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GENÇ, ABDÜSSELAM

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GENÇ

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ABDÜSSELAM

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    Publication
    A novel technique of pulmonary artery banding by means of radiofrequency ablation: An experimental study in rabbits
    (Bayçınar Tıbbi Yayıncılık, 2022-07-01) Uysal, Fahrettin; Akça, Tuğberk; Genç, Abdüsselam; Küpeli, Zehra Avcı; Özfırat, Erencan; Canatan, Uygur; Uysal, Berfin; Sığnak, Işık Şenkaya; UYSAL, FAHRETTİN; AKÇA, TUĞBERK; GENÇ, ABDÜSSELAM; KÜPELİ, ZEHRA AVCI; ÖZFIRAT, ERENCAN; CANATAN, UYGUR; ŞENKAYA SIĞNAK, IŞIK; 0000-0002-2747-974X; AAH-4421-2021; AEX-4557-2022; CQK-7120-2022; FHA-3247-2022; JHY-2022-2023; CJU-7194-2022; GPN-0680-2022
    Background: The aim of this study was to evaluate the efficacy and feasibility of a novel method of narrowing pulmonary arteries with catheter angiography using radiofrequency energy in rabbits. Methods: A total of nine New Zealand white rabbits weighing 3.0 to 4.2 kg each were utilized in this experimental study. After the location of pulmonary artery was confirmed by echocardiography and angiography, radiofrequency energy was applied by starting with 5 W energy for the first time and increasing by 5 W, if there was no rupture to a maximum of 20 W. Multiple applications of radiofrequency energy with different durations were performed at different levels of the pulmonary artery. Eight weeks later, surviving rabbits were sacrificed. The pulmonary arteries were removed for histological investigation. Results: Five rabbits remained alive after the experiment. There was a significant correlation between radiofrequency power and the degree of vessel thickness change in the pulmonary artery. The endothelial integrity of the tunica intima was impaired in all groups and the diameter of vessel was thickened by an average of 3.5 times. Conclusion: The narrowing of the pulmonary artery using radiofrequency energy was successfully performed in a small sample size of experimental animals in this study.
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    Publication
    The role of external loop recorders in arrhythmia-related symptoms in children: A single center experience
    (Springer, 2021-08-13) Akça, Tuğberk; Uysal, Fahrettin; Bostan, Özlem Mehtap; Genç, Abdusselam; Türkmen, Hasan; AKÇA, TUĞBERK; UYSAL, FAHRETTİN; BOSTAN, ÖZLEM MEHTAP; GENÇ, ABDÜSSELAM; TÜRKMEN, HASAN; Bursa Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Kardiyoloji Bölümü; 0000-0001-7707-2174; 0000-0002-2747-974X; AEX-4557-2022; AAH-4421-2021; AAG-8558-2021; CQK-7120-2022; JKC-8556-2023
    In this study, we report our experience with the use of external loop recorders (ELRs), in terms of diagnostic efficiency according to symptoms and symptom-rhythm correlation in pediatric patients. We evaluated ELRs applied to 178 patients between April 2017 and November 2020 at our center. The mean age of 172 patients included in the study was 13.6 +/- 3.8 years, and 69.8% were female. ELR indications were palpitations in 98 (56.9%) cases, chest pain and palpitations in 43 (25%) cases, presyncope/syncope in 28 (16.2%) cases, and pacemaker/ implantable cardioverter-defibrillator (ICD) problems in 3 (0.2%) cases. ELR recording times were 14.2 +/- 9.7 days on average, ranging from 2 to 67 days. While the symptom-rhythm correlation was 29.1% in total, when the indications were evaluated one by one, this correlation was found to be 30.2% in palpitations, 34.7% in chest pain and palpitations, and 10.7% in presyncope/syncope. The total diagnostic efficiency was 68.1%. In the follow-up of ELR cases, a total of 139 (80.8%) patients received clinical follow-up without medication, 15 (8.8%) patients received medical treatment, and 18 (10.4%) patients underwent EPS. The cardiac ELR system is useful in detecting underlying arrhythmias. Demonstrating sinus tachycardia at the time of the symptom may be seen as negative finding, but while experiencing symptoms, it is diagnostically valuable and may help avoid further investigation with costly and invasive diagnostic procedures. For diagnostic efficiency and cost effectiveness, the optimal recording time is 2 weeks, but it should be extended to 4 weeks in cases such as of presyncope/syncope that cannot be explained with a 2-week ELR use.