Person: MELEK, HÜSEYİN
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MELEK
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HÜSEYİN
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Publication Comparison of survival results of patients with t0 and t1-2-3 in pathological t staging in patients with non-small cell lung cancer who underwent surgery after neoadjuvant treatment(Termedia Publishing House, 2020-01-01) Kermenli, Tayfun; Melek, Hüseyin; Bayram, Ahmet Sami; Gebitekin, Cengiz; MELEK, HÜSEYİN; BAYRAM, AHMET SAMİ; GEBİTEKİN, CENGİZ; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; 0000-0003-0684-0900; 0000-0003-1822-8153; AAE-1069-2022; AAI-5039-2021; JCE-0097-2023; ABB-7580-2020Aim: In this study, we aimed to compare the survival results of patients who underwent neoadjuvant treatment with NSCLC between March 1997 and August 2014 and were found to have T0N0 and T1-2-3/N0.Material and methods: A hundred ninety-five patients who had complete neoadjuvant therapy, complete lung resection and lymph node dissection, and pathologically diagnosed as T0 or T1-2-3/N0, M0 were included in the study.Results: Of the 195 patients included in the study, 181 were male, 14 were female and the mean age of the patients was 57.9. The mean age of the groups was as follows: group 1: 58.1, group 2: 57.7, group 3: 59.7 and group 4: 56.8. In our series the most common complication was atelectasis (n = 19). Others were prolonged air leak (n = 16), pneumonia (n = 12), apical pleural space (n = 6), wound infection (n = 3), cardiac problems (n = 3), hematoma (n = 3), bronchopleural fistula (n = 3), empyema (n = 2), chylothorax (n = 1). The 5-year survival rate for patients in the T0N0 group was 76.3%. This rate was 71.8% in group 2, 63.6% in group 3 and 44.1% in group 4.Conclusions: Survival was found to be better in patients who underwent surgery after neoadjuvant therapy and had a complete pathological response. We believe that we can provide better results with the increase in the number of cases detected as TxN0 after the neoadjuvant treatment and prolongation of the follow-up period.Publication Diagnostic value of cervical mediastinoscopy: Report of 506 cases(European Respiratory, 2013-09-01) Erol, Mehmet; Melek, Hüseyin; Bayram, Ahmet; Kermenli, Tayfun; Coşkun, Funda; Akyıldız, Elif; Gebitekin, Cengiz; Erol, Mehmet; MELEK, HÜSEYİN; BAYRAM, AHMET SAMİ; Kermenli, Tayfun; COŞKUN, NECMİYE FUNDA; AKYILDIZ, ELİF ÜLKER; GEBİTEKİN, CENGİZ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Kliniği; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Bölümü; Uludağ Üniversitesi/Tıp Fakültesi/Patholoji Bölümü; 0000-0003-0684-0900; 0000-0002-7371-4026; 0000-0003-3604-8826; AAE-1069-2022; AAD-1271-2019; AAI-5039-2021; JCE-0097-2023; ABB-7580-2020; KHO-7454-2024; A-6612-2019; IAV-7890-2023Publication The importance of lymphatic and vascular invasion in stage 1 non-small cell lung cancer and definition of a totally curable tumors(Elsevier Science Inc, 2019-10-01) Turna, Akif; Sarbay, İsmail; Kara, H.; Kaynak, Kamil; Melek, Hüseyin; MELEK, HÜSEYİN; Gebitekin, Cengiz; GEBİTEKİN, CENGİZ; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; AAI-5039-2021; AAE-1069-2022Publication The survival effect of resection of cranial metastatic lesions in patients with lung cancer(Elsevier Science, 2015-09-01) Deligönül, Adem; Taşkapılıoğlu, Özgür; Melek, Hüseyin; Bekar, Ahmet; Çetinkaya, Gamze; Sarihan, Süreyya; Bayram, Ahmet Sami; Gebitekin, Cengiz; Evrensel, Türkkan; DELİGÖNÜL, ADEM; TAŞKAPILIOĞLU, MEVLÜT ÖZGÜR; MELEK, HÜSEYİN; BEKAR, AHMET; Çetinkaya, Gamze; SARIHAN, SÜREYYA; BAYRAM, AHMET SAMİ; GEBİTEKİN, CENGİZ; EVRENSEL, TÜRKKAN; Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Tıbbi Onkoloji Bilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Beyin ve Sinir Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.; 0000-0001-5472-9065; 0000-0003-4816-5798; 0000-0003-0684-0900; AAI-5039-2021; ABX-9081-2022; AAH-4970-2021; AAE-1069-2022; JDW-2654-2023; AAJ-1027-2021; JCE-0097-2023; ABB-8161-2020; ABB-7580-2020Publication The success of surgery in the first 24 hours in patients with esophageal perforation(Aves Yayıncılık, 2015-02-01) Bayram, Ahmet Sami; Erol, Mehmet Muharrem; Melek, Hüseyin; Çolak, Mehmet Ali; Kermenli, Tayfun; Gebitekin, Cengiz; BAYRAM, AHMET SAMİ; Erol, Mehmet Muharrem; MELEK, HÜSEYİN; Çolak, Mehmet Ali; Kermenli, Tayfun; GEBİTEKİN, CENGİZ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0003-0684-0900; 0000-0002-7371-4026; 0000-0003-1822-8153; ABB-7580-2020; KHE-8874-2024; AAI-5039-2021; JIM-7704-2023; A-6612-2019; AAE-1069-2022Objective: Esophageal perforation (EP) is a critical and potentially life-threatening condition with considerable rates of morbidity and mortality. Despite many advances in thoracic surgery, the management of patients with EP is still controversial.Materials and Methods: We retrospectively reviewed 34 patients treated for EP, 62% male, mean age 53.9 years. Sixty-two percent of the EPs were iatrogenic. Spontaneous and traumatic EP rates were 26% and 6%, respectively. Three patients had EP in the cervical esophagus and 31 in the thoracic esophagus.Results: Mean time to initial treatment was 34.2 hours. Twenty patients comprised the early group <24 h) and 14 patients the late group (>24 h). Management of the EP included primary closure in 30 patients, non-surgical treatment in two, stent in one and resection in one. Mortality occurred in nine of the 34 patients (26%). Mortality was EP-related in four patients. Three of the nine patients that died were in the early group (p<0.05). Mean hospital stay was 13.4 days.Conclusion: EP remains a potentially fatal condition and requires early diagnosis and accurate treatment to prevent the morbidity and mortality.Publication Can thoracic sympathetic nerve damage be reversed?(Georg Thieme Verlag, 2015-12-01) Erol, M. Muharrem; Salcı, Hakan; Melek, Hüseyin; İlhan, Tuncay; Özfiliz, Nesrin; Bayram, Ahmet Sami; Gebitekin, Cengiz; Erol, M. Muharrem; SALCI, HAKAN; MELEK, HÜSEYİN; İLHAN, TUNCAY; ÖZFİLİZ, NESRİN; BAYRAM, AHMET SAMİ; GEBİTEKİN, CENGİZ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Cerrahi Anabilim Dalı.; Uludağ Üniversitesi/Veteriner Fakültesi/Histoloji Anabilim Dalı.; 0000-0003-0684-0900; 0000-0003-1822-8153; AAI-5039-2021; AAE-1069-2022; AAH-2756-2021; JCE-0097-2023; AAH-8859-2021; ABB-7580-2020; T-4623-2019; KHE-8874-2024Background Function of the thoracic sympathetic chain (TSC) reportedly recovers after surgical clips are removed. Hence, this study was designed to study nerve regeneration after unclipping the TSC.Methods The bilateral TSCs of six goats were studied; the goats were separated into three groups (groups I, II, and III) during excision, clipping, and unclipping. During surgery, the TSCs were excised with a scalpel in group I and clipped in groups II and III. In group III, the clips were removed 1 month postoperatively and observed for possible nerve healing for 1 month. All TSCs were examined histologically following en block resection at 1 month postoperatively in groups I and II and at 2 months postoperatively in group III.Results Inflammation in nerve sections was noted following clip removal. Furthermore, there was significant degeneration and cell infiltration in the nerve fibers of the clipped regions. The Schwann cells around the peripheral nerve endings in the unclipped regions facilitated nerve transmission by reconstitution of myelin.Conclusion Clipping the TSC can cause histologic degeneration; however, histologic nerve regeneration occurs after unclipping.Publication Cricothyroidotomy performed by seldinger method in the management postoperative sputum retention and atelectasis after lung resection(Bayçınar Medikal Yayın, 2015-01-01) Melek, Hüseyin; Çetinkaya, Gamze; Erol, Mehmet Muharrem; Kaya, Fatma Nur; Bayram, Ahmet Sami; MELEK, HÜSEYİN; Çetinkaya, Gamze; Erol, Mehmet Muharrem; KAYA, FATMA NUR; BAYRAM, AHMET SAMİ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı; Uludağ Üniversitesi/Tıp Fakültesi/Anestezi ve Reanimasyon Anabilim Dalı; 0000-0003-0684-0900; 0000-0002-4848-1566; JDW-2654-2023; AAI-5039-2021; ABB-7580-2020; KHE-8874-2024; CXE-4995-2022Mini-tracheotomy is a safe and effective method in the prevention and treatment of postoperative sputum retention and atelectasis. It can be applied under general anesthesia or local anesthesia. Minitracheotomy-related complications are usually preventable and are rare. In this article, we present the outcomes of Mini-Trach II (R) Portex Seldinger kit application technique under the guidance of rigid bronchoscopy in patients with atelectasis and sputum retention after lung resection.Publication Application of rigid broncoscopy with heated serum physiologic(Galenos Yayıncılık, 2012-12-01) Erol, Mehmet Muharrem; Melek, Hüseyin; Girgin, Nermin Kelebek; Bayram, Ahmet Sami; Erol, Mehmet Muharrem; MELEK, HÜSEYİN; KELEBEK GİRGİN, NERMİN; BAYRAM, AHMET SAMİ; Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.; 0000-0003-0684-0900; AAI-5039-2021; ABB-7580-2020; AAH-7250-2019; KHE-8874-2024Rigid bronchoscopy (RB) is a procedure commonly performed thoracic surgery is quite routine. The main application areas of bronchoscopy; foreign body aspiration, atelectasis, control of hemoptysis and diagnostic procedures. In bronchoscopy, cold Serum Physiologic (SP) is used for irrigation. In this article, we present a case used warm SP in order to open an atelectasis during broncoscopy that have never been used in the literature.Publication Message from the patients: What if i wasn't COVID 19(Elsevier Science Inc, 2023-11-01) Süleymanov, E.; Melek, H.; Gebitekin, C.; Süleymanov, E.; MELEK, HÜSEYİN; GEBİTEKİN, CENGİZ; Bursa Uludağ Üniversitesi/Tıp Fakültesi.; HGI-2141-2022; HNE-9801-2023; JYM-2153-2024Publication Lung cancer surgery in patients with a history of coronary artery bypass graft: A multicentre study(Elsevier Science, 2021-02-17) Akçam, Tevfik İlker; Samancılar, Özgür; Yazgan, Serkan; Ceylan, Kenan Can; Kocatürk, Celalettin İbrahim; Sezen, Celal Buğra; Tezel, Cağatay Salim; Gürer, Deniz; Bayram, Ahmet Sami; Melek, Hüseyin; Özkan, Berker; Ülker, Melike Güler; Kaba, Erkan; Toker, Alper; BAYRAM, AHMET SAMİ; MELEK, HÜSEYİN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Cerrahisi Anabilim Dalı.; 0000-0003-1822-8153 ; 0000-0003-0684-0900 ; AAI-5039-2021 ; ABB-7580-2020Background Lung cancer surgery may be required for patients with a history of coronary artery bypass graft (CABG). In this study, we evaluated the general characteristics of patients, the difficulties experienced during and after lung cancer surgery and complications and mortality rates.Method Patients who were operated on for primary lung cancer between January 2012 and July 2017 in the participating centres were analysed retrospectively (n=7,530). Patients with a history of CABG (n=220) were examined in detail. This special group was analysed and compared with other patients operated on for lung cancer who did not have CABG (n=7,310) in terms of 30-day mortality and revision for haemorrhage.Results Of the 7,530 patients operated on for primary lung cancer, 2.9% were found to have undergone CABG. Surgical revision was required in the early postoperative period for 6.8% of those who had CABG and 3.5% in those who did not have CABG (p=0.009). Thirty-day (30-day) mortality was 4.5% in those who had CABG and 2.9% in those who did not have CABG (p=0.143). Further analysis of patients who had undergone CABG demonstrated that video-assisted thoracoscopic surgery (VATS) resulted in fewer complications (p=0.015). Patients with a left-sided left internal mammary artery (LIMA) graft had a higher number of postoperative complications (p=0.30).Conclusions Patients who had CABG suffered postoperative haemorrhage requiring a revision twice as often, and a tendency towards higher mortality (non-statistically significant). In patients with a history of CABG, VATS was demonstrated to have fewer complications. Patients with a LIMA graft who had a left-sided resection had more postoperative complications.