Person: BİLGİN, AYŞE KEVSER
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BİLGİN
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AYŞE KEVSER
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Publication Determination of exposure to major iodide ion uptake inhibitors through drinking waters(Elsevier, 2021-12-06) Cengiz, Mehmet Fatih; Sen, Fatih; Bilgin, Ayşe Kevser; Boyacı Gündüz, Cennet Pelin; BİLGİN, AYŞE KEVSER; Keles Meslek Yüksekokulu; Gıda Teknolojisi Bölümü; 0000-0003-1508-5345; AAG-7223-2021Goiter, abnormal enlargement of the thyroid gland, is a significant worldwide public health problem. Iodine deficiency is known as the most common cause. Iodine is actively transported as iodide ion (I-) using Sodium Iodide Symporter (NIS) and sufficient blocking of I- transportation prevents the synthesis of thyroid hormones. The transportation can be blocked by some polyatomic anions known as I- uptake inhibitors. Perchlorate (ClO4-), thiocyanate (SCN-) and nitrate (NO3-) are reported as the major I- uptake inhibitors and exposure could be through various routes. Drinking water is an important exposure route. Since water is essential to sustain life, drinking water safety is very important for the protection of public health. However, as a result of natural and human-based processes, water can be contaminated and contamination of drinking water is a global food safety problem due to causing significant health and environmental problemsIn that context, this study aims to determine exposure levels to I- uptake inhibitors that arise from drinking waters at five different districts in Antalya, Turkey. Collected water samples contained NO3- and ClO4- in the range of 0.86-47.42 mg/L andPublication Elemental compositions and stable isotope signatures for determining the geographical origin of salep orchids collected from different regions of Turkey(Elsevier, 2023-09-15) Bilgin, Ayşe Kevser; Cengiz, Mehmet Fatih; Karakaş-Budak, Barçın; Gümüş, Cevdet; Kılıç, Serpil Aliriz; Perinçek, Fatih; Basançelebi, Onur; Sezik, Ekrem; Certel, Muharrem; BİLGİN, AYŞE KEVSER; Keles Meslek Yüksekokulu; Gıda Teknolojisi Bölümü; 0000-0003-1508-5345; AAG-7223-2021Salep is a highly valued natural food and medicinal commodity with strict regulations on its use and export. It is produced from tubers of orchids and consumed for its delectable and functional qualities in different parts of the world. This study aimed to identify and compare the elemental composition and isotope ratios of salep based on discrimination of geographical origins. The samples were collected from five different regions (North, Southwest, South, Southeast and East Anatolia) of Turkey. The 21 microelements (Li, Be, Ti, V, Cr, Mn, Fe, Ni, Co, Cu, Zn, Ga, Se, Rb, Sr, Mo, Sb, Cs, Ba, Tl and Bi) were determined by inductively coupled plasma mass spectrometry (ICP-MS), while the isotope ratios (313C, 315N, 318O and 32H) were determined using isotope ratio mass spectrometry (IRMS). According to the ICP-MS results, Fe, Zn and Mn comprised around 77% of the elemental composition. North Anatolia samples had higher concentrations of Cr and Ni, while samples from Southeast and East Anatolia regions were enriched in Cs. Isotopic ratios varied significantly between samples and minimum and maximum ratios were determined as -29.76 and -26.63%o, 0 and 6.66%o, 28.09 and 37.31%o, -144.86 and -84.20%o for the 313C, 315N, 318O and 32H, respectively. Collected isotopic data was also evaluated by multivariate statistical analyses to discriminate according to their geographical origins of salep tubers. According to the findings, the samples had a characteristic isotopic fingerprint and the isotope ratios can be important predictors for the discrimination of geographical origins. Results indicate the significant compositional variation between salep of different origins, which may be attributable to differences in environmental conditions such as climate and soil composition and intrinsic factors such as fungal associations of orchids.