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SAĞLAM, DİLEK

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SAĞLAM

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DİLEK

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    Publication
    Frequency of atopy and allergic disorders among adults with type 1 diabetes mellitus in the southern marmara region of turkey
    (Springer, 2008-03-01) Duran, C.; Ediger, D.; Ersoy, C.; Coşkun, N. F.; Selimoğlu, H.; Ercan, I.; Kıyıcı, S.; Güçlü, M.; Sağlam, D. A.; Ertürk, E.; Tuncel, E.; İmamoğlu, S.; EDİGER, DANE; ERSOY, CANAN; Coşkun, N. Funda; Selimoğlu, Hadi; ERCAN, İLKER; Kıyıcı, Sinem; Güçlü, Metin; SAĞLAM, DİLEK; ERTÜRK, ERDİNÇ; Tuncel, Ercan; İMAMOĞLU, SÜLEYMAN; Uludağ Üniversitesi/Alerji Bilim Dalı/Göğüs Hastalıkları Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji ve Metabolizma Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Alerji Anabilim Dalı/Göğüs Hastalıkları Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.; 0000-0001-9560-180X; 0000-0002-2954-4293; 0000-0003-3604-8826; 0000-0002-2382-290X; 0000-0001-5082-9894; 0000-0003-3604-8826; AAJ-6536-2021; ABF-2367-2020; AAH-8861-2021; ABI-4847-2020; AAE-9142-2019; AAD-1271-2019; FWY-5938-2022; FGL-7924-2022; DNS-0810-2022; EBN-7188-2022; DEA-5443-2022
    Aim: Autoimmune disorders are considered to be associated with a Th1 immune response whereas allergic diseases with a Th2 response. Studies mainly per-Formed on children revealed conflicting results regarding the association of atopy/allergic disease and autoimmune disorders. Therefore, we aimed to investigate the prevalence of allergic diseases in adult Type 1 diabetic patients. Methods: Eighty-nine Type 1 diabetic patients and 64 controls were enrolled into the study. Skin-prick test and European Community Respiratory Health Survey questionnaire were performed on all cases. Patients who gave at least one positive answer to questions about asthma in the questionnaire underwent pulmonary function test and methacholine challenge test. Results: Patients' mean age were similar in diabetic patients and controls (28.2 +/- 8.9 and 28.1 +/- 5.2 yr; respectively). In skin-prick test, the rate Of Positive response to at least one allergen was not significantly different in diabetes (29.2%) and in the control group (31.3%). In European Community Respiratory Health Survey questionnaire, diabetic patients waked up by an attack of cough more than controls did. The rate of physician-diagnosed asthma was similar in both groups. There was no difference between the 2 groups based on the answers of other questions about asthma and other allergic diseases such as allergic rhinitis, eczema, and drug allergy. Conclusion: We found that atopy frequencies were similar in an adult population of Type 1 diabetic patients and controls. Although asthmatic symptom prevalence is increased in diabetic patients, the incidence of current asthma was similar in both groups.