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KASAPOĞLU, FİKRET

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KASAPOĞLU

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FİKRET

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2019 - 201912020 - 20211
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    Turkish guideline for diagnosis and treatment of allergic rhinitis (ART)
    (Galenos Yayınevi, 2021-05-01) Ecevit, Mustafa Cenk; Özcan, Müge; Can, İlknur Haberal; Tatar, Emel Cadalli; Özer, Serdar; Esen, Erkan; Atan, Doğan; Gode, Sercan; Elsurer, Cağdaş; Eryılmaz, Aylin; Coşkun, Berna Uslu; Yazıcı, Zahide Mine; Dinç, Mehmet Emre; Özdoğan, Fatih; Günhan, Kıvanç; Bilal, Nagihan; Korkut, Arzu Yasemin; Kasapoğlu, Fikret; Türk, Bilge; Server, Ela Araz; Çelebi, Özlem Önerci; Şimşek, Tuğçe; Kum, Rauf Oğuzhan; Adalı, Mustafa Kemal; Eren, Erdem; Aslıer, Nesibe Gül Yüksel; Bayındır, Tuba; Çetin, Aslı Çakır; Göker, Ayşe Enise; Güvenç, Işıl Adadan; Köseoğlu, Sabri; Özler, Gül Soylu; Şahin, Ethem; YIlmaz, AslI şahin; Güne, Ceren; Yıldırım, Gökçe Aksoy; Oca, Bülent; Durmuşoğlu, Mehmet; Kantekin, Yunus; Özmen, Suay; Kubat, Gözde Orhan; Sanal, Serap Koybaşı; Altuntaş, Emine Elif; Selçuk, Adın; Yazıcı, Haşmet; Baklacı, Deniz; Yaylacı, Atılay; Hancı, Deniz; Doğan, Sedat; Fidan, Vural; Uygur, Kemal; Keleş, Nesil; Çingi, Cemal; Topuz, Bülent; Çanakcıoğlu, Şalih; Önerci, Metin; KASAPOĞLU, FİKRET; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.; FDZ-6520-2022
    Object: To prepare a national guideline for Oto-rhinolaryngologist who treat allergic rhinitis patientsMethods: The study was conducted by three authors, namely the writing support team. The support team made the study plan, determined the writing instructions, chose the subgroups including the advisory committee, the advisors for authors and the authors. A workshop was organized at the very beginning to explain the details of the study to the team. Advisors took the chance to meet their coworkers in their subgroups and determined the main headings and subheadings of the guideline, together with the authors. After key words were determined by the authors, literature search was done in various databases. The authors keep in touch with the advisors and the advisors with the advisory committee and the support group at every stage of the study. National and International published articles as well as the abstracts of unpublished studies, imperatively presented in National Congresses, were included in this guideline. Only Guideline and meta-analyses published in last seven years (2013- 2017) and randomized controlled studies published in last two years (2015- 2017) were included. After all work was completed by the subgroups, support team brought all work together and edited the article.Results: A detailed guideline about all aspects of allergic rhinitis was created.Conclusion: The authors believe that this guideline will enable a compact and up-to-date information on allergic rhinitis to healthcare professionals. This guideline is the first in the field of Otolaryngology in Turkey. It should be updated at regular intervals.
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    Publication
    Relationship with excessive daytime sleepiness and serum substance P levels in OSAS patients and the effect of PAP treatment
    (Springer Japan, 2019-07-01) Güçlu, Özge Aydın; Ursavaş, Ahmet; Kasapoğlu, Fikret; Özarda, Yeşim; Bozyiğit, Cengiz; Ocakoğlu, Gökhan; Karadağ, Mehmet; AYDIN GÜÇLÜ, ÖZGE; URSAVAŞ, AHMET; KASAPOĞLU, FİKRET; ÖZARDA, YEŞİM; BOZYİĞİT, CENGİZ; OCAKOĞLU, GÖKHAN; KARADAĞ, MEHMET; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Kulak Burun Boğaz Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyokimya Anabilim Dalı.; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0003-1005-3205; 0000-0003-2215-6973; 0000-0002-1114-6051; 0000-0002-9027-1132; AAI-3877-2021; AAI-3169-2021; AAH-5180-2021; AAL-8873-2021; HLG-6346-2023; AAG-8744-2021; AAG-9930-2019; AAE-1623-2022
    Obstructive sleep apnea syndrome (OSAS) is a commonly seen disorder characterized by repeated episodes of upper airway obstruction during sleep leading to intermittent hypoxemia or arousal. We aim to evaluate the effects of positive airway pressure (PAP) treatment on daytime sleepiness and serum Substance P (SP) levels in OSAS patients. Seventy-one consecutive patients with newly diagnosed OSAS and 19 non-apneic control subjects were enrolled to the study. PAP treatment indicated subjects were re-evaluated after 3 months of treatment. Morning SP levels of OSAS patients and Epworth sleepiness scale (ESS) were assessed at the beginning and then after 3 months of PAP treatment. Of the patients 71 (78.9%) were male and 19 (21.1%) were female, with a median age of 45 [20-62]. The levels of SP in the OSAS group were significantly lower than the snorer group and a significant correlation was not found between serum levels of SP and ESS. SP levels were negatively correlated with AHI. The baseline SP median was 336.1pg/mL [121.6-536.1], while the 3rd month SP median was 213.1pg/mL [103.5-727.6]. Serum SP values were found to have significantly decreased at 3months (p<0.0001). Statistically significant correlation was not found between percentage of ESS change and the percentage of SP change. It can be assumed that the SP level is reduced as part of the compensation mechanism in OSAS cases and supporting this mechanism, the PAP therapy further reduces the SP value by relieving the cases from apnea and the intermittent hypoxia burden.