Yerel steroidlerin deri kalınlığı ve bazı sistemik parametreler üzerindeki etkileri
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Date
1988
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Publisher
Uludağ Üniversitesi
Abstract
Yaygın psoriasis vulgarisli hastalara güçlü fluorlu steroidli merhem sürülerek ne gibi yan etkilere neden olabileceği araştırıldı. Tedaviden önce ve tedavinin 1., 3., 5. ve 21 . günü alınan kan örneklerinde insulin, açlık kan şekeri, kortizol düzeyleri, lökosit, mutlak lenfosit ve mutlak nötrofil değerleri incelendi. Çalışmamızda herhangi bir yan etki saptanamadı . Tedavi amacıyla kullanılan fluorlu steroidli merhem sağlam deride herhangi bir yan etkiye neden olmadığı, ancak psoriasis plaklarında , plakların iyileşmesine bağlı olarak anlamlı bir atrofiye neden olduğu gözlendi.
We have treated the patients who are diagnosed as generalized psoriasis vulgaris with topical steroids fluorinated steroids) and searched for the side effects of this treatment. We've investigated in the blood samples of the blood samples of the patients insulin, fasting blood sugar, cortisol levels and leukocytes, absolute-lymphocyte and neutrophil counts before the treatment and in the lst, 3rd, 5 th and 21st day s of the treatment. In our investigation we didn 't recognise any systemic side effects. We concluded that topical steroids fluorinated) when used therapeutically don't have any side effects on the normal skin nonetheless cause significant atrophy on the psoriatic plaques due to the recovery of the plagues.
We have treated the patients who are diagnosed as generalized psoriasis vulgaris with topical steroids fluorinated steroids) and searched for the side effects of this treatment. We've investigated in the blood samples of the blood samples of the patients insulin, fasting blood sugar, cortisol levels and leukocytes, absolute-lymphocyte and neutrophil counts before the treatment and in the lst, 3rd, 5 th and 21st day s of the treatment. In our investigation we didn 't recognise any systemic side effects. We concluded that topical steroids fluorinated) when used therapeutically don't have any side effects on the normal skin nonetheless cause significant atrophy on the psoriatic plaques due to the recovery of the plagues.
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Keywords
Yerel steroidler, Deri kalınlığı, Sistemik parametreler, Systemic parameters, Skin thickness, Local steroids
Citation
Tunalı, Ş. (1988). ''Yerel steroidlerin deri kalınlığı ve bazı sistemik parametreler üzerindeki etkileri''. Uludağ Üniversitesi Tıp Fakültesi Dergisi, 15(3), Supplementum 4, 1-15.