Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: A 5-year prospective study

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dc.contributor.buuauthorAkdağ, İbrahim
dc.contributor.buuauthorYılmaz, Yusuf
dc.contributor.buuauthorKahvecioğlu, Serdar
dc.contributor.buuauthorBolca, Naile
dc.contributor.buuauthorErcan, İlker
dc.contributor.buuauthorErsoy, Alparslan
dc.contributor.buuauthorGüllülü, Mustafa
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nefroloji ve Romatoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-0710-0923tr_TR
dc.contributor.orcid0000-0003-4518-5283tr_TR
dc.contributor.orcid0000-0002-2382-290Xtr_TR
dc.contributor.researcheridAAH-5054-2021tr_TR
dc.contributor.scopusid8342488100tr_TR
dc.contributor.scopusid22936014300tr_TR
dc.contributor.scopusid55956719500tr_TR
dc.contributor.scopusid13806674200tr_TR
dc.contributor.scopusid6603789069tr_TR
dc.contributor.scopusid35612977100tr_TR
dc.contributor.scopusid6602684544tr_TR
dc.date.accessioned2021-11-26T10:57:40Z
dc.date.available2021-11-26T10:57:40Z
dc.date.issued2008
dc.description.abstractBackground/Aim: Mortality resulting from cardiovascular disease in patients with end-stage renal disease (ESRD) is high. In this study we sought to investigate the clinical value of the malnutrition-inflammation-atherosclerosis (MIA) syndrome for long-term prediction of cardiovascular mortality in patients treated with ESRD. Methods: A total of 42 ESRD patients on hemodialysis were enrolled. Inflammatory markers and nutritional parameters were determined. Carotid atherosclerosis was investigated by ultrasonographically evaluated carotid intima-media thickness (cIMT). Mortality was evaluated at a 5-year follow-up. Results: No correlation was evident between nutritional markers and inflammatory indexes. cIMT was inversely correlated with predialysis serum albumin. In the overall population of 42 patients, 11 (26.2%) died of cardiovascular causes during follow-up. Kaplan-Meier survival curves indicate that cIMT (>= 0.9 mm), C-reactive protein (CRP) (>1 mg/dl), and serum albumin (<3.5 g/dl) predict cardiovascular death in patients with ESRD. Conclusions: We have demonstrated that cIMT, CRP and serum albumin predict long-term mortality in ERSD patients. Our study suggests that further investigation of the MIA syndrome will provide insights into the susceptibility to CVD in this patient group.en_US
dc.identifier.citationAkdag, İ. vd. (2008). ''Clinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: A 5-year prospective study''. Nephron Clinical Practice, 108(2), C99-C105.en_US
dc.identifier.endpageC105tr_TR
dc.identifier.issn1660-2110
dc.identifier.issue2tr_TR
dc.identifier.pubmed18212491tr_TR
dc.identifier.scopus2-s2.0-39549093606tr_TR
dc.identifier.startpageC99tr_TR
dc.identifier.urihttps://doi.org/10.1159/000113526
dc.identifier.urihttps://www.karger.com/Article/Fulltext/113526
dc.identifier.urihttp://hdl.handle.net/11452/22829
dc.identifier.volume108tr_TR
dc.identifier.wos000253247200003tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.journalNephron Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEnd-stage renal diseaseen_US
dc.subjectHemodialysisen_US
dc.subjectCardiovascular diseaseen_US
dc.subjectInflammationen_US
dc.subjectMalnutritionen_US
dc.subjectMortalityen_US
dc.subjectMarkersen_US
dc.subjectNutritionen_US
dc.subjectHemodialysis-patientsen_US
dc.subjectUrology & nephrologyen_US
dc.subject.emtreeAlbuminen_US
dc.subject.emtreeC reactive proteinen_US
dc.subject.emtreeSerum albuminen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAtherosclerosisen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeEchographyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInflammationen_US
dc.subject.emtreeKaplan meier methoden_US
dc.subject.emtreekidney failureen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMalnutritionen_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAnthropometryen_US
dc.subject.emtreeAtherosclerosisen_US
dc.subject.emtreeBlooden_US
dc.subject.emtreeCardiovascular diseaseen_US
dc.subject.emtreeCarotid arteryen_US
dc.subject.emtreeChronic kidney failureen_US
dc.subject.emtreeInflammationen_US
dc.subject.emtreeMalnutritionen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeNonparametric testen_US
dc.subject.emtreePathologyen_US
dc.subject.emtreeProspective studyen_US
dc.subject.emtreeRenal replacement therapyen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeSyndromeen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnthropometryen_US
dc.subject.meshAtherosclerosisen_US
dc.subject.meshC-Reactive proteinen_US
dc.subject.meshCardiovascular diseasesen_US
dc.subject.meshCarotid arteriesen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInflammationen_US
dc.subject.meshKaplan-meiers astimateen_US
dc.subject.meshKidney failure, chronicen_US
dc.subject.meshMaleen_US
dc.subject.meshMalnutritionen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshProspective studiesen_US
dc.subject.meshRenal dialysisen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshSerum albuminen_US
dc.subject.meshStatistics, nonparametricen_US
dc.subject.meshSyndromeen_US
dc.subject.scopusHemodialysis; Wasting; Dialysis Patientsen_US
dc.subject.wosUrology & nephrologyen_US
dc.titleClinical value of the malnutrition-inflammation-atherosclerosis syndrome for long-term prediction of cardiovascular mortality in patients with end-stage renal disease: A 5-year prospective studyen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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