Person: TURAN, SERKAN
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
TURAN
First Name
SERKAN
Name
5 results
Search Results
Now showing 1 - 5 of 5
Publication Violence against the doctor in the developing countries during covid-19 pandemic. mental health linkages(Medicinska Naklada, 2021-01-01) Shoib, Sheikh; Arafat, S. M. Yasir; Gupta, Anoop Krishana; Ullah, Irfan; Turan, Serkan; Turan, Serkan; TURAN, SERKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; 0000-0002-6548-0629; HKE-9636-2023Publication Impaired theory of mind and emotion recognition in pediatric bipolar disorder: A systematic review and meta-analysis(Pergamon-Elsevier Science Ltd, 2021-04-15) Halac, Eren; Ciray, Remzi Ogulcan; Tuncturk, Mustafa; Agac, Nilay; Elmas, Fatma Nur; Rosson, Stella; Ermis, Cagatay; Turan, Serkan; TURAN, SERKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Psikiyatri Anabilim Dalı.; 0000-0003-2864-613X; 0000-0002-6548-0629; 0000-0003-3928-3194; 0000-0002-8554-3519; HKE-9636-2023; AFO-6356-2022; GRY-0250-2022Background: Social cognition is impaired in patients with severe mental disorders. We aimed to investigate impairments in social cognition in youth with pediatric bipolar disorder (PBD) through a systematic review of the literature and the meta-analysis.Method: Following the PRISMA guidelines, we searched in PubMed, Scopus, and Cochrane CENTRAL for studies reporting on the theory of mind (ToM) and emotion recognition (ER) abilities of patients with PBD compared to healthy controls (HC). We conducted a random-effects model meta-analysis for the contrast between PBD and HC. Subgroup and meta-regression analyses were conducted for demographic and clinical variables as appropriate.Results: A total of thirteen studies involving 429 patients with PBD and 394 HC were included. Patients with PBD had significantly poorer social cognitive abilities (Hedges' g for ER, g = -0.74, CI = -0.91, -0.57; and for ToM, g = -0.98, CI = -1.41 to -0.55). Subgroup analysis also revealed significant impairment in ER for patients in a euthymic state (g = -0.75). Age, gender, sample size, the severity of mood symptoms, estimated IQ, the frequencies of bipolar-I disorder, attention-deficit hyperactivity disorder, medications, study quality and euthymia did not moderate the difference in meta-regression. Heterogeneity was low in all analyses and there was no evidence for publication bias.Conclusion: The results of this meta-analysis supported the notion that PBD is associated with a deficit in social cognitive abilities at a medium to a large level. Impairments in social cognition could be an illness-related trait of PBD. Meta-regression results did not find a moderator of the deficits in social cognition.Publication Selective serotonin reuptake inhibitors and manic switch: A pharmacovigilance and pharmacodynamical study(Elsevier, 2021-10-16) Çıray, R. Oğulcan; Halaç, Eren; Turan, Serkan; Tunçtürk, Mustafa; Özbek, Mutlu; Ermiş, Çağatay; TURAN, SERKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk ve Ergen Psikiyatrisi Anabilim Dalı.; 0000-0002-6548-0629; HKE-9636-2023; AFO-6356-2022Background: There is still no approved mechanism of manic switch in bipolar disorder, yet many selective serotonin reuptake inhibitors were accused for this important adverse event. Therefore, we aimed to investigate to estimate SSRI' s risk for reporting mania and elevated mood using FEARS database and investigate receptor mechanisms involved.Methods: Mania and relevant side effects approved by FDA were screened in this dataset from the first quarter of 2004 to the third quarter of 2020. Disproportionality analysis were performed to estimate reporting odds ratio (ROR) and linear regressions were conducted to investigate relationship between ROR and Ki values. Receptor occupancy ratios were calculated from in vitro receptor binding profiles. The pharmacodynamical profile was extracted from the International Union of Basic and Clinical Pharmacology and the British Pharmacology Society dataset. Child and adolescent population was also investigated separately.Results: The analysis showed that the odds of a spontaneous report of mania in the FAERS database involving an SSRI were higher than the odds that such a report involved other types of drugs (ROR: 5.324 [CI: 3.773; 7.514]). The largest effect size in this estimation was found in fluvoxamine (ROR: 13.957 [CI: 10.391; 18.747]). Significant effects were found in regression analysis for Ki values of H1 and M1 receptors on ROR. Receptor occupation was not found to have an effect on ROR.Conclusion: Lower degress of Ki values on M1 and H1 may be plausible pharmacological mechanism. Further pharmacological data and clinical assessments may be important to validate this safety signal.Publication Circulating c1q complement/tnf-related protein (ctrp)-13 levels in obese children and its relationship with metabolic disorders(Karger, 2021-09-01) Erbas, Ibrahim Mert; Paketci, Ahu; Sisman, Ali Riza; Demir, Korcan; Bober, Ece; Abaci, Ayhan; Turan, Serkan; TURAN, SERKAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Psikiyatri Anabilim Dalı.; 0000-0002-8334-2422; 0000-0001-8828-0892; 0000-0002-1812-0321; HKE-9636-2023Publication Impact of the pandemic on the mental health of children and clinical practice in Turkey: A narrative review with recommendations(Exeley, 2021-01-01) Turan, Serkan; Eray, Şafak; TURAN, SERKAN; ERAY ÇAMLI, ŞAFAK; Uludağ Üniversitesi/Tıp Fakültesi/Çocuk ve Ergen Psikiyatrisi; 0000-0002-6548-0629; 0000-0002-4847-7751; HKE-9636-2023; AAG-8101-2021; AFO-6356-2022