Cytokine gene polymorphism and early graft rejection in liver transplant recipients
dc.contributor.author | Karasu, Zeki | |
dc.contributor.author | Ulukaya, Sezgin | |
dc.contributor.author | Ayanoǧlu, Hilmi Ömer | |
dc.contributor.author | Akyıldız, Murat | |
dc.contributor.author | Tokat, Yaman | |
dc.contributor.buuauthor | Baştürk, Bilkay | |
dc.contributor.buuauthor | Ulukaya, Engin | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/İmmunoloji Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyokimya Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0002-8784-1974 | tr_TR |
dc.contributor.researcherid | AAD-6918-2021 | tr_TR |
dc.contributor.researcherid | K-5792-2018 | tr_TR |
dc.contributor.scopusid | 55910304400 | tr_TR |
dc.contributor.scopusid | 6602927353 | tr_TR |
dc.date.accessioned | 2022-03-22T12:57:00Z | |
dc.date.available | 2022-03-22T12:57:00Z | |
dc.date.issued | 2004-11 | |
dc.description.abstract | Cytokines, which play important roles in allograft rejection, show variable production among individuals. These variations may be related to genetic polymorphisms within the regulatory regions of the cytokine genes. We investigated the association between the role tumor necrosis factor alpha (TNF-α), transforming growth factor-beta (TGF-β), interferon gamma (IFN-γ), interleukin (IL)-10 and IL-6 gene polymorphisms and early graft rejection among liver transplant recipients. Forty-three liver transplant recipients enrolled in this study were divided into 2 groups based on events in the first 2 months posttransplantations, namely, those experiencing at least 1 rejection episode (n = 26) or those without any episode (n = 17). The allele or genotype frequencies of cytokine gene polymorphisms showed no difference between liver recipients with or without nonrejection. In conclusion, there was no significant correlation between early graft rejection and cytokine gene polymorphism of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ in liver transplant recipients. | en_US |
dc.identifier.citation | Karasu, Z. vd. (2004). “Cytokine gene polymorphism and early graft rejection in liver transplant recipients”. Transplantation Proceedings, 36(9), 2791-2795. | en_US |
dc.identifier.endpage | 2795 | tr_TR |
dc.identifier.issn | 0041-1345 | |
dc.identifier.issue | 9 | tr_TR |
dc.identifier.pubmed | 15621151 | tr_TR |
dc.identifier.scopus | 2-s2.0-11144251689 | tr_TR |
dc.identifier.startpage | 2791 | tr_TR |
dc.identifier.uri | https://doi.org/10.1016/j.transproceed.2004.10.034 | |
dc.identifier.uri | http://hdl.handle.net/11452/25277 | |
dc.identifier.volume | 36 | tr_TR |
dc.identifier.wos | 000226142100072 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science | en_US |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.journal | Transplantation Proceedings | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Immunology | en_US |
dc.subject | Surgery | en_US |
dc.subject | Transplantation | en_US |
dc.subject | Necrosis-factor-alpha | en_US |
dc.subject | Renal-allograft rejection | en_US |
dc.subject | Promoter polymorphisms | en_US |
dc.subject | Heart-transplantation | en_US |
dc.subject | Interleukin-10 gene | en_US |
dc.subject | Interferon-gamma | en_US |
dc.subject | TNF-alpha | en_US |
dc.subject | Kidney | en_US |
dc.subject | Association | en_US |
dc.subject | Genotypes | en_US |
dc.subject.emtree | Cyclosporin | en_US |
dc.subject.emtree | Cytokine | en_US |
dc.subject.emtree | Gamma interferon | en_US |
dc.subject.emtree | Interleukin 10 | en_US |
dc.subject.emtree | Interleukin 6 | en_US |
dc.subject.emtree | Methylprednisolone | en_US |
dc.subject.emtree | Steroid | en_US |
dc.subject.emtree | Tacrolimus | en_US |
dc.subject.emtree | Transforming growth factor beta | en_US |
dc.subject.emtree | Tumor necrosis factor alpha | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Clinical article | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Correlation analysis | en_US |
dc.subject.emtree | DNA extraction | en_US |
dc.subject.emtree | DNA polymorphism | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Gene frequency | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Liver graft | en_US |
dc.subject.emtree | Liver graft rejection | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Polymerase chain reaction | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Protein function | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Base sequence | en_US |
dc.subject.mesh | Cytokines | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Gene expression regulation | en_US |
dc.subject.mesh | Genotype | en_US |
dc.subject.mesh | Graft rejection | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Liver transplantation | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Phenotype | en_US |
dc.subject.mesh | Polymorphism, genetic | en_US |
dc.subject.scopus | Kidney Transplantation; Genetic Polymorphism; Graft Rejection | en_US |
dc.subject.wos | Immunology | en_US |
dc.subject.wos | Surgery | en_US |
dc.subject.wos | Transplantation | en_US |
dc.title | Cytokine gene polymorphism and early graft rejection in liver transplant recipients | en_US |
dc.type | Article |
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