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GÜNSEREN, KADİR ÖMÜR

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GÜNSEREN

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KADİR ÖMÜR

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  • Publication
    The effects of laparoscopic urologic surgery on cardiac functions: A pulse wave velocity study
    (Aves, 2020-07-01) Çiçek, Mehmet Çağatay; Kaynak, Yurdaer; Gunseren, Kadir Ömur; Kaygısız, Onur; Vuruşkan, Hakan; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; KAYGISIZ, ONUR; VURUŞKAN, HAKAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0002-0471-5404; 0000-0001-8673-3093; 0000-0002-9790-7295; ABC-9924-2020; L-9439-2019; HGM-5995-2022 ; EFH-9523-2022
    Objective: The aim of this study is to evaluate the effects of laparoscopic urologic surgery on cardiac functions by the parameter pulse wave velocity (PWV), a noninvasive method.Material and methods: Between July 2012 and February 2013, a total of 47 patients were included in this prospective controlled study. Patients who have been scheduled for laparoscopic surgery (LS) (n=30) and open surgery (n=17) were enrolled in the study. Preoperative, perioperative, and postoperative cardiovascular parameters were measured by a PWV instrument, and the results were compared between laparoscopic (L) group and open (C) group.Results: In the L group, compared to preoperative values, perioperative systolic arterial pressure, diastolic arterial pressure, and mean arterial pressure increased considerably, by 2.6%, 7.9%, and 4.7%, respectively. This was in contrary to reductions in these parameters by 9.5%, 5.7%, and 10%, respectively, in the C group. For the I. group, cardiac output (CO) and cardiac index (CI) were increased in the perioperative period and decreased in the postoperative period. For the C group, there were no changes in measurements of perioperative and postoperative CO and CI. However, these changes in CO and CI were not significantly different between the L and C groups. Postoperative large artery elasticity index decreased in both groups. However, these changes did not represent significant difference between groups.Conclusion: Compared to open surgery, LS may cause increases in perioperative blood pressures. In addition, increased blood pressures may last even on the first postoperative day. These effects may be more important for patients with high cardiovascular risk.
  • Publication
    Investigation of the tissue allele distribution of the deceased kidney donors between 2007 and 2017.
    (Lippincott Williams & Wilkins, 2019-11-01) Oflaz, Rafet; Elgin, Ersin; Yıldız, Abdülmecid; Oruç, Ayşegül; Akgür, Suat; Ünsal, Oktay; Karaca, Mert; Ersoy, Sahriye; Selimoğlu, Kerem; Arslan, İlknur; Karan, Elif; Çiçek, Mehmet Çağatay; Günseren, Kadir Ömür; Güllülü, Sümmeyye; Vuruşkan, Hakan; Oflaz, Rafet; Elgin, Ersin; Yıldız, Abdülmecid; ORUÇ, AYŞEGÜL; AKGÜR, SUAT; Ünsal, Oktay; KARACA, MERT; Ersoy, Sahriye; Selimoğlu, Kerem; Arslan, İlknur; Karan, Elif; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; GÜLLÜLÜ, NAZMİYE SÜMEYYE; VURUŞKAN, HAKAN; Tıp Fakültesi; Organ Nakli Merkezi; 0000-0002-9509-5799; 0000-0002-0342-9692; 0000-0003-3635-7282; 0000-0002-3454-8483; 0000-0002-0471-5404; 0000-0001-6711-676X; AAG-7406-2021; AAH-4002-2021; DJU-5362-2022; DXA-2790-2022; EIF-8983-2022; JIX-1144-2023; JJY-8484-2023; AAG-7406-2021; EVS-9805-2022; CDS-3299-2022; CCH-8947-2022; FDB-4488-2022; HGM-5995-2022; EFH-9523-2022; CST-9838-2022; ITO-9188-2023
  • Publication
    Monocyte-to-high-density lipoprotein cholesterol ratio is independently associated with all-cause mortality in deceased donor kidney transplant recipients
    (Başkent Üniversitesi, 2021-10-01) Çiçek, Mehmet Çagatay; Günseren, Kadir Omur; Aydın, Yavuz Mert; Yıldız, Abdulmecit; Elgin, Ersin; Ersoy, Alparslan; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; AYDIN, YAVUZ MERT; YILDIZ, ABDULMECİT; Elgin, Ersin; ERSOY, ALPARSLAN; Tıp Fakültesi; Transplantasyon Bölümü; 0000-0002-0471-5404; 0000-0001-8673-3093; 0000-0002-6287-6767; 0000-0002-9509-5799; ABC-9924-2020; AFP-3055-2022; HGM-5995-2022; HIG-9032-2022; DXA-2790-2022; CPX-5894-2022
    Objectives: The primary objective of this study was to evaluate the impact of monocyte-to-high-density lipoprotein cholesterol ratio on all-cause mortality in deceased donor kidney transplant recipients. Materials and Methods: This was a retrospective observational study in which all deceased donor kidney transplant recipients were included. Relevant data for analyses included clinical and demographic features, laboratory values, number of HLA matches, occurrence of delayed graft function, cold ischemia time, and survival status. Kaplan-Meier survival analysis and Cox proportional hazards analysis were performed to determine the effects of monocyte-tohigh-density lipoprotein cholesterol ratio on all-cause mortality. Results: Our study included 325 deceased donor kidney transplant recipients (43.1% females, mean age of 44.5 +/- 11.2 years). Median value of monocyte-tohigh-density lipoprotein cholesterol ratio was 14.0 (interquartile range, 9.94-21.03). The total median observation time was 227 weeks (range, 115-345 weeks). Twenty deaths (12.3%) occurred during the follow-up period in recipients with monocyte-to-highdensity lipoprotein cholesterol ratio below median value, whereas 47 deaths (29%) occurred in recipients with ratio above the median (P < .001). Log-rank test showed significantly higher mortality in the group with monocyte-to high density lipoprotein cholesterol ratio higher than median (P = .001). In the multivariate Cox model, delayed graft function, duration of dialysis, cold ischemia time, and monocyte-to-high-density lipoprotein cholesterol ratio group appeared as independent predictors of all-cause mortality. Conclusions: Monocyte-to-high-density lipoprotein cholesterol ratio before kidney transplant seems to affect survival independently in deceased donor kidney transplant recipients.
  • Publication
    Comparison of laparoscopic pyelolithotomy and retrograde intrarenal surgery in the management of large renal pelvic stones
    (Wiley, 2021-03-02) Çiçek, Mehmet Çağatay; Asi, Tariq; Günseren, Kadir Ömür; Kılıçarslan, Hakan; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; KILIÇARSLAN, HAKAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0002-0471-5404; 0000-0001-8673-3093; ABC-9924-2020; HGM-5995-2022; FGY-3115-2022
    Background To compare the clinical outcomes of laparoscopic pyelolithotomy (LP) and retrograde intrarenal surgery (RIRS) in the management of large renal pelvic stones.Patients and methods This study included patients who presented with a single renal pelvic stone sized >= 20 mm and who were treated primarily by LP or RIRS. The patients were grouped based on the surgical procedure they underwent. We retrospectively examined and compared the age, the longest axis, and the surface area of the stone, operation time, hospitalization time, complications, and stone-free rates of the two groups.Results Of the 156 patients included in the study, 44 had LP, and 112 had RIRS. Patients who received LP (13 males, 31 females) had a median age of 54 (18-79) years, while those who underwent RIRS (46 males, 66 females) had a median age of 54.5 (18-79). Patients who received LP were found to have larger median stone size (30 mm vs 24 mm, P = .003), longer operation time (100 minutes vs 70 minutes, P = .007), lower complication rate (2% vs 8.9%, P = .063), longer median hospital stay (3 days vs 1 day, P < .001) and better stone-free rate at the third month (90.9% vs 67.9%, P < .001).Conclusion LP is a safe and efficient procedure that could be used as an alternative to RIRS in managing large renal pelvic stones.
  • Publication
    A cut-off value for the operation time and other risk factors in terms of the infection risk for flexible ureterorenoscopy
    (Wiley, 2020-12-01) Demir, Aslan; Celen, Sinan; Gunseren, Kadir Omur; GÜNSEREN, KADİR ÖMÜR; Cicek, Mehmet Cagatay; ÇİÇEK, MEHMET ÇAĞATAY; Kilicarslan, Hakan; KILIÇARSLAN, HAKAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0001-8673-3093; 0000-0002-0471-5404; AAO-8934-2021; ABC-9924-2020
    Objectives To investigate the operation time (OT) and ureteral access sheath (UAS) usage with the infection rates and to determine a cut-off value for OT.Methods We retrospectively analysed the data of the patients who underwent flexible ureterorenoscopy (FURS) for renal stones larger than 20 mm between 2010 and 2019. The investigated parameters were OT, UAS using, and infection status. The data were analysed by forming two groups according to whether the OT was less than 60 minutes and more, whether the UAS was used and whether an infection occurred. In addition, independent risk factors that may affect postoperative urinary infection development were also investigated by logistic regression analysis. And, a Receiver Operating Characteristic (ROC) curve analysis was applied to determine a cut-off value in OT terms, where infection rates increase more.Results A total of 575 patients were enrolled in the study. The rates of the usage of UAS and infection were greater statistically in the group for longer than 60 minutes. OT was longer statistically in the infection group than in the group without infection (94.1 +/- 14.2 and 68.01 +/- 23.1, for groups 1 and 2, respectively, P < .05, Table 2). OT was statistically longer in the UAS group than the unused one (79.3 +/- 24.4 and 66.7 +/- 22.4, for groups 1 and 2, respectively, P < .05, Table 3). ROC analyses revealed a cut-off point of 87.5 min for OT in terms of infection rate.Conclusion While the infection risk increases when OT exceeds 60 minutes, FURS can be safely performed up to 87.5 minutes with 89% sensitivity and 69% specificity infection risk.
  • Publication
    Evaluation of one year, five years and ten years life time of patients with kidney transplant: Single-center experience
    (Lippincott Williams & Wilkins, 2020-09-01) Elgin, Ersin; Aydın, Mehmet Fethullah; Ünsal, Oktay; Yıldız, Abdulmecid; Oruç, Ayşegül; Günseren, Kadir Ömur; Çiçek, Mehmet Çağatay; Budak, Ferah; Oral, H. Barbaros; Ersoy, Alparlan; Elgin, Ersin; Aydın, Mehmet Fethullah; Unsal, Oktay; Yıldız, Abdulmecid; ORUÇ, AYŞEGÜL; GÜNSEREN, KADİR ÖMÜR; ÇİÇEK, MEHMET ÇAĞATAY; BUDAK, FERAH; ORAL, HALUK BARBAROS; Ersoy, Alparlan; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0002-9509-5799; 0000-0002-5665-7402; 0000-0002-0342-9692; 0000-0001-7625-9148; 0000-0003-0463-6818; F-4657-2014; K-7285-2012; AAH-4002-2021; AAJ-8220-2020; IZP-9398-2023; DXA-2790-2022; JKA-8956-2023; JJY-8484-2023; EIF-8983-2022; JJO-6552-2023; CNT-9025-2022
  • Publication
    Single center experience with laparoscopic adrenalectomy on a large clinical series: Lessons learned from 273 cases: A retrospective cohort study
    (Kuwait Medical Association, 2022-12) Çelen, Sinan; Günseren, Kadir Ömur; Vuruşkan, Hakan; Acımış, Nurhan Meydan; Kordan, Yakup; Yavaşcaoğlu, İsmet; GÜNSEREN, KADİR ÖMÜR; VURUŞKAN, HAKAN; YAVAŞCAOĞLU, İSMET; Tıp Fakültesi; Üroloji Bölümü; ITO-9188-2023; EFH-9523-2022; EIN-0828-2022
    Objectives: We aim to evaluate the risk of laparoscopic adrenalectomy (LA) for large adrenal tumors and the risk of learning curve.Design: Single centre, retrospective studySetting: Uludag University, Bursa, TurkeySubjects: A study in a large patient population (N=273) who underwent LA between 2006 and 2017.Interventions: The patients were divided into two study groups according to tumour size as estimated by pathologic specimen maximum diameter, Group A (less than 5cm) and group B (larger than 5cm). In addition, to evaluate learning curve of LA, the patients were divided into two groups according to time interval: the first period was 2006 to 2011, and the second period 2012-2017.Main outcome measures: To evaluate the risk of learning curve and tumour sizeResults: There was no statistical difference between the two groups for per-operative and postoperative complications according to tumour size <5 or >= 5 cm, and there was statistical difference between the two groups for operation time, length of hospital stay; but no statistical difference for postoperative complications according to time interval.Conclusion: LA in large adrenal masses (5 cm or larger) is not associated with longer operative time, increased blood loss and longer hospital stay, without affecting perioperative morbidity, Hence, the size of an adrenal mass should not be the only factor in determining whether LA or not. Besides, learning curve may affect outcomes of LA.
  • Publication
    Laparoscopic ureterolithotomy; an equally effective and a sensible alternative to flexible ureterorenoscopy in the management of large ureteral stones in terms of effectivity and cost
    (Iniestares, S.a., 2021-07-01) Demir, Aslan; Günseren, Kadir Ömür; GÜNSEREN, KADİR ÖMÜR; Çicek, Mehmet Çağatay; ÇİÇEK, MEHMET ÇAĞATAY; Yavasçaoğlu, İsmet; YAVAŞCAOĞLU, İSMET; Kılıçarslan, Hakan; KILIÇARSLAN, HAKAN; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0001-8673-3093; 0000-0002-0471-5404; 0000-0001-8673-3093; ABC-9924-2020; HGM-5995-2022; JIT-9412-2023; EIN-0828-2022
    OBJECTIVES: We aimed to understand whether laparoscopic ureterolithotomy (LU) is a good alternative to flexible ureterorenoscopic lithotripsy (FURS) by comparing these techniques concerning cost-effectiveness.METHODS: We analysed 79 patients with upper ureteral stones larger than 1.5 cm underwent FURS or LU concerning cost-effectiveness analysis. The data including age, body mass index (BMI), stone size, operation time, hospitalisation time, complications and stone-free rates of 15th day and 3rd months. We audited the costs of FURS and LU and compared them concerning cost-effectiveness.RESULTS: There was not any statistically significant difference between the two groups with regard to age, BMI, stone size, stone-free rates at the 3rd month, and complication rates, (p>0.05).The operation times were statistically lower in the FURS than in the LU (61.5 +/- 24.3 min and 140.9 +/- 49.1 min, respectively, p<0.05). The stone-free rate at the 15th day was lower in the FURS group than in the LU group (31 (81.6%) and 41 (100%), respectively, p<0.05) (Table I).However, this statistical difference disappears at 3 months (p>0.05). The mean costs of FURS and LU were $194.2 +/- 12.4 and $179.2 +/- 58.5, respectively (p<0.001).CONCLUSION: FURS is equally effective to LU in terms of stone-free rates. The cost of FURS is higher statistically than LU. FURS is shown as the first choice for the upper ureteral stones larger than 10 mm in size, if the laparoscopic experience is in high-level situations in that clinic, LU may be a suitable alternative to FURS, especially for challenging cases.
  • Publication
    Evaluation of 1 year old graft status of right and left kidneys from the same donor used between 2007 and 2017: Single center experience.
    (Lippincott Williams & Wilkins, 2019-11-01) Elgin, Ersin; Yıldız, Abdülmecid; Oruç, Ayşegül; Akgür, Suat; Ünsal, Oktay; Keskin, Sahriye; Selimoğlu, Kerem; Oflaz, Rafet; Karan, Elif; Arslan, İlknur; Çiçek, Mehmet Çağatay; Günseren, Kadir Ömür; Vuruşkan, Hakan; Ersoy, Alparslan; Elgin, Ersin; Yıldız, Abdülmecid; ORUÇ, AYŞEGÜL; AKGÜR, SUAT; Ünsal, Oktay; Keskin, Sahriye; Selimoğlu, Kerem; Oflaz, Rafet; Karan, Elif; Arslan, İlknur; ÇİÇEK, MEHMET ÇAĞATAY; GÜNSEREN, KADİR ÖMÜR; VURUŞKAN, HAKAN; ERSOY, ALPARSLAN; Tıp Fakültesi; Organ Nakli Merkezi; 0000-0002-9509-5799; 0000-0002-0342-9692; 0000-0003-3635-7282; 0000-0002-3454-8483; 0000-0002-0471-5404; AAH-4002-2021; AAH-5054-2021; DXA-2790-2022; EIF-8983-2022; EJA-1761-2022; JJY-8484-2023; CZH-6714-2022; CDS-3299-2022; DJU-5362-2022; FDB-4488-2022; CCH-8947-2022; HGM-5995-2022; JKA-8956-2023; EFH-9523-2022
  • Publication
    Comparison of local anesthetic efficacy of lidocaine gel and lidocaine gel-intramuscular diclofenac combination in patients undergoing flexible cystoscopy
    (Galenos Yayıncılık, 2018-12-01) Özkan, Arif; Çilesiz, Nusret Can; Kalkanlı, Arif; Günseren, Kadir Ömur; Onuk, Özkan; Hazar, Aydın İsmet; Balcı, Mustafa Bahadir Can; GÜNSEREN, KADİR ÖMÜR; Tıp Fakültesi; Üroloji Ana Bilim Dalı; 0000-0001-8673-3093 ; ABC-9924-2020
    Objective: In this study, we aimed to investigate the effects of 2% lidocaine gel only and 2% lidocaine gel-diclofenac combination on pain in male patients undergoing flexible cystoscopy.Methods: The records of male patients who underwent flexible cystoscopy for lower urinary system symptoms and bladder tumor contol cystoscopy between April 2016, and April 2017, were reviewed. Patients with active urinary infection, urethral stricture, additional procedures during cystoscopy like biopsy, catheter withdrawal, or insertion, and sensory neurological defects were excluded from the study. Patients were divided into two groups according to the analgesic used. Overall, 116 patients in Group I were treated with 2% lidocaine gel, and patients in Group II were treated with 2% lidocaine gel and intramuscular diclofenac. In the gel group, 10 cc of 2% lidocaine gel was instilled into the urethra 15 min before the procedure and immediately before the procedure. In the other group, 75 mg diclofenac was intramuscularly administered 30 min before the 2% lidocaine gel instillation. All operations were performed by the same urologist. VAS scores were filled after the procedure, and the groups were compared.Results: The mean age of the patients was 61 +/- 13.1 years in Group I and 59 +/- 13.2 years in Group II (p=0.060). The mean duration of the procedure was 341 +/- 427 in Group I and 342 +/- 51.1 in Group II (p=0.586). There was a statistically significant difference between the groups in pain scores (group I: 6.1 +/- 2.5; group II: 4.3 +/- 1.7; p<0.001).Conclusion: Intravenous administration of diclofenac, which was performed 30 min before the use of 2% lidocaine gel in males undergoing flexible cystoscopy, provides more effective analgesia than urethral gel alone.