Adjunctive use of the uterine artery resistance index in the preoperative prediction of myometrial invasion in endometrial carcinoma

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dc.contributor.authorYalçın, Ömer T.
dc.contributor.authorÖzalp, Sinan
dc.contributor.buuauthorDevelioğlu, Osman H.
dc.contributor.buuauthorBilgin, Tufan
dc.contributor.buuauthorOzan, Hakan
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.tr_TR
dc.date.accessioned2021-08-23T06:26:25Z
dc.date.available2021-08-23T06:26:25Z
dc.date.issued1999
dc.descriptionBu çalışma, 21-24 Ekim 1997 tarihleri arasında Japonya'da düzenlenen 6. Uluslararası Jinekolojik Kanser Cemiyeti Toplantısında bildiri olarak sunulmuştur.tr_TR
dc.description.abstractObjective. The aim of this study was to evaluate the value of transvaginal ultrasonography (TVUS) and uterine artery flow velocimetry indices in the preoperative detection of deep myometrial invasion in endometrial carcinoma (EC). Methods. Thirty-nine patients with EC underwent TVUS and Doppler flow velocimetry studies, during which endometrial, myometrial, and uterine measurements, presence and depth of myometrial invasion, and pulsatility and resistance indices (PI and RI, respectively) of uterine arteries were noted. TVUS and Doppler findings were correlated with pathological findings obtained by surgical staging. The respective diagnostic accuracies of these variables, and of age and grade, in detecting deep myometrial invasion were assessed with the use of histological findings as the standard. Results. All patients with Grade 3 tumors had deep myometrial invasion, compared to 19% of patients with Grade 1 tumors. The mean age of patients with deep invasion was significantly higher, and their mean PI and RI were significantly lower, than patients with lesser degrees of invasion. While the sensitivity and specificity of TVUS in detecting deep invasion were 37 and 90%, respectively, the corresponding figures for age, grade, and uterine artery RI, found to be independent discriminators of deep invasion, were in the range of 58-84% and 60-70%. The combined use of the latter three parameters resulted in a sensitivity of 100% and specificity of 95%. Conclusions. Our findings indicate that TVUS is unreliable in diagnosing deep myometrial invasion. Detection rates of this pathological feature can be greatly improved, however, with the concomitant use of age, tumor grade, and uterine artery RI.en_US
dc.description.sponsorshipInt Gynecol Cancer Socen_US
dc.identifier.citationDevelioğlu, O. H. vd. (1999). "Adjunctive use of the uterine artery resistance index in the preoperative prediction of myometrial invasion in endometrial carcinoma". Gynecologic Oncology, 72(1), 26-31.en_US
dc.identifier.endpage31tr_TR
dc.identifier.issn0090-8258
dc.identifier.issue1tr_TR
dc.identifier.pubmed9889025tr_TR
dc.identifier.scopus2-s2.0-0032948835tr_TR
dc.identifier.startpage26tr_TR
dc.identifier.urihttps://doi.org/10.1006/gyno.1998.5228
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0090825898952283
dc.identifier.urihttp://hdl.handle.net/11452/21511
dc.identifier.volume72tr_TR
dc.identifier.wos000078147100005tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.indexed.wosCPCISen_US
dc.language.isoenen_US
dc.publisherAcademic Press Inc Elsevier Scienceen_US
dc.relation.collaborationYurt içien_US
dc.relation.journalGynecologic Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOncologyen_US
dc.subjectObstetrics & gynecologyen_US
dc.subjectResistance indextr_TRen_US
dc.subjectEndometrial carcinomaen_US
dc.subjectMyometrial invasionen_US
dc.subjectBlood-flow analysisen_US
dc.subjectTransvaginal ultrasonographyen_US
dc.subjectCanceren_US
dc.subjectDepthen_US
dc.subjectWomenen_US
dc.subjectMrıen_US
dc.subjectCten_US
dc.subject.scopusEndometrial Neoplasms; Diffusion Weighted Imaging; Chemoradiotherapyen_US
dc.subject.wosOncologyen_US
dc.subject.wosObstetrics & gynecologyen_US
dc.titleAdjunctive use of the uterine artery resistance index in the preoperative prediction of myometrial invasion in endometrial carcinomaen_US
dc.typeArticle
dc.typeProceedings Paper
dc.wos.quartileQ2 (Oncology)en_US
dc.wos.quartileQ1 (Obstetrics & gynecology)en_US

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