Invasive fungal infections in renal transplant recipients: Epidemiology and risk factors

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dc.contributor.buuauthorŞahin, Sezin Zorlu
dc.contributor.buuauthorAkalın, Halis
dc.contributor.buuauthorErsoy, Alparslan
dc.contributor.buuauthorYıldız, Abdulmecit
dc.contributor.buuauthorOcakoğlu, Gökhan
dc.contributor.buuauthorÇetinoğlu, Ezgi Demirdöven
dc.contributor.buuauthorDizdar, Oğuzhan Sıtkı
dc.contributor.buuauthorKazak, Esra
dc.contributor.buuauthorEner, Beyza
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Mikrobiyoloji ve Enfeksiyon Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Nefroloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-4803-8206tr_TR
dc.contributor.orcid0000-0002-0710-0923tr_TR
dc.contributor.researcheridAAG-8459-2021tr_TR
dc.contributor.researcheridAAG-8523-2021tr_TR
dc.contributor.researcheridAAH-5180-2021tr_TR
dc.contributor.researcheridAAH-5054-2021tr_TR
dc.contributor.researcheridAAU-8952-2020tr_TR
dc.contributor.scopusid56537830100tr_TR
dc.contributor.scopusid57207553671tr_TR
dc.contributor.scopusid35612977100tr_TR
dc.contributor.scopusid56256977500tr_TR
dc.contributor.scopusid15832295800tr_TR
dc.contributor.scopusid57189524206tr_TR
dc.contributor.scopusid55202193000tr_TR
dc.contributor.scopusid24921238200tr_TR
dc.contributor.scopusid15053025300tr_TR
dc.date.accessioned2022-06-14T08:26:38Z
dc.date.available2022-06-14T08:26:38Z
dc.date.issued2015-08
dc.description.abstractInvasive fungal infections are a major cause of morbidity and mortality among renal transplant recipients. The aim of this study was to investigate the frequency and risk factors for fungal infections in renal transplant recipients. We retrospectively evaluated all kidney transplant recipients at our center from December 1988 to June 2010 for the epidemiology, spectrum, risk factors, and mortality of invasive fungal infections. In 32 patients (10.30 %), at least one fungal infection developed after the transplantation. The most common pathogens causing fungal infections in our patients were Candida spp. and Aspergillus spp. The independent risk factors associated with invasive fungal infection episodes were antibiotic treatment within the last 3 months (OR 15.88, 95 % CI 3.90-64.73, p < 0.001), cytomegalovirus infection (OR 18.54, 95 % CI 9.01-38.17, p < 0.001), and the presence of diabetes mellitus (OR 6.01, 95 % CI 2.95-12.25, p < 0.001). Mortality was significantly higher among patients with fungal infections than among other patients (53.10 and 17.80 %, respectively; p < 0.001). It is difficult to diagnose and treat fungal infections early, and it can be useful to determine independent risk factors in order to identify and treat high-risk patients.en_US
dc.identifier.citationŞahin, S. Z. vd. (2015). "Invasive fungal infections in renal transplant recipients: Epidemiology and risk factors". Mycopathologia, 180(1-2), 43-50.en_US
dc.identifier.endpage50tr_TR
dc.identifier.issn0301-486X
dc.identifier.issue1-2tr_TR
dc.identifier.pubmed25739669tr_TR
dc.identifier.scopus2-s2.0-84937513709tr_TR
dc.identifier.startpage43tr_TR
dc.identifier.urihttps://doi.org/10.1007/s11046-015-9875-4
dc.identifier.urihttps://link.springer.com/article/10.1007/s11046-015-9875-4
dc.identifier.urihttp://hdl.handle.net/11452/27142
dc.identifier.volume180tr_TR
dc.identifier.wos000358164600006tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.journalMycopathologiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCandida infectionsen_US
dc.subjectFungal infectionen_US
dc.subjectInvasive aspergillosisen_US
dc.subjectKidney transplantationen_US
dc.subjectCryptococcus-neoformansen_US
dc.subjectCandida-albicansen_US
dc.subjectAspergillosisen_US
dc.subjectCalcineurinen_US
dc.subjectGalactomannanen_US
dc.subjectMortalityen_US
dc.subjectComplicationsen_US
dc.subjectZygomycosisen_US
dc.subjectVirulenceen_US
dc.subjectMycologyen_US
dc.subjectAspergillusen_US
dc.subjectCandidaen_US
dc.subjectCytomegalovirusen_US
dc.subject.emtreeAntiinfective agenten_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeClassificationen_US
dc.subject.emtreeComplicationen_US
dc.subject.emtreeCytomegalovirus infectionen_US
dc.subject.emtreeDiabetes mellitusen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFungemiaen_US
dc.subject.emtreeFungusen_US
dc.subject.emtreeGraft recipienten_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeIsolation and purificationen_US
dc.subject.emtreeKidney transplantationen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMicrobiologyen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeRetrospective studyen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeSurvivalen_US
dc.subject.emtreeYoung adulten_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnti-bacterial agentsen_US
dc.subject.meshCytomegalovirus infectionsen_US
dc.subject.meshDiabetes complicationsen_US
dc.subject.meshFemaleen_US
dc.subject.meshFungemiaen_US
dc.subject.meshFungien_US
dc.subject.meshHumansen_US
dc.subject.meshKidney transplantationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshSurvival analysisen_US
dc.subject.meshTransplant recipientsen_US
dc.subject.meshYoung adulten_US
dc.subject.scopusSystemic Mycosis; Aspergillosis; Transplant Recipientsen_US
dc.subject.wosMycologyen_US
dc.titleInvasive fungal infections in renal transplant recipients: Epidemiology and risk factorsen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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