Hospital-acquired anemia in chronic kidney disease

Abstract

Chronic kidney disease (CKD) has become an important public health problem with the increasing incidence and prevalence of life with increasing life expectancy in developed countnes and increasing the life expectancy in our country as well as facilitating access to health services. There was no study on hospital-acquired anemia (HEA) in patients with CKD. The aim of our study was to determine the prevalence of HEA and the factors affecting the development of HEA in patients with chronic renal failure who did not undergo hemodialysis. This study was performed prospectively between March and September 2014 at the Nephrology Clinic, Faculty of Medicine, Balikesjr University. Patients aged between 18- 80 years and 100 without any renal replacement therapy were included in the study. Of the 100 patients included in the study, 48 were female and 52 were male. The mean age in the group was 61.58, the mean age was 62.02 in males and 60.90 in females. Of the patients included in the study, 47 had diabetes mellitus, 73 had hypertension, 18 had atherosclerotic heart disease, 8 had heart failure, 11 patients had hypothyroidism, 2 had hyperthyroidism, 6 had chronic obstructive pulmonary disease. 59 had metabolic syndrome was detected. The patient’s hemoglobin level decreased by 0.5 g/dl after the hospitalization was defined as HEA positive, and the reduction of less than 0.5 g/dl was defined as HEA negative. According to our study, hypothyroidism and CKD stage were found to be significantly related to the presence of HEA in the HEA positive group. All 11 patients with hypothyroidism developed HEA. The increase in the number of patients with HEA with an increased CKD stage is evident (for hypothyroidism and CKD stage p=0.021). Anticoagulant use and CKD were significantly associated with the presence of HEA (p=0.025 for anticoagulant use and p=0.002 for CKD). The prevalence of HEA was found to be high in CKD. When we investigated the factors that may affect HEA development in CKD patients, only CKD stage and hypothyroidism -were significantly associated with HEA development. Comparison of these results with healthy individuals; To investigate the effect on prognosis, mortality, and morbidity, we think that a large patient series should be studied.