Risk of recurrence after first unprovoked tonic-clonic seizure in adults

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dc.contributor.buuauthorBora, İbrahim Hakkı
dc.contributor.buuauthorSeçkin, Basri
dc.contributor.buuauthorZarifoğlu, Mehmet
dc.contributor.buuauthorTuran, Faruk
dc.contributor.buuauthorSadıkoğlu, Sadık
dc.contributor.buuauthorOğul, Erhan
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.tr_TR
dc.date.accessioned2021-06-21T12:32:57Z
dc.date.available2021-06-21T12:32:57Z
dc.date.issued1995
dc.description.abstractThe likelihood of seizure recurrence after a first unprovoked seizure has profound social, vocational and emotional implications for the patients. Recurrence rates have varied between 27% and 71% in various studies, and the management of patients with a single unprovoked seizure is a controversial topic. In this prospective study we investigated the influence of age, sex, family history, EEG patterns, and anticonvulsant drug (ACD) therapy on seizure recurrence after a first unprovoked tonic-clonic seizure in adults. For this purpose, between October 1988 and January 1991, we studied adult patients who had experienced their after unprovoked tonic-clonic seizure within last 2 months before neurological consultation, and followed them until June 1993. There were 147 patients who met the criteria for inclusion. Overall cumulative recurrence rates were 31.8% by 6 months, 41.3% by 1 year, 44.1% by 2 years, 42.2% by 3 years, and 45.2% by 4 years. Among the risk factors that were evaluated, the time of the day at which the initial seizure occurred was associated significantly (P < 0.05) with seizure recurrence. In our series, 62 patients received ACD and 85 did not. We did not find a significant difference in recurrence rate with regard to ACD therapy. Our results are comparable with those of studies reported preeviously and suggest that the majority of recurrences after a first unprovoked seizure were seen in the first year (in our series 89% of all recurrences). In our study there was no significant predictor of seizure recurrence, except the time of day at which the initial seizure occurred.tr_TR
dc.identifier.citationBora, İ. H. vd. (1995). ''Risk of recurrence after first unprovoked tonic-clonic seizure in adults''. Journal of Neurology, 242(3), 157-163.tr_TR
dc.identifier.endpage163tr_TR
dc.identifier.issn0340-5354
dc.identifier.issue3tr_TR
dc.identifier.pubmed7751859tr_TR
dc.identifier.scopus2-s2.0-0028798739tr_TR
dc.identifier.startpage157tr_TR
dc.identifier.urihttps://doi.org/10.1007/BF00936889
dc.identifier.urihttps://link.springer.com/content/pdf/10.1007/BF00936889.pdf
dc.identifier.urihttp://hdl.handle.net/11452/20680
dc.identifier.volume242tr_TR
dc.identifier.wosA1995QG98500008tr_TR
dc.indexed.pubmedPubmedtr_TR
dc.indexed.scopusScopustr_TR
dc.indexed.wosSCIEtr_TR
dc.language.isoentr_TR
dc.publisherSpringer Verlagtr_TR
dc.relation.journalJournal of Neurologytr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccesstr_TR
dc.subjectEpilepsytr_TR
dc.subjectSeizure recurrencetr_TR
dc.subjectAnticonvulsant therapytr_TR
dc.subject1st seizuretr_TR
dc.subjectEpilepsytr_TR
dc.subjectChildhoodtr_TR
dc.subjectPrognosistr_TR
dc.subject.wosClinical neurologytr_TR
dc.titleRisk of recurrence after first unprovoked tonic-clonic seizure in adultstr_TR
dc.typeArticle

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