen_US
dc.subjectFibersen_US
dc.subjectEngineeringen_US
dc.subjectMaterials scienceen_US
dc.subjectArtificial organsen_US
dc.subjectBiomaterialsen_US
dc.subjectPolyvinyl alcoholsen_US
dc.subjectTissueen_US
dc.subjectConventional methodsen_US
dc.subjectElectrospinning methoden_US
dc.subjectHistological evaluationen_US
dc.subjectIn-vivoen_US
dc.subjectPost-operative daysen_US
dc.subjectProcess parametersen_US
dc.subjectWound dressing materialsen_US
dc.subjectWound dressingsen_US
dc.subjectNanofibersen_US
dc.subject.emtreeAlginic aciden_US
dc.subject.emtreeCecalgumen_US
dc.subject.emtreeChlorhexidine acetateen_US
dc.subject.emtreeNanofiberen_US
dc.subject.emtreePolyvinyl alcoholen_US
dc.subject.emtreeUnclassified drugen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeConnective tissueen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeElectrospinningen_US
dc.subject.emtreeEpidermisen_US
dc.subject.emtreeEpithelizationen_US
dc.subject.emtreeHair follicleen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeIn vivo studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreePostoperative perioden_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeVascularizationen_US
dc.subject.emtreeWound dressingen_US
dc.subject.emtreeWound healingen_US
dc.subject.meshAlginatesen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBiocompatible materialsen_US
dc.subject.meshGlucuronic aciden_US
dc.subject.meshHexuronic acidsen_US
dc.subject.meshMaleen_US
dc.subject.meshNanofibersen_US
dc.subject.meshPolyvinyl alcoholen_US
dc.subject.meshRabbitsen_US
dc.subject.meshWound healingen_US
dc.subject.scopusChitosan; Electrospinning; Nanofibersen_US
dc.subject.wosEngineering, biomedicalen_US
dc.subject.wosMaterials science, biomaterialsen_US
dc.titleHistological evaluation of wound healing performance of electrospun poly(vinyl alcohol)/sodium alginate as wound dressing in vivoen_US
dc.typeArticle
dc.wos.quartileQ3 (Engineering, biomedical)en_US
dc.wos.quartileQ4 (Materials science, biomaterials)en_US

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