A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide

Simple item page
dc.contributor.authorÖzet, Ahmet
dc.contributor.authorAtaergin, S.
dc.contributor.authorArpacı, F.
dc.contributor.authorÖzturk, Bülent
dc.contributor.authorArpacı, Fikret
dc.contributor.authorÖztürk, M.
dc.contributor.authorKomürcü, S.
dc.contributor.authorKuzhan, O.
dc.contributor.buuauthorKanat, O.
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi.tr_TR
dc.contributor.scopusid6602187347tr_TR
dc.date.accessioned2022-01-17T08:06:01Z
dc.date.available2022-01-17T08:06:01Z
dc.date.issued2006-06
dc.description.abstractScalp angiosarcoma is a rare and highly malignant tumour originating from endothelial cells of vessels and occurring predominantly in elderly men. Its prognosis is poor and the 5-year survival rate of patients is reported to be 12–33% [1]. Complete surgical excision with wide margins remains the cornerstone of therapy for localised tumours. Additional radiotherapy may provide improved local control. Given the rarity of this tumour, an optimum chemotherapy regimen has not yet been defined for metastatic cases. Here we report a case of scalp angiosarcoma with local recurrence and distant metastases which was successfully treated with a combination chemotherapy consisting of adriamycin, cisplatin, ifosfamide and mesna (APIM). A 24-year-old man presented to a plastic surgeon in January 2005 with a painless nodule on the scalp measuring 3 cm in diameter. Surgical total excision of the nodule was carried out, providing a negative surgical margin (2 cm). The diagnosis of angiosarcoma was confirmed pathologically. An X-ray of the scull, magnetic resonance imaging of the brain and computed tomography of the neck, thorax and abdomen revealed no evidence of local or distant metastases at the time of diagnosis. The patient was not given any adjuvant therapy. Five months after the surgery, the patient developed two new angiosarcoma lesions (1.5 and 2 cm in diameter) on different sites of the scalp. In addition, computed tomography of the neck and chest revealed conglomerate lymph nodes on the left side of the neck and five small metastatic nodules, up to 1.5 cm greatest dimension in bilateral lung fields.en_US
dc.identifier.citationKanat, O. vd. (2006). ''A case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamide''. Clinical Oncology, 18(5), 426-427.en_US
dc.identifier.endpage427tr_TR
dc.identifier.issn0936-6555
dc.identifier.issue5tr_TR
dc.identifier.pubmed16817336tr_TR
dc.identifier.scopus2-s2.0-33646118234tr_TR
dc.identifier.startpage426tr_TR
dc.identifier.urihttps://doi.org/10.1016/j.clon.2006.03.002
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0936655506000951
dc.identifier.urihttp://hdl.handle.net/11452/24116
dc.identifier.volume18tr_TR
dc.identifier.wos000237988700012tr_TR
dc.indexed.pubmedPubmeden_US
dc.indexed.scopusScopusen_US
dc.indexed.wosSCIEen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.collaborationSanayitr_TR
dc.relation.journalClinical Oncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOncologyen_US
dc.subjectMesnaen_US
dc.subjectIfosfamideen_US
dc.subjectDoxorubicinen_US
dc.subjectCisplatinen_US
dc.subjectSkin neoplasmsen_US
dc.subjectScalpen_US
dc.subjectMaleen_US
dc.subjectIfosfamideen_US
dc.subjectHumansen_US
dc.subject.emtreeMesnaen_US
dc.subject.emtreeIfosfamideen_US
dc.subject.emtreeDoxorubicinen_US
dc.subject.emtreeCisplatinen_US
dc.subject.emtreeSkin surgeryen_US
dc.subject.emtreeSkin noduleen_US
dc.subject.emtreeScalp tumoren_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeNeutropeniaen_US
dc.subject.emtreeNauseaen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeLymph node metastasisen_US
dc.subject.emtreeLung metastasisen_US
dc.subject.emtreeLetteren_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeDrug tolerabilityen_US
dc.subject.emtreeComputer assisted tomographyen_US
dc.subject.emtreeCase reporten_US
dc.subject.emtreeCancer recurrenceen_US
dc.subject.emtreeCancer combination chemotherapyen_US
dc.subject.emtreeAngiosarcomaen_US
dc.subject.emtreeAdvanced canceren_US
dc.subject.emtreeAdulten_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshSkin neoplasmsen_US
dc.subject.meshScalpen_US
dc.subject.meshMaleen_US
dc.subject.meshIfosfamideen_US
dc.subject.meshHumansen_US
dc.subject.meshHemangiosarcomaen_US
dc.subject.meshHead and neck neoplasmsen_US
dc.subject.meshDoxorubicinen_US
dc.subject.meshCisplatinen_US
dc.subject.meshAntineoplastic combined chemotherapy protocolsen_US
dc.subject.meshAdulten_US
dc.subject.scopusAngiosarcoma; Scalp; Vascular Tumoren_US
dc.subject.wosOncologyen_US
dc.titleA case of advanced scalp angiosarcoma successfully treated with combination chemotherapy of adriamycin, cisplatin and ifosfamideen_US
dc.typeLetter
dc.wos.quartileQ4en_US

Files

License bundle
Now showing 1 - 1 of 1
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

Web of Science
Scopus