Borderline over tümörlü olgulara klinik yaklaşım
Date
2013-01-02
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Publisher
Uludağ Üniversitesi
Abstract
Çalışmada 2008-2012 yılları arasında, kliniğimizde cerrahi olarak tedavi edilen borderline over tümörü tanılı olguların verileri retrospektif taranarak; klinik özellikleriyle birlikte uygulanan tedavi prosedürlerinin ortaya konulması amaçlanmıştır. Çalışmaya 31 olgu dahil edildi. Olguların, medyan yaşı 40 (18-86) yıl idi ve %74,2’si premenopozaldi (n=23). Medyan tümör çapı 10,5 (3-40) cm’di. En sık postoperatif histolojik tanı; %70,9 (n=22) seröz tip tümörlerdi. Seröz tümorlerin medyan çapı 9 (3-30) cm ve müsinözlerde tümör çapı 20 (4-40) cm’di. Cerrahi öncesinde tümör belirteçleri % 46,4 (n=13) hastada yüksek saptandı. Yirmi yedi hastada frozen kesit uygulandı (%87), frozen uygu lanan olguların % 80,7’inde (21/26), frozen kesitlerinde borderline tümör tanısı konuldu. Operasyon şekli açısından olguların analizinde, hastaların % 54,8’inde (n=17) histerektomi ve bilateral salpingooferektomi uygulanmıştı ve bu olguların % 77,8’i (n=13) 40 yaş ve üzeriydi. Bu bulgular, genç ve fertilite isteği olan olgularda daha sık görülmesi ve Ca 125 değerlerinin genelde normal olması nedeniyle, şüphelenildi ğinde, bu tümörlerde operasyon esnasında frozen kesit alınması ve fertilite koruyucu cerrahi prosedürlerin göz önünde bulundurulması gerektiğini göstermektedir.
In this study, we aimed to determine the borderline ovarian tumors cases that had been treated in our clinic between 2008-2012 retrospective ly, according to clinical features, treatment methods. Thirty one cases were included. Median age was 40 (18-86). Most of the patients were premenopausal (74,2%, n=23). Median tumor size was 10,5 (3-40) cm and 70,9% (n=22) of the patients had serous histologic type. Median tumor size of serous and mucinous tumors were 9 (3-30) cm, 20 (5-40) cm, respectively. Tumor markers were elevated in 46,4 % (n=13) of the patients before the surgery. Twenty-seven patients had frozen section (87%) during surgery. Accuracy rate of the frozen section was 80,7 %(21/26). Whith increasing age ( ≥40 years) 77,8 % of the patients were treated with total abdominal hysterectomy and bilateral salpingooferectomy (n=13). Borderline tumors have perfect prognosis and most of the cases are premenopausal. Fertiliy sparing surgery with frozen section might be chosen in young patients with fertility desire.
In this study, we aimed to determine the borderline ovarian tumors cases that had been treated in our clinic between 2008-2012 retrospective ly, according to clinical features, treatment methods. Thirty one cases were included. Median age was 40 (18-86). Most of the patients were premenopausal (74,2%, n=23). Median tumor size was 10,5 (3-40) cm and 70,9% (n=22) of the patients had serous histologic type. Median tumor size of serous and mucinous tumors were 9 (3-30) cm, 20 (5-40) cm, respectively. Tumor markers were elevated in 46,4 % (n=13) of the patients before the surgery. Twenty-seven patients had frozen section (87%) during surgery. Accuracy rate of the frozen section was 80,7 %(21/26). Whith increasing age ( ≥40 years) 77,8 % of the patients were treated with total abdominal hysterectomy and bilateral salpingooferectomy (n=13). Borderline tumors have perfect prognosis and most of the cases are premenopausal. Fertiliy sparing surgery with frozen section might be chosen in young patients with fertility desire.
Description
Keywords
Borderline over tümörü, Tümör belirteçleri, Histolojik tip, Rekürrens, Sağkalım, Borderline ovarian tumor, Survival, Histologic type, Tumor markers, Recurrence
Citation
Korkmazer, N. S. vd. (2013). "Borderline over tümörlü olgulara klinik yaklaşım". Uludağ Üniversitesi Tıp Fakültesi Dergisi, 39(1), 19-22.