Clinical experience with systemic cyclosporine A treatment in severe childhood psoriasis

Simple item page
dc.contributor.buuauthorBaşkan, Emel Bülbül
dc.contributor.buuauthorYazıcı, Serkan
dc.contributor.buuauthorTunalı, Şükran
dc.contributor.buuauthorSarıcaoğlu, Hayriye
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Deri ve Zührevi Hastalıklar Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-0144-3263tr_TR
dc.contributor.researcheridAAH-1388-2021tr_TR
dc.contributor.researcheridAAH-2459-2021tr_TR
dc.contributor.scopusid6602518817tr_TR
dc.contributor.scopusid25925620000tr_TR
dc.contributor.scopusid7004191748tr_TR
dc.contributor.scopusid6603722836tr_TR
dc.date.accessioned2022-08-16T12:05:14Z
dc.date.available2022-08-16T12:05:14Z
dc.date.issued2010-07
dc.description.abstractSevere forms of psoriasis including erythrodermic or pustular psoriasis, which require a more aggressive therapeutic approach such as phototherapy or systemic therapies, are rarely seen. Systemic toxicity and long-term safety of these agents are serious concerns in children. Objective: We report our experience on the efficacy and safety of cyclosporine A treatment in 22 patients of childhood psoriasis. Methods: We retrospectively analyzed the records of all patients less than 18 years of age treated with systemic cyclosporine A therapy at our clinic between January 2000 and March 2009. Demographic features as well as other relevant data including previous therapies, the dosage and duration of cyclosporine A therapy, response to treatment and side effects were retrieved from the patients’ records. Results: A total of 22 children were treated with systemic cyclosporine A therapy. Seventeen patients were found to be excellent responders. The mean therapeutic dosage of cyclosporine A was 3.47 ± 0.62 mg/kg/day. The mean duration of cyclosporine A therapy was 5.68 ± 3.29 months. The median time to total clearance of the lesions was 4.0 weeks. Conclusion: We conclude that cyclosporine A therapy is equally effective and safe in pediatric psoriasis patients as in adults.en_US
dc.identifier.citationBaşkan, E. B. vd. (2010). "Clinical experience with systemic cyclosporine A treatment in severe childhood psoriasis". Journal of the European Academy of Dermatology and Venereology, 24(Supplement 4), 1-1.en_US
dc.identifier.endpage1tr_TR
dc.identifier.issn0926-9959
dc.identifier.issueSupplement 4en_US
dc.identifier.scopus2-s2.0-84949579870tr_TR
dc.identifier.startpage1tr_TR
dc.identifier.urihttps://doi.org/10.3109/09546634.2015.1115813
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.3109/09546634.2015.1115813
dc.identifier.urihttp://hdl.handle.net/11452/28206
dc.identifier.volume24tr_TR
dc.identifier.wos000279607700003tr_TR
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.journalJournal of the European Academy of Dermatology and Venereologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAtopic-dermatitisen_US
dc.subjectDermatologyen_US
dc.subjectChildhooden_US
dc.subjectCiclosporine Aen_US
dc.subjectCyclosporine Aen_US
dc.subjectPediatric psoriasisen_US
dc.subjectPsoriasisen_US
dc.subject.emtreeCyclosporin Aen_US
dc.subject.emtreeMethotrexateen_US
dc.subject.emtreePrednisoloneen_US
dc.subject.emtreeCyclosporinen_US
dc.subject.emtreeDermatological agenten_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeChilden_US
dc.subject.emtreeChildhood psoriasisen_US
dc.subject.emtreeChildhood psoriasisen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeDrug dose reductionen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeDrug safetyen_US
dc.subject.emtreeDrug withdrawalen_US
dc.subject.emtreeEvening dosageen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFlu like syndromeen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHypertensionen_US
dc.subject.emtreeHypertrichosisen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical recorden_US
dc.subject.emtreeMonotherapyen_US
dc.subject.emtreeMorning dosageen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreePsoriasisen_US
dc.subject.emtreeRetrospective studyen_US
dc.subject.emtreeSystemic therapyen_US
dc.subject.emtreeTreatment durationen_US
dc.subject.emtreeTreatment responseen_US
dc.subject.emtreePsoriasisen_US
dc.subject.meshAdolescenten_US
dc.subject.meshChilden_US
dc.subject.meshCyclosporineen_US
dc.subject.meshDermatologic agentsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPsoriasisen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.scopusPustulosis Palmoplantaris; Dermatologists; Diaper Rashen_US
dc.subject.wosDermatologyen_US
dc.titleClinical experience with systemic cyclosporine A treatment in severe childhood psoriasisen_US
dc.typeMeeting Abstract
dc.wos.quartileQ1en_US

Files

License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Web of Science
Scopus