Effects of a hypertonic saline solution and dextran 70 combination in the treatment of diarrhoeic dehydrated calves

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dc.contributor.buuauthorŞentürk, Sezgin
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/İç Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.scopusid56257771200tr_TR
dc.date.accessioned2022-04-27T05:36:47Z
dc.date.available2022-04-27T05:36:47Z
dc.date.issued2003-03
dc.description.abstractThirty dehydrated diarrheic calves aged 2-45 days were used to study the effects of small volume intravenous 7.2% hypertonic saline and 6% dextran 70 solution in combination with alkalinising oral fluids and to compare this therapy with the large volume intravenous isotonic saline with alkalinising oral fluid treatment. This study included a total of 30 diarrhoeic dehydrated calves aged 2-45 days. After routine clinical and haematological examinations, the calves were allotted to two treatment groups. Isotonic saline solution (32 ml/kg, i.v.) with an oral electrolyte solution (22 ml/kg, p.o.) were administered to group I (control), and the combination of 7.2% hypertonic saline in 6% dextran 70 solutions (HSD) (4 ml/kg, i.v.) with an oral electrolyte solution (50 ml/kg, p.o.) were administered to group II (test). Additionally, an oral electrolyte solution (50 ml/kg, p.o.) was readministered to both groups at 12 h of the study. The clinical and haematological examinations of all calves were performed both before and after the treatment at the 1/2, 1, 2, 4, 12 and 24 h. The capillary refill time, peripheral pulse quality, dehydration degrees, mental status, haematocrit rates, haemoglobin and plasma values after treatment were found to be statistically different compared with the values before treatment. In comparison with group I, group II is observed to have shorter capillary refill time at 1, 4 and 12 h (P < 0.001) and better peripheral pulse quality at 1/2 (P < 0.05), 1, 2, 4 and 12 h (P < 0.001). Moreover, the degree of dehydration in group II, was significantly improved at 2 (P < 0.01), 4 and 12 h. Results of the study indicated that administration of low volumes of hypertonic sodium chloride and dextran 70 solution combinations with oral electrolyte solutions was concluded as quicker, practical, economical and most importantly an effective way for the treatment of dehydrated diarrhoeic calves.en_US
dc.identifier.citationŞentürk, S. (2003). “Effects of a hypertonic saline solution and dextran 70 combination in the treatment of diarrhoeic dehydrated calves”. Journal of Veterinary Medicine Series A-Physiology Pathology Clinical Medicine, 50(2), 57-61.en_US
dc.identifier.endpage61tr_TR
dc.identifier.issn0931-184X
dc.identifier.issue2tr_TR
dc.identifier.pubmed12667194tr_TR
dc.identifier.scopus2-s2.0-0037645089tr_TR
dc.identifier.startpage57tr_TR
dc.identifier.urihttps://doi.org/10.1046/j.1439-0442.2003.t01-1-00488.x
dc.identifier.urihttp://hdl.handle.net/11452/26126
dc.identifier.volume50tr_TR
dc.identifier.wos000181345900001tr_TR
dc.indexed.pubmedPubMeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherWiley-Blackwell Publishingen_US
dc.relation.journalJournal of Veterinary Medicine Series A-Physiology Pathology Clinical Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVeterinary sciencesen_US
dc.subjectCritical needen_US
dc.subjectColloidsen_US
dc.subject.emtreeAnimalen_US
dc.subject.emtreeAnimal diseaseen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCattleen_US
dc.subject.emtreeCattle diseaseen_US
dc.subject.emtreeClinical trialen_US
dc.subject.emtreeControlled clinical trialen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDehydrationen_US
dc.subject.emtreeDiarrheaen_US
dc.subject.emtreeHemodynamicsen_US
dc.subject.emtreeIntravenous drug administrationen_US
dc.subject.emtreeNewbornen_US
dc.subject.emtreeOral drug administrationen_US
dc.subject.emtreePathophysiologyen_US
dc.subject.emtreeRandomized controlled trialen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.emtreeDextranen_US
dc.subject.emtreeOral rehydration solutionen_US
dc.subject.emtreeSodium chlorideen_US
dc.subject.meshAdministration, oralen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnimals, newbornen_US
dc.subject.meshCattleen_US
dc.subject.meshCattle diseasesen_US
dc.subject.meshDehydrationen_US
dc.subject.meshDextransen_US
dc.subject.meshDiarrheaen_US
dc.subject.meshHemodynamic processesen_US
dc.subject.meshInfusions, intravenousen_US
dc.subject.meshRehydration solutionsen_US
dc.subject.meshSaline solution, hypertonicen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.scopusCalves; Milk Replacer; Diarrheaen_US
dc.subject.wosVeterinary sciencesen_US
dc.titleEffects of a hypertonic saline solution and dextran 70 combination in the treatment of diarrhoeic dehydrated calvesen_US
dc.typeArticle
dc.wos.quartileQ3en_US

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