Statistical shape analysis of corpus callosum in restless leg syndrome
dc.contributor.author | Güneş, Aygül | |
dc.contributor.author | Durmuş, Yavuz | |
dc.contributor.buuauthor | Sığırlı, Deniz | |
dc.contributor.buuauthor | Özdemir, Senem Turan | |
dc.contributor.buuauthor | Ercan, İlker | |
dc.contributor.buuauthor | Gürsel, Başak Erdemli | |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Temel Bilimler Bölümü/Biyoistatistik Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Anatomi Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Temel Tıp Bilimleri Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı. | tr_TR |
dc.contributor.researcherid | AAA-8734-2021 | tr_TR |
dc.contributor.researcherid | ABF-2367-2020 | tr_TR |
dc.contributor.researcherid | AAH-6568-2021 | tr_TR |
dc.contributor.researcherid | AAA-7472-2021 | tr_TR |
dc.contributor.scopusid | 24482063400 | tr_TR |
dc.contributor.scopusid | 18038353400 | tr_TR |
dc.contributor.scopusid | 6603789069 | tr_TR |
dc.contributor.scopusid | 57209833506 | tr_TR |
dc.date.accessioned | 2023-10-09T08:11:51Z | |
dc.date.available | 2023-10-09T08:11:51Z | |
dc.date.issued | 2020-09-01 | |
dc.description.abstract | Objectives In this study we aimed to investigate corpus callosum shape differences between restless leg syndrome patients and healthy controls, and to determine whether disease severity and duration are indicators for corpus callosum deformation in RLS patients. Methods This study was conducted using the magnetic resonance imaging scans of 33 restless leg syndrome patients and 33 control subjects. Landmarks were marked on the digital images and callosal landmark coordinate data were used to assess shape difference by performing Generalized Procrustes analysis. The shape deformation from controls to the patients was evaluated performing the Thin Plate Spline approach. Results There was a statistically significant shape difference between the groups. Highest deformation was determined at the posterior midbody of the corpus callosum. Growth curve analyses showed that with the increase in disease duration and severity, the CC size decreased. Discussion The present study demonstrated callosal shape differences in restless leg syndrome using a landmark-based geometric morphometric approach, considering the topographic distribution of corpus callosum for the first time. | en_US |
dc.identifier.citation | Sığırlı,D. vd. (2020). "Statistical shape analysis of corpus callosum in restless leg syndrome". Neurological Research, 42(9), 760-766. | en_US |
dc.identifier.endpage | 766 | tr_TR |
dc.identifier.issn | 0161-6412 | |
dc.identifier.issn | 1743-1328 | |
dc.identifier.issue | 9 | tr_TR |
dc.identifier.pubmed | 32496941 | tr_TR |
dc.identifier.scopus | 2-s2.0-85086834317 | tr_TR |
dc.identifier.startpage | 760 | tr_TR |
dc.identifier.uri | https://doi.org/10.1080/01616412.2020.1773631 | |
dc.identifier.uri | https://www.tandfonline.com/doi/full/10.1080/01616412.2020.1773631 | |
dc.identifier.uri | http://hdl.handle.net/11452/34255 | |
dc.identifier.volume | 42 | tr_TR |
dc.identifier.wos | 000542895300001 | tr_TR |
dc.indexed.pubmed | PubMed | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.wos | SCIE | en_US |
dc.language.iso | en | en_US |
dc.publisher | Taylor & Francis | en_US |
dc.relation.collaboration | Sanayi | tr_TR |
dc.relation.journal | Neurological Research | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Statistical shape analysis | en_US |
dc.subject | Corpus callosum | en_US |
dc.subject | Magnetic resonance imaging | en_US |
dc.subject | Somatosensory cortex | en_US |
dc.subject | Restless leg syndrome | en_US |
dc.subject | Topography | en_US |
dc.subject | Matter alterations | en_US |
dc.subject | Postmortem | en_US |
dc.subject | Neurosciences & neurology | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Aged | en_US |
dc.subject.emtree | Allometry | en_US |
dc.subject.emtree | Anthropometry | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Corpus callosum | en_US |
dc.subject.emtree | Disease duration | en_US |
dc.subject.emtree | Disease severity | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Gray matter | en_US |
dc.subject.emtree | Headache | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Migraine | en_US |
dc.subject.emtree | Morphometry | en_US |
dc.subject.emtree | Nuclear magnetic resonance imaging | en_US |
dc.subject.emtree | Restless legs syndrome | en_US |
dc.subject.emtree | Sleep disorder | en_US |
dc.subject.emtree | Adolescent | en_US |
dc.subject.emtree | Diagnostic imaging | en_US |
dc.subject.emtree | Image processing | en_US |
dc.subject.emtree | Pathology | en_US |
dc.subject.emtree | Young adult | en_US |
dc.subject.mesh | Adolescent | en_US |
dc.subject.mesh | Adult | en_US |
dc.subject.mesh | Aged | en_US |
dc.subject.mesh | Corpus callosum | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Image processing | en_US |
dc.subject.mesh | Computer-assisted | en_US |
dc.subject.mesh | Magnetic resonance imaging | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Restless legs syndrome | en_US |
dc.subject.mesh | Young adult | en_US |
dc.subject.scopus | Restless legs syndrome; Nocturnal myoclonus syndrome; Sleep | en_US |
dc.subject.wos | Clinical neurology | en_US |
dc.subject.wos | Neurosciences | en_US |
dc.title | Statistical shape analysis of corpus callosum in restless leg syndrome | en_US |
dc.type | Article | |
dc.wos.quartile | Q3 (Clinical neurology) | en_US |
dc.wos.quartile | Q4 (Neurosciences) | en_US |
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