Person: BAKAR, HACI MUSTAFA
Loading...
Email Address
Birth Date
Research Projects
Organizational Units
Job Title
Last Name
BAKAR
First Name
HACI MUSTAFA
Name
26 results
Search Results
Now showing 1 - 10 of 26
Publication Evaluation of intracranial atherosclerotic disease risk factors in patients with acute ischemic stroke(Asean Neurological Assoc, 2023-12-01) DİNÇ, YASEMİN; MESUT, GİZEM; Özpar, Rıfat; Hojjati, Farid; HOJJATI, FARID; ÖZPAR, RİFAT; Bakar, Mustafa; HAKYEMEZ, BAHATTİN; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0001-6649-9287; 0009-0006-2052-6335; IUQ-6999-2023Background & Objective: Intracranial atherosclerotic disease (ICAD) is a prevalent cause of ischemic stroke and is related to recurrent strokes. In this study, we aim to identify the ICAD rate and establish the risk factors in patients with acute ischemic stroke (AIS) in our population in Turkey. Methods: Eight hundred sixty-two patients diagnosed with AIS in our tertiary centre between 01-01.2019 and 01.01.2021 were retrospectively included in this study. Results: We detected ICAD in 172 ( 20%) patients. While the independent risk factors of anterior ICAD were hypertension and diabetes mellitus, the risk factors of posterior ICAD were advanced age, diabetes mellitus, hyperlipidaemia and vertebral artery hypoplasia. There were more frequent posterior ICAD. Conclusion: There was difference in the risk factors for anterior ICAD and posterior ICAD in this Turkish study.Publication Evaluation of clinical, radiological, and demographic characteristics of juxtacortical hemorrhages in cerebral venous thrombosis(Türk Nöroloji Derneği, 2021-12-01) Dinç, Yasemin; Özpar, Rıfat; Bakar, Mustafa; Hakyemez, Bahattin; DİNÇ, YASEMİN; ÖZPAR, RİFAT; BAKAR, HACI MUSTAFA; HAKYEMEZ, BAHATTİN; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0001-6649-9287; 0000-0002-3425-0740; IUQ-6999-2023; AAH-5062-2021; EKN-8251-2022; AAI-2318-2021Objective: Cerebral venous thrombosis (CVT) is a rare form of cerebrovascular disease. Intracranial hemorrhage may occur in 40% of the patients with CVT. The morphology of the intracranial hemorrhages ranges from small juxtacortical hemorrhages (JH) to large parenchymal hematomas. Although it has been suggested that JH is a characteristic of CVT, studies examining the relationship between JH and CVT are limited. In this study, it was aimed to determine the clinical, radiological, and demographic characteristics of JH in patients with CVT.Materials and Methods: In this study, a total of 157 patients who were followed up with the diagnosis of CVT between 2015 and 2021 were included retrospectively. Patients were categorized as, those with and without JH. Variables associated with JH were determined by comparing the demographic, clinical, and radiological characteristics, CVT etiologies and clinical outcomes of the patients.Results: When the clinical, demographic, and radiological characteristics of the patients with and without JH were compared; female gender (p=0.037), clinical initial symptom (0.003), early superior sagittal sinus (SSS) thrombosis (p<0.001), venous collateral scale (VCS) (p<0.001), being in the postpartum period (p=0.006), development of intracranial herniation (p<0.001), and poor clinical outcome (p<0.001) were significantly related with JH. When the significant variables were evaluated with the binary logistic regression, the most significant and independent variables were found to be SSS thrombosis (p=0.043), cortical vein thrombosis (CoVT) (p=0.010), and seizures after CVT (p=0.004). By contrast, no relationships were found between the groups in terms of VCS in binary logistic regression.Conclusion: Diagnosis of CVT is possible with high clinical suspicion and correct interpretation of radiological imaging. JH could be detected with non-contrast cranial computed tomography, which is the first imaging modality, and may cause the clinician to suspect from SSS thrombosis and CoVT. More precise results could be obtained with the prospective multicenter studies.Publication Association of brain volume and cognition in the chronic and episodic migraine patients(Sage Publications, 2013-06-01) Zarifoğlu, Mehmet; Şener, D. K.; Karlı, Nejdet; Hakyemez, Bahattin; Taşkapılıoğlu, Özlem; Özbek, Sevda Erer; Bakar, Mustafa; ZARİFOĞLU, MEHMET; Şener, D. K.; KARLI, HAMDİ NECDET; HAKYEMEZ, BAHATTİN; Taşkapılıoğlu, Özlem; ERER ÖZBEK, ÇİĞDEM SEVDA; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Bölümü; 0000-0003-4436-3797; AAI-2318-2021; AAK-6623-2020; EHN-5825-2022; IOZ-7564-2023; CXD-7623-2022; DLN-1836-2022; EKN-8251-2022Publication Cerebral venous sinus thrombosis in women: Subgroup analysis of the VENOST study(Hindawi, 2020-05-15) Uludüz, Derya; Sahin, Sevki; Duman, Taşkın; Öztürk, Şerefnur; Yayla, Vildan; Afşar, Nazire; Uzuner, Nevzat; Midi, Ipek; Çınar, Nilgün; Sungur, Mehmet Ali; Domaç, Füsun Mayda; İnce, Birsen; Göksan, Baki; Mısırlı, Cemile Handan; Bakar, Mustafa; Kozak, Hasan Hüseyin; Çolakoğlu, Sena; Karahan, Ali Yavuz; Göksu, Eylem Özaydın; Özdağ, Fatih; Şenol, Mehmet Güney; Yürekli, Vedat Ali; Aluçlu, Ufuk; Demir, Serkan; Küçükoğlu, Hayriye; Oruç, Serdar; Yeşilot, Nilüfer; Küsbeci, Özge Yımaz; Nazliel, Bijen; Tokuç, Firdevs Ezgi Uçan; Bektaş, Hesna; Taşcılar, Fatma Nida; Aytaç, Emrah; Gökçe, Mustafa; Çağlayan, Hale Zeynep Batur; Tüfekci, Ahmet; Uzuner, Gülnur; Örken, Dilek Necioğlu; Yalın, Osman Özgür; Utku, Uygar; Yılmaz, Arda; Genç, Hamit; Çabalar, Murat; Milanlıoğlu, Ayşel; Ekmekci, Hakan; Zeydan, Burcu; Baybas, Sevim; Kablan, Yüksel; Göksel, Başak Karakurum; Açıkgöz, Mustafa; Kurucu, Hatice; Demirci, Seden; Güneş, Taşkın; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; EKN-8251-2022Background. Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group.Methods. Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF.Results. The mean age of the RHRF (-) group (43.2 +/- 13 years) was significantly higher than of the RHRF (+) group (34 +/- 9years). A previous history of deep venous thrombosis (3%), isolated cavernous sinus involvement (1%), cranial neuropathy (13%), comorbid malignancy (7%), and its disability scores after 12 months (9%) were significantly higher in the RHRF (-) group. The RHRF (+) group consisted of 44% cases of puerperium, 33% cases of OC users and 23% of pregnant women. The mean age was found to be higher in OC users (38 +/- 9years). A previous history of deep venous thrombosis was slightly higher in the pregnancy subgroup (4%). Epileptic seizures were more common in the puerperium group (44%).Conclusion. The results of our study indicate that the risk of CSVT increases parallel to age, OC use, and puerperium period. In addition, when considering the frequency of findings and symptoms, epileptic seizures in the puerperium subgroup of the RHRF (+) group and malignancies in the RHRF (-) group may accompany the CSVT. In daily practice, predicting these risks for the CSVT and early recognition of the symptoms will provide significant benefits to patients.Publication The relationship between early neurological deterioration, poor clinical outcome, and venous collateral score in cerebral venous sinus thrombosis(Wolters Kluwer Medknow Publications, 2021-07-01) Dinç, Yasemin; Özpar, Rıfat; Hakyemez, Bahattin; Bakar, Mustafa; DİNÇ, YASEMİN; ÖZPAR, RİFAT; HAKYEMEZ, BAHATTİN; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Radyoloji Ana Bilim Dalı; 0000-0001-6649-9287; 0000-0002-3425-0740; 0000-0003-0342-5939; IWC-9957-2023; AAH-5062-2021; AAI-2318-2021; EKN-8251-2022Background and Purpose: Cerebral venous sinus thrombosis (CVST) is one of the rare causes of cerebrovascular disease and has an extremely heterogeneous prognosis. The aim of this study was to investigate the potential relationship between early neurological deterioration, poor clinical outcome in CVST and the venous collateral score. Materials and Methods: A total of 121 patients diagnosed with CVST between 2010 and 2020 were retrospectively included. The demographic, clinical, and radiological findings related to venous sinus thrombosis and early neurological deterioration were investigated in relation to the clinical outcome. Results: The factors associated with early neurological deterioration were superior sagittal sinus thrombosis (P < 0.001), sinus rectus thrombosis (P = 0.031), parenchymal lesions (P < 0.001), and venous collateral score (P < 0.001). The factors associated with poor clinical outcome were superior sagittal sinus thrombosis (P < 0.001), cortical vein thrombosis (P < 0.001), venous collateral score (P < 0.001), and initial clinical symptoms. Binary logistic regression analyses revealed poor clinical outcome as a significant variable, with a venous collateral scale of 0 or 1 as a risk factor for a poor outcome (significance of the model P < 0.001). Conclusion: Early neurologic deterioration and poor clinical outcome may occur due to poor collateralization in CVST. Identifying the subgroup of CVST patients at risk of clinical deterioration is therefore important. This study highlights the clinical importance of venous collaterals; however, larger prospective multicenter studies are required to confirm the relationship with venous collaterals in patients with CVST.Publication Identifying the risk factors of early neurological deterioration after thrombolysis in patients with acute ischemic stroke(Galenos Yayıncılık, 2022-09-01) Dinç, Yasemin; Özpar, Rıfat; Hakyemez, Bahattin; Bakar, Hacı Mustafa; DİNÇ, YASEMİN; ÖZPAR, RİFAT; HAKYEMEZ, BAHATTİN; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0001-6649-9287; 0000-0003-0342-5939; 0000-0002-3425-0740; 0000-0001-5229-0001; IUQ-6999-2023; AAH-5062-2021; AAI-2318-2021; EKN-8251-2022Objective: The efficacy of intravenous (IV) recombinant tissue plasminogen activator (rt-PA) therapy in the treatment of acute ischemic stroke (AIS) has been demonstrated in many studies and IV rt-PA therapy has been increasingly used all over the world. Early neurological deterioration (END) in AIS is common and potentially associated with a poor clinical outcome. The prevalence of END in AIS ranges from 13% to 37% in studies. The aim of this study is to determine the prevalence and risk factors of END in patients with AIS receiving IV rt-PA therapy. Materials and Methods: One hundred fifty seven patients who were given IV rt-PA treatment by Bursa Uludag University Faculty of Medicine, Department of Neurology between 01.01.2020 and 01.01.2021 were retrospectively included in this study. It was planned to determine the risk group by comparing patients with END with those without. Results: Age (p=0.023), serum glucose level (p=0.045), The National Institutes of Health Stroke score at discharge (p<0.01), Alberta Stroke Program Early CT (ASPECT) score (p<0.01) when clinical, radiological and demographic data associated with END were evaluated and, statistically significant correlation was found with the presence of major vessel occlusion (p=0.012), ischemic stroke due to cardioembolism (p=0.002), clinical outcome (p<0.001) and symptomatic intracerebral hemorrhage (p<0.001). When the significant variables associated with END were evaluated with binary logistic regression, the most significant variables were found to be age (p=0.006) and ASPECT score (p<0.001). Conclusion: The causes of END are multifactorial. The most associated risk factors were found to be advanced age and low ASPECT score. It was understood that the most common cause of END was the inability to perform mechanical thrombectomy for major vessel occlusion. Contrary to popular belief, the most common cause of END in patients with AIS who received IV rt-PA treatment was not considered to be symptomatic intracranial hemorrhage but to inadequate recanalization or late recanalization.Publication Juxtacortical hemorrhage in cerebral venous thrombosis: Cashew nut sign(Türk Nöroloji Derneği, 2021-09-01) Dinç, Yasemin; Güllü, Gizem; Hakyemez, Bahattin; Bakar, Mustafa; DİNÇ, YASEMİN; GÜLLÜ, GİZEM; HAKYEMEZ, BAHATTİN; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0003-0342-5939; 0000-0001-9477-5031; 0000-0002-3425-0740; 0000-0001-5229-0001; IUQ-6999-2023; JFC-5005-2023; AAI-2318-2021; EKN-8251-2022Publication Gastrostomy in hospitalized patients with acute stroke: "Norotek" Turkey point prevalence study subgroup analysis(Galenos Yayıncılık, 2022-09-01) Topçuoğlu, Mehmet Akif; Özdemir, Atilla Özcan; Aykaç, Özlem; Milanoğlu, Aysel; Gökçe, Mustafa; Bavli, Songül; Çabalar, Murat; Yayla, Vildan; Erdoğan, Hacı Ali; Özkul, Ayça; Güneş, Aygül; Değirmenci, Bahar; Aluçlu, Ufuk; Kozak, Hasan Hüseyin; Güngör, Levent; Erdoğan, Mucahid; Acar, Zeynep Özdemir; Cenikli, Utku; Kablan, Yüksel; Yılmaz, Arda; Genç, Hamit; Nazliel, Bijen; Çağlayan, Hale Batur; Gencer, Elif Sarıönder; Ay, Halil; Demirbaş, Hayri; Akdoğan, Özlem; Emre, Ufuk; Yıldız, Özlem Kayim; Bolayır, Aslı; Demir, Turgay; Tanrıverdi, Zeynep; Tekan, Ulgen Yalaz; Akpınar, Çetin Kurşad; Özkan, Esra; Ilık, Faik; Şirin, Hadiye; Güler, Ayşe; Önder, Halil; Bektaş, Hesna; Oçek, Levent; Bakar, Mustafa; Ongün, Nedim; Krespi, Yakup; Işıkay, Canan Togay; Aslanbaba, Eda; Sorgun, Mine; Gürkaş, Erdem; Karadeli, Hasan Hüseyin; Midi, İpek; Ilgezdi, Irem; Bilgiç, Adnan Burak; Akyol, Şener; Epceliden, M. Tuncay; Atmaca, Murat Mert; Kurşun, Oğuzhan; Keskin, Onur; Sırınocak, Pınar Bekdik; Baydemir, Recep; Akçakoyunlu, Merve; Öztürk, Serefnur; Özel, Tuğba; Unal, Ali; Dora, Babur; Yürekli, Vedat Ali; Arlier, Zülfikar; Eren, Alper; Yılmaz, Ayse; Kısabay, Aysun; Acar, Bilgehan; Baştan, Birgül; Acar, Zeynep; Niflioğlu, Buket; Güven, Bülent; Kaya, Dilaver; Afşar, Nazire; Yazici, Duran; Aytaç, Emrah; Yaka, Erdem; Toplutaş, Eren; Degirmenci, Eylem; İnce, Fatma Birsen; Büyükserbetçi, Gülseren; Aydın, İsa; Çetiner, Mustafa; Sen, Mustafa; Turgut, Nilda; Kale, Nilufer; Çoban, Eda; Yeşilot, Nilufer; Ekizoğlu, Esme; Kizek, Özgü; Birgili, Özlem; Yevgi, Recep; Kunt, Refik; Giray, Semih; Akkaş, Sinem Yazıcı; Senadim, Songül; Yoldaş, Tahir; Asıl, Talip; Duman, Taşkın; Atasoy, Tuğrul; Çınar, Bilge Piri; Demir, Tulin; Can, Ufuk; Unsal, Yaprak Özüm; Eskut, Neslihan; Aslan, Yıldız; Baş, Demet Funda; Şener, Ufuk; Yılmaz, Zahide; Bozdoğan, Zehra; Alioğlu, Zekeriya; Arsava, Ethem Murat; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; EKN-8251-2022Objective: Nutritional status assessment, dysphagia evaluation and enteral feeding decision are important determinants of prognosis in acute neurovascular diseases. Materials and Methods: NoroTek is a point prevalence study conducted with the participation of 87 hospitals spread across all health sub regions of Turkey conducted on 10-May-2018 (World Stroke Awareness Day). A total of 972 hospitalized neurovascular patients [female: 53%, age: 69 +/- 14; acute ischemic stroke in 845; intracerebral hematoma (ICH) in 119 and post-resuscitation encephalopathy (PRE) in 8] with complete data were included in this sub-study. Results: Gastrostomy was inserted in 10.7% of the patients with ischemic stroke, 10.1% of the patients with ICH and in 50% of the patients with PRE. Independent predictors of percutaneous endoscopic gastrostomy (PEG) administration were The National Institutes of Health Stroke Scale score at admission [exp (ss): 1.09 95% confidence interval (CI): 1.05-1.14, per point] in ischemic stroke; and mechanical ventilation in ischemic [exp (ss): 6.18 (95% CI: 3.16-12.09)] and hemorrhagic strokes [exp (ss): 26.48 (95% CI: 1.36-515.8)]. PEG was found to be a significant negative indicator of favorable (modified Rankin's scale score 0-2) functional outcome [exp (ss): 0.032 (95% CI: 0.004-0.251)] but not of in-hospital mortality [exp (ss): 1.731 (95% CI: 0.785-3.829)]. Nutritional and swallowing assessments were performed in approximately two-thirds of patients. Of the nutritional assessments 69% and 76% of dysphagia assessments were completed within the first 2 days. Tube feeding was performed in 39% of the patients. In 83.5% of them, tube was inserted in the first 2 days; 28% of the patients with feeding tube had PEG later. Conclusion: The NoroTek study provided the first reliable and large-scale data on key quality metrics of nutrition practice in acute stroke in Turkey. In terms of being economical and accurate it makes sense to use the point prevalence method.Publication Evaluation of the relationship between epileptic seizures and type of parenchymal lesion in patients with cerebral venous thrombosis(Wolters Kluwer Medknow Publications, 2022-01-01) Dinç, Yasemin; DİNÇ, YASEMİN; Demir, Aylin; BİCAN DEMİR, AYLİN; Bora, Ibrahim; Bakar, Mustafa; BAKAR, HACI MUSTAFA; BORA, İBRAHİM HAKKI; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0001-6739-8605Introduction: Epileptic seizures occur in approximately 35%-40% of patients with cerebral venous thrombosis (CVT). The relationship between parenchymal lesions and epileptic seizures in CVT has been investigated, but the most associated types of parenchymal lesions have not been determined. This study, therefore, aimed to identify high-risk groups. Methods: A total of 159 patients were diagnosed as having CVT between 2015 and 2021 at our tertiary center. The risk factors for epileptic seizures after CVT were determined. Results: A total of 159 patients who were diagnosed with having CVT, 109 (68.5%) females and 50 (31.5%) males, were included in this study. The mean ages of the women and men were 41.20 & PLUSMN; 14.15 years and 43.60 & PLUSMN; 16.30 years, respectively. We found that superior sagittal sinus involvement (P = 0.019), sigmoid sinus involvement (P = 0.010), cortical vein involvement (P < 0.001), parenchymal lesion (P < 0.001), and the postpartum period (P = 0.003) increased the risk of epileptic seizures. When the significant variables associated with epileptic seizures in the patients were analyzed using binary logistic regression, the most significant variable was found to be the presence of parenchymal lesions. Conclusion: We found that the most significant variable for epileptic seizures after CVT was parenchymal lesions. Juxtacortical hemorrhages and nonhemorrhagic venous infarcts were the most common causes of epileptic seizures. CVT is a heterogeneous group of diseases caused by multiple aetiologies and may show ethnic and racial differences. For this reason, more precise information can be obtained with multi-center prospective studies in our population.Publication Specificity and sensitivity of the SeLECT score in predicting late seizures in patients undergoing intravenous thrombolytic treatment and the effect of diabetes mellitus and leukoaraiosis(Assoc Arquivos Neuro- Psiquiatria, 2023-03-01) Dinç, Yasemin; Demir, Aylin Bican; Özkaya, Güven; Bakar, Mustafa; DİNÇ, YASEMİN; BİCAN DEMİR, AYLİN; ÖZKAYA, GÜVEN; BAKAR, HACI MUSTAFA; Tıp Fakültesi; Nöroloji Ana Bilim Dalı; 0000-0003-0297-846X; 0000-0003-0342-5939; IUQ-6999-2023; A-4421-2016; IWC-9957-2023; KHB-9765-2024; EKN-8251-2022Background Seizures after stroke can negatively affect the prognosis of ischemic stroke and cause a decrease in quality of life. The efficacy of intravenous (IV) recombinant tissue plasminogen activator (rt-PA) treatment in acute ischemic stroke has been demonstrated in many studies, and IV rt-PA treatment has been increasingly used around the world. The SeLECT score is a useful score for the prediction of late seizures after stroke and includes the severity of stroke (Se), large artery atherosclerosis (L), early seizure (E), cortical involvement (C), and the territory of the middle cerebral artery (T). However, the specificity and sensitivity of the SeLECTscore have not been studied in acute ischemic stroke patients that received IV rt-PA treatment.Objective In the present study, we aimed to validate and develop the SeLECT score in acute ischemic stroke patients receiving IV rt-PA treatment.Methods The present study included 157 patients who received IV thrombolytic treatment in our third-stage hospital. The 1-year seizure rates of the patients were detected. SeLECT scores were calculated.Results In our study, we found that the SeLECT score had low sensitivity but high specificity for predicting the likelihood of late seizure after stroke in patients administered IV rt-PA therapy. In addition to the SeLECTscore, we found that the specificity and sensitivity were higher when we evaluated diabetes mellitus (DM) and leukoaraiosis.Conclusion We found that DM was an independent risk factor for late seizures after stroke in a patient group receiving thrombolytic therapy, and late seizures after stroke were less frequent in patients with leukoaraiosis.
- «
- 1 (current)
- 2
- 3
- »